Journal of Antimicrobial Chemotherapy

Leading articles:

P Venkatesan

Albendazole
J. Antimicrob. Chemother. 1998 41: 145-147; doi:10.1093/jac/41.2.145 [PDF] [Request Permissions]  

Original articles:

FJ Boswell, JM Andrews, and R Wise

Pharmacodynamic properties of HMR 3647, a novel ketolide, on respiratory pathogens, enterococci and Bacteroides fragilis demonstrated by studies of time-kill kinetics and postantibiotic effect
J. Antimicrob. Chemother. 1998 41: 149-153; doi:10.1093/jac/41.2.149 [Abstract] [PDF] [Request Permissions]  

ME Rupp and KE Hamer

Effect of subinhibitory concentrations of vancomycin, cefazolin, ofloxacin, L-ofloxacin and D-ofloxacin on adherence to intravascular catheters and biofilm formation by Staphylococcus epidermidis
J. Antimicrob. Chemother. 1998 41: 155-161; doi:10.1093/jac/41.2.155 [Abstract] [PDF] [Request Permissions]  

M Trautmann, R Zick, T Rukavina, AS Cross, and R Marre

Antibiotic-induced release of endotoxin: in-vitro comparison of meropenem and other antibiotics
J. Antimicrob. Chemother. 1998 41: 163-169; doi:10.1093/jac/41.2.163 [Abstract] [PDF] [Request Permissions]  

P Kaihovaara, J Hook-Nikanne, M Uusi-Oukari, TU Kosunen, and M Salaspuro

Flavodoxin-dependent pyruvate oxidation, acetate production and metronidazole reduction by Helicobacter pylori
J. Antimicrob. Chemother. 1998 41: 171-177; doi:10.1093/jac/41.2.171 [Abstract] [PDF] [Request Permissions]  

F Doucet-Populaire, JO Capobianco, D Zakula, V Jarlier, and RC Goldman

Molecular basis of clarithromycin activity against Mycobacterium avium and Mycobacterium smegmatis
J. Antimicrob. Chemother. 1998 41: 179-187; doi:10.1093/jac/41.2.179 [Abstract] [PDF] [Request Permissions]  

H Weindorf, H Schmidt, and HH Martin

Contribution of overproduced chromosomal beta-lactamase and defective outer membrane porins to resistance to extended-spectrum beta-lactam antibiotics in Serratia marcescens
J. Antimicrob. Chemother. 1998 41: 189-195; doi:10.1093/jac/41.2.189 [Abstract] [PDF] [Request Permissions]  

A Liendo, K Lazardi, and JA Urbina

In-vitro antiproliferative effects and mechanism of action of the bis- triazole D0870 and its S(-) enantiomer against Trypanosoma cruzi
J. Antimicrob. Chemother. 1998 41: 197-205; doi:10.1093/jac/41.2.197 [Abstract] [PDF] [Request Permissions]  

LB Quesnel, AS Jaran, and JM Braganza

Antibiotic accumulation and membrane trafficking in cystic fibrosis cells
J. Antimicrob. Chemother. 1998 41: 215-221; doi:10.1093/jac/41.2.215 [Abstract] [PDF] [Request Permissions]  

JH Kim, KH Choi, JW Kim, JH Lee, EC Choi, and BK Kim

In-vitro and in-vivo antibacterial activity of CFC-222, a new fluoroquinolone
J. Antimicrob. Chemother. 1998 41: 223-229; doi:10.1093/jac/41.2.223 [Abstract] [PDF] [Request Permissions]  

AF Goddard, PO Erah, DA Barrett, PN Shaw, and RC Spiller

The effect of protein binding and lipophilicity of penicillins on their in-vitro flux across gastric mucosa
J. Antimicrob. Chemother. 1998 41: 231-236; doi:10.1093/jac/41.2.231 [Abstract] [PDF] [Request Permissions]  

P Chavanet, F Dalle, P Delisle, M Duong, A Pechinot, M Buisson, P D'Athis, and H Portier

Experimental efficacy of combined ceftriaxone and amoxycillin on penicillin-resistant and broad-spectrum cephalosporin-resistant Streptococcus pneumoniae infection
J. Antimicrob. Chemother. 1998 41: 237-246; doi:10.1093/jac/41.2.237 [Abstract] [PDF] [Request Permissions]  

YF Chiew, SF Yeo, LM Hall, and DM Livermore

Can susceptibility to an antimicrobial be restored by halting its use? The case of streptomycin versus Enterobacteriaceae
J. Antimicrob. Chemother. 1998 41: 247-251; doi:10.1093/jac/41.2.247 [Abstract] [PDF] [Request Permissions]  

H Dabernat, P Geslin, F Megraud, P Begue, J Boulesteix, C Dubreuil, F de La Roque, A Trinh, and A Scheimberg

Effects of cefixime or co-amoxiclav treatment on nasopharyngeal carriage of Streptococcus pneumoniae and Haemophilus influenzae in children with acute otitis media
J. Antimicrob. Chemother. 1998 41: 253-258; doi:10.1093/jac/41.2.253 [Abstract] [PDF] [Request Permissions]  

