Journal of Antimicrobial Chemotherapy

Leading articles:

H Labischinski, K Ehlert, and B Berger-Bachi

The targeting of factors necessary for expression of methicillin resistance in staphylococci
J. Antimicrob. Chemother. 1998 41: 581-584; doi:10.1093/jac/41.6.581 [PDF] [Request Permissions]  

Reviews:

I Chopra

Over-expression of target genes as a mechanism of antibiotic resistance in bacteria
J. Antimicrob. Chemother. 1998 41: 584-588; doi:10.1093/jac/41.6.584 [PDF] [Request Permissions]  

GN Rolinson

Forty years of beta-lactam research
J. Antimicrob. Chemother. 1998 41: 589-603; doi:10.1093/jac/41.6.589 [Abstract] [PDF] [Request Permissions]  

Original articles:

MA Cohen, MD Huband, SL Yoder, JW Gage, and GE Roland

Bacterial eradication by clinafloxacin, CI-990, and ciprofloxacin employing MBC test, in-vitro time-kill and in-vivo time-kill studies
J. Antimicrob. Chemother. 1998 41: 605-614; doi:10.1093/jac/41.6.605 [Abstract] [PDF] [Request Permissions]  

EK Manavathu, GJ Alangaden, and PH Chandrasekar

In-vitro isolation and antifungal susceptibility of amphotericin B- resistant mutants of Aspergillus fumigatus
J. Antimicrob. Chemother. 1998 41: 615-619; doi:10.1093/jac/41.6.615 [Abstract] [PDF] [Request Permissions]  

LJ Teng, PR Hsueh, YC Chen, SW Ho, and KT Luh

Antimicrobial susceptibility of viridans group streptococci in Taiwan with an emphasis on the high rates of resistance to penicillin and macrolides in Streptococcus oralis
J. Antimicrob. Chemother. 1998 41: 621-627; doi:10.1093/jac/41.6.621 [Abstract] [PDF] [Request Permissions]  

E Perez-Trallero, M Alkorta, JM Garcia-Arenzana, A Iturzaeta, and M Gomariz

In-vitro, in-vivo and ex-vivo studies with oral beta-lactams against Streptococcus pneumoniae
J. Antimicrob. Chemother. 1998 41: 629-634; doi:10.1093/jac/41.6.629 [Abstract] [PDF] [Request Permissions]  

LJ Piddock, V Ricci, I McLaren, and DJ Griggs

Role of mutation in the gyrA and parC genes of nalidixic-acid-resistant salmonella serotypes isolated from animals in the United Kingdom
J. Antimicrob. Chemother. 1998 41: 635-641; doi:10.1093/jac/41.6.635 [Abstract] [PDF] [Request Permissions]  

SJ Martin and SL Pendland

Bactericidal activity and postantibiotic effect of clarithromycin and 14-hydroxyclarithromycin, alone and in combination, against Legionella pneumophila
J. Antimicrob. Chemother. 1998 41: 643-648; doi:10.1093/jac/41.6.643 [Abstract] [PDF] [Request Permissions]  

JM Hamilton-Miller and S Shah

Comparative in-vitro activity of ketolide HMR 3647 and four macrolides against gram-positive cocci of known erythromycin susceptibility status
J. Antimicrob. Chemother. 1998 41: 649-653; doi:10.1093/jac/41.6.649 [Abstract] [PDF] [Request Permissions]  

B Al-Nawas and PM Shah

Intracellular activity of ciprofloxacin and moxifloxacin, a new 8- methoxyquinolone, against methicillin-resistant Staphylococcus aureus
J. Antimicrob. Chemother. 1998 41: 655-658; doi:10.1093/jac/41.6.655 [Abstract] [PDF] [Request Permissions]  

Letters:

EN Rees and TS Elliott

The influence of bile on antimicrobial activity in vitro
J. Antimicrob. Chemother. 1998 41: 659-660; doi:10.1093/jac/41.6.659 [PDF] [Request Permissions]  

J Blahova, K Kralikova, V Krcmery, D Mlynarcik, and J Trupl

Transduction of imipenem resistance by wild-type bacteriophages carried by three strains of Pseudomonas aeruginosa isolated from a single source
J. Antimicrob. Chemother. 1998 41: 660-662; doi:10.1093/jac/41.6.660 [PDF] [Request Permissions]  

FJ Schmitz, J Verhoef, HP Heinz, and ME Jones

In-vitro activities of quinupristin/dalfopristin and other anti- staphylococcal agents against methicillin-resistant strains of Staphylococcus aureus isolated over a 16-year period
J. Antimicrob. Chemother. 1998 41: 662-664; doi:10.1093/jac/41.6.662 [PDF] [Request Permissions]  

H Mikamo, K Kawazoe, Y Sato, K Izumi, and T Tamaya

In-vitro activity of S-1090, a novel oral cephalosporin, against bacteria causing infections in obstetric and gynaecological patients
J. Antimicrob. Chemother. 1998 41: 664-665; doi:10.1093/jac/41.6.664 [PDF] [Request Permissions]  

N Petit, C Zandotti, JM Riss, F Frippiat, JF Moulin, and JA Gastaut

Relapse of CMV retinitis in an AIDS patient with high CD4 counts
J. Antimicrob. Chemother. 1998 41: 666-667; doi:10.1093/jac/41.6.666 [PDF] [Request Permissions]  

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