Journal of Antimicrobial Chemotherapy

Leading articles:

EM Brown

Empirical antimicrobial therapy of mechanically ventilated patients with nosocomial pneumonia
J. Antimicrob. Chemother. 1997 40: 463-468; doi:10.1093/jac/40.4.463 [PDF] [Request Permissions]  

Reviews:

M Denton and MH Wilcox

Antimicrobial treatment of pulmonary colonization and infection by pseudomonas aeruginosa in cystic fibrosis patients
J. Antimicrob. Chemother. 1997 40: 468-474; doi:10.1093/jac/40.4.468 [PDF] [Request Permissions]  

WN Hustinx, K Kraaijeveld, AI Hoepelman, and J Verhoef

Cross-protection by anti-core glycolipid antibodies: evidence from animal experiments
J. Antimicrob. Chemother. 1997 40: 475-483; doi:10.1093/jac/40.4.475 [Abstract] [PDF] [Request Permissions]  

Original articles:

GA Eby

Zinc ion availability--the determinant of efficacy in zinc lozenge treatment of common colds
J. Antimicrob. Chemother. 1997 40: 483-493. [Abstract] [Request Permissions]  

IM Gould and FM MacKenzie

The response of Enterobacteriaceae to beta-lactam antibiotics--'round forms, filaments and the root of all evil'
J. Antimicrob. Chemother. 1997 40: 495-499; doi:10.1093/jac/40.4.495 [PDF] [Request Permissions]  

D Greenwood

Antibiotic effects in vitro and the prediction of clinical response
J. Antimicrob. Chemother. 1997 40: 499-501; doi:10.1093/jac/40.4.499 [PDF] [Request Permissions]  

AP MacGowan, KE Bowker, HA Holt, M Wootton, and DS Reeves

Bay 12-8039, a new 8-methoxy-quinolone: comparative in-vitro activity with nine other antimicrobials against anaerobic bacteria
J. Antimicrob. Chemother. 1997 40: 503-509; doi:10.1093/jac/40.4.503 [Abstract] [PDF] [Request Permissions]  

JL May, A King, and CA Warren

Fluconazole disc diffusion testing for the routine laboratory
J. Antimicrob. Chemother. 1997 40: 511-516; doi:10.1093/jac/40.4.511 [Abstract] [PDF] [Request Permissions]  

JD Cartledge, J Midgley, M Petrou, D Shanson, and BG Gazzard

Unresponsive HIV-related oro-oesophageal candidosis--an evaluation of two new in-vitro azole susceptibility tests
J. Antimicrob. Chemother. 1997 40: 517-523; doi:10.1093/jac/40.4.517 [Abstract] [PDF] [Request Permissions]  

X Xiang, K Shannon, and G French

Mechanism and stability of hyperproduction of the extended-spectrum beta-lactamase SHV-5 in Klebsiella pneumoniae
J. Antimicrob. Chemother. 1997 40: 525-532; doi:10.1093/jac/40.4.525 [Abstract] [PDF] [Request Permissions]  

R Gheorghiu, M Yuan, LM Hall, and DM Livermore

Bases of variation in resistance to beta-lactams in Klebsiella oxytoca isolates hyperproducing K1 beta-lactamase
J. Antimicrob. Chemother. 1997 40: 533-541; doi:10.1093/jac/40.4.533 [Abstract] [PDF] [Request Permissions]  

T Deguchi, M Yasuda, M Nakano, S Ozeki, E Kanematsu, Y Nishino, S Ishihara, and Y Kawada

Detection of mutations in the gyrA and parC genes in quinolone- resistant clinical isolates of Enterobacter cloacae
J. Antimicrob. Chemother. 1997 40: 543-549; doi:10.1093/jac/40.4.543 [Abstract] [PDF] [Request Permissions]  

Z Leng, DE Riley, RE Berger, JN Krieger, and MC Roberts

Distribution and mobility of the tetracycline resistance determinant tetQ
J. Antimicrob. Chemother. 1997 40: 551-559; doi:10.1093/jac/40.4.551 [Abstract] [PDF] [Request Permissions]  

R Huang, DM Gascoyne-Binzi, PM Hawkey, M Yu, J Heritage, and A Eley

Molecular evolution of the tet(M) gene in Gardnerella vaginalis
J. Antimicrob. Chemother. 1997 40: 561-565; doi:10.1093/jac/40.4.561 [Abstract] [PDF] [Request Permissions]  