G Mazzaglia, S Greco, C Lando, G Cucinotta, and AP Caputi

Adult acute upper respiratory tract infections in Sicily: pattern of antibiotic drug prescription in primary care
J. Antimicrob. Chemother. 1998 41: 259-266; doi:10.1093/jac/41.2.259 [Abstract] [PDF] [Request Permissions]  

A Sasse, R Mertens, JP Sion, O Ronveaux, M Bossens, P De Mol, H Goossens, S Lauwers, C Potvliege, H Van Landuyt, L Verbist, and G Verschraegen

Surgical prophylaxis in Belgian hospitals: estimate of costs and potential savings
J. Antimicrob. Chemother. 1998 41: 267-272; doi:10.1093/jac/41.2.267 [Abstract] [PDF] [Request Permissions]  

S Harland, SE Tebbs, and TS Elliott

Evaluation of the in-vitro activity of the glycopeptide antibiotic LY333328 in comparison with vancomycin and teicoplanin
J. Antimicrob. Chemother. 1998 41: 273-276; doi:10.1093/jac/41.2.273 [Abstract] [PDF] [Request Permissions]  

JM Rajyaguru and MJ Muszynski

Sensitization of Burkholderia cepacia to antibiotics by cationic drugs
J. Antimicrob. Chemother. 1998 41: 277-280; doi:10.1093/jac/41.2.277 [Abstract] [PDF] [Request Permissions]  

MA Nasher and RJ Hay

Synergy of antibiotics against Streptomyces somaliensis isolates in vitro
J. Antimicrob. Chemother. 1998 41: 281-284; doi:10.1093/jac/41.2.281 [Abstract] [PDF] [Request Permissions]  

ME Evans and WB Titlow

Levofloxacin selects fluoroquinolone-resistant methicillin-resistant Staphylococcus aureus less frequently than ciprofloxacin
J. Antimicrob. Chemother. 1998 41: 285-288; doi:10.1093/jac/41.2.285 [Abstract] [PDF] [Request Permissions]  

JE Stout, B Arnold, and VL Yu

Activity of azithromycin, clarithromycin, roxithromycin, dirithromycin, quinupristin/dalfopristin and erythromycin against Legionella species by intracellular susceptibility testing in HL-60 cells
J. Antimicrob. Chemother. 1998 41: 289-291; doi:10.1093/jac/41.2.289 [Abstract] [PDF] [Request Permissions]  

X You, RF Schinazi, MJ Arrowood, M Lejkowski, AS Juodawlkis, and JR Mead

In-vitro activities of paromomycin and lasalocid evaluated in combination against Cryptosporidium parvum
J. Antimicrob. Chemother. 1998 41: 293-296; doi:10.1093/jac/41.2.293 [Abstract] [PDF] [Request Permissions]  

B Robibaro, H Vorbach, G Weigel, A Weihs, M Hlousek, E Presterl, A Georgopoulos, A Griesmacher, and W Graninger

Endothelial cell compatibility of glycopeptide antibiotics for intravenous use
J. Antimicrob. Chemother. 1998 41: 297-300; doi:10.1093/jac/41.2.297 [Abstract] [PDF] [Request Permissions]  

P Russell, SM Eley, M Green, AJ Stagg, RR Taylor, M Nelson, RJ Beedham, DL Bell, D Rogers, D Whittington, and RW Titball

Efficacy of doxycycline and ciprofloxacin against experimental Yersinia pestis infection
J. Antimicrob. Chemother. 1998 41: 301-305; doi:10.1093/jac/41.2.301 [Abstract] [PDF] [Request Permissions]  

G Bonfiglio, V Carciotto, G Russo, S Stefani, GC Schito, E Debbia, and G Nicoletti

Antibiotic resistance in Pseudomonas aeruginosa: an Italian survey
J. Antimicrob. Chemother. 1998 41: 307-310; doi:10.1093/jac/41.2.307 [Abstract] [PDF] [Request Permissions]  

Reviews:

MP Richard, AG Aguado, R Mattina, and R Marre

Sensitivity to sparfloxacin and other antibiotics, of Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis strains isolated from adult patients with community-acquired lower respiratory tract infections: a European multicentre study. SPAR Study Group. Surveillance Programme of Antibiotic Resistance
J. Antimicrob. Chemother. 1998 41: 207-214; doi:10.1093/jac/41.2.207 [Abstract] [PDF] [Request Permissions]  

Letters:

FJ Schmitz, J Verhoef, A Fluit, HP Heinz, and ME Jones

Stability of the MICs of various antibiotics in different clonal populations of methicillin-resistant Staphylococcus aureus
J. Antimicrob. Chemother. 1998 41: 311-313; doi:10.1093/jac/41.2.311 [PDF] [Request Permissions]  

G Danelon, O Mascaretti, M Radice, P Power, ML Calcagno, EG Mata, and G Gutkind

Comparative in-vitro activities of GD-40 and other beta-lactamase inhibitors against TEM-1 and SHV-2 beta-lactamases
J. Antimicrob. Chemother. 1998 41: 313-315; doi:10.1093/jac/41.2.313 [PDF] [Request Permissions]  

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