Journal of Antimicrobial Chemotherapy

Leading articles:

FR Falkiner

The consequences of antibiotic use in horticulture
J. Antimicrob. Chemother. 1998 41: 429-431; doi:10.1093/jac/41.4.429 [PDF] [Request Permissions]  

Original articles:

RG Finch and R Bax

Clinical trials of antibacterial agents--a commentary
J. Antimicrob. Chemother. 1998 41: 432-434; doi:10.1093/jac/41.4.432 [PDF] [Request Permissions]  

T Horii, M Kobayashi, K Sato, S Ichiyama, and M Ohta

An in-vitro study of carbapenem-induced morphological changes and endotoxin release in clinical isolates of gram-negative bacilli
J. Antimicrob. Chemother. 1998 41: 435-442; doi:10.1093/jac/41.4.435 [Abstract] [PDF] [Request Permissions]  

JD Knudsen, N Frimodt-Moller, and F Espersen

Pharmacodynamics of penicillin are unaffected by bacterial growth phases of Streptococcus pneumoniae in the mouse peritonitis model
J. Antimicrob. Chemother. 1998 41: 451-459; doi:10.1093/jac/41.4.451 [Abstract] [PDF] [Request Permissions]  

P Russell, SM Eley, MJ Fulop, DL Bell, and RW Titball

The efficacy of ciprofloxacin and doxycycline against experimental tularaemia
J. Antimicrob. Chemother. 1998 41: 461-465; doi:10.1093/jac/41.4.461 [Abstract] [PDF] [Request Permissions]  

C Smith, C Burley, M Ireson, T Johnson, D Jordan, S Knight, T Mason, D Massey, J Moss, and K Williams

Clinical trials of antibacterial agents: a practical guide to design and analysis. Statisticians in the Pharmaceutical Industry Working Party
J. Antimicrob. Chemother. 1998 41: 467-480; doi:10.1093/jac/41.4.467 [Abstract] [PDF] [Request Permissions]  

FJ Schmitz, B Hofmann, B Hansen, S Scheuring, M Luckefahr, M Klootwijk, J Verhoef, A Fluit, HP Heinz, K Kohrer, and ME Jones

Relationship between ciprofloxacin, ofloxacin, levofloxacin, sparfloxacin and moxifloxacin (BAY 12-8039) MICs and mutations in grlA, grlB, gyrA and gyrB in 116 unrelated clinical isolates of Staphylococcus aureus
J. Antimicrob. Chemother. 1998 41: 481-484; doi:10.1093/jac/41.4.481 [Abstract] [PDF] [Request Permissions]  

M Dan, F Poch, A Edelman, J Asherov, H Hafely, and Y Atzmon

Serum bactericidal activity of newer oral cephalosporins in healthy volunteers
J. Antimicrob. Chemother. 1998 41: 485-488; doi:10.1093/jac/41.4.485 [Abstract] [PDF] [Request Permissions]  

I Brook and AE Gober

Bacterial interference in the nasopharynx following antimicrobial therapy of acute otitis media
J. Antimicrob. Chemother. 1998 41: 489-492; doi:10.1093/jac/41.4.489 [Abstract] [PDF] [Request Permissions]  

Reviews:

D Pierard, K Emmerechts, and S Lauwers

Comparative in-vitro activity of cefpirome against isolates from intensive care and haematology/oncology units. Belgian Multicentre Study Group
J. Antimicrob. Chemother. 1998 41: 443-450; doi:10.1093/jac/41.4.443 [Abstract] [PDF] [Request Permissions]  

Letters:

JL Munoz Bellido and JA Garcia-Rodriguez

Aztreonam-clavulanic acid synergy does not mean extended-spectrum beta- lactamase in Stenotrophomonas maltophilia
J. Antimicrob. Chemother. 1998 41: 493-494; doi:10.1093/jac/41.4.493 [PDF] [Request Permissions]  

GM Hogg, JG Barr, and CH Webb

In-vitro activity of the combination of colistin and rifampicin against multidrug-resistant strains of Acinetobacter baumannii [published erratum appears in J Antimicrob Chemother 1998 Sep;42(3):413]
J. Antimicrob. Chemother. 1998 41: 494-495; doi:10.1093/jac/41.4.494 [PDF] [Request Permissions]  

S Fujimura, Y Tokue, H Takahashi, T Nukiwa, K Hisamichi, T Mikami, and A Watanabe

A newly recognized acetylated metabolite of arbekacin in arbekacin- resistant strains of methicillin-resistant Staphylococcus aureus
J. Antimicrob. Chemother. 1998 41: 495-497; doi:10.1093/jac/41.4.495 [PDF] [Request Permissions]  

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