WN Hustinx, BJ Benaissa-Trouw, T Harmsen, S Klein, J Verhoef, AI Hoepelman, and K Kraaijeveld

Evaluation of protection by two endotoxin-neutralizing IgM monoclonal antibodies in different peritonitis models
J. Antimicrob. Chemother. 1997 40: 567-572; doi:10.1093/jac/40.4.567 [Abstract] [PDF] [Request Permissions]  

JM Andrews, D Honeybourne, G Jevons, NP Brenwald, B Cunningham, and R Wise

Concentrations of levofloxacin (HR 355) in the respiratory tract following a single oral dose in patients undergoing fibre-optic bronchoscopy
J. Antimicrob. Chemother. 1997 40: 573-577; doi:10.1093/jac/40.4.573 [Abstract] [PDF] [Request Permissions]  

H Young, A Moyes, and C Hardie

Failure of Neisseria gonorrhoeae to grow in the ATB NH susceptibility test system
J. Antimicrob. Chemother. 1997 40: 579-582; doi:10.1093/jac/40.4.579 [Abstract] [PDF] [Request Permissions]  

O Cirioni, A Giacometti, M Quarta, and G Scalise

In-vitro activity of topoisomerase inhibitors against Pneumocystis carinii
J. Antimicrob. Chemother. 1997 40: 583-586; doi:10.1093/jac/40.4.583 [Abstract] [PDF] [Request Permissions]  

M Wainwright, DA Phoenix, J Marland, DR Wareing, and FJ Bolton

In-vitro photobactericidal activity of aminoacridines
J. Antimicrob. Chemother. 1997 40: 587-589; doi:10.1093/jac/40.4.587 [Abstract] [PDF] [Request Permissions]  

TG Winstanley, DI Limb, R Eggington, and F Hancock

A 10 year survey of the antimicrobial susceptibility of urinary tract isolates in the UK: the Microbe Base project
J. Antimicrob. Chemother. 1997 40: 591-594; doi:10.1093/jac/40.4.591 [Abstract] [PDF] [Request Permissions]  

CH Steffee, RM Morrell, and BL Wasilauskas

Clinical use of rifampicin during routine reporting of rifampicin susceptibilities: a lesson in selective reporting of antimicrobial susceptibility data
J. Antimicrob. Chemother. 1997 40: 595-598; doi:10.1093/jac/40.4.595 [Abstract] [PDF] [Request Permissions]  

Letters:

M Chomarat, L Chollet, M Peyret, and JP Flandrois

Influence of atmospheric conditions during incubation on the susceptibilities of Streptococcus pneumoniae isolates to five beta- lactam antibiotics
J. Antimicrob. Chemother. 1997 40: 599-601; doi:10.1093/jac/40.4.599 [PDF] [Request Permissions]  

RK Budhani and JK Struthers

The use of Sorbarod biofilms to study the antimicrobial susceptibility of a strain of Streptococcus pneumoniae
J. Antimicrob. Chemother. 1997 40: 601-602; doi:10.1093/jac/40.4.601 [PDF] [Request Permissions]  

S van Niekerk, F Huygens, and CE van Rensburg

A time-kill study to evaluate the in-vitro activity of clofazimine in combination with cefotaxime against a penicillin- and cefotaxime- resistant strain of Streptococcus pneumoniae
J. Antimicrob. Chemother. 1997 40: 602-604; doi:10.1093/jac/40.4.602 [PDF] [Request Permissions]  

AP Johnson, M Warner, and DC Speller

In-vitro activity of quinupristin/dalfopristin (Synercid) against isolates of Streptococcus pneumoniae, Staphylococcus aureus and enterococcus spp
J. Antimicrob. Chemother. 1997 40: 604-605; doi:10.1093/jac/40.4.604 [PDF] [Request Permissions]  

F Marco, MS Barrett, and RN Jones

Antimicrobial activity of LB20304, a fluoronaphthyridone, tested against anaerobic bacteria
J. Antimicrob. Chemother. 1997 40: 605-607; doi:10.1093/jac/40.4.605 [PDF] [Request Permissions]  

EA Rizkalla, JE Moore, SA Marshall, and PG Murphy

Glycopeptide-resistant enterococci in Northern Ireland: first reported outbreak
J. Antimicrob. Chemother. 1997 40: 607-608; doi:10.1093/jac/40.4.607 [PDF] [Request Permissions]  

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