Journal of Antimicrobial Chemotherapy

Leading articles:

JANE H. LANGFORD and SHALOM I. BENRIMOJ

Clinical rationale for topical antimicrobial preparations
J. Antimicrob. Chemother. 1996 37: 399-402; doi:10.1093/jac/37.3.399 [PDF] [Request Permissions]  

Review:

David W. Kimberlin and Richard J. Whitley

Antiviral resistance: mechanisms, clinical significance, and future implications
J. Antimicrob. Chemother. 1996 37: 403-421; doi:10.1093/jac/37.3.403 [Abstract] [PDF] [Request Permissions]  

Original articles:

Timothy R. Walsh, Steven Gamblin, David C. Emery, Alasdair P. MacGowan, and Peter M. Bennett

Enzyme kinetics and biochemical analysis of ImiS, the metallo-ß-lactamase from Aeromonas sobria 163a
J. Antimicrob. Chemother. 1996 37: 423-431; doi:10.1093/jac/37.3.423 [Abstract] [PDF] [Request Permissions]  

S. Minami, H. Akama, Y. Watanabe, H. Narita, S. Iyobe, and S. Mitsuhashi

Imipenem and cephem resistant Pseudomonas aeruginosa carrying plasmids coding for class B ß-lactamase
J. Antimicrob. Chemother. 1996 37: 433-444; doi:10.1093/jac/37.3.433 [Abstract] [PDF] [Request Permissions]  

A. C. Petersson, H. Miörner, and C. Kamme

Identification of mecA-related oxacillin resistance in staphylococci by the E test and the broth microdilution method
J. Antimicrob. Chemother. 1996 37: 445-456; doi:10.1093/jac/37.3.445 [Abstract] [PDF] [Request Permissions]  

D. E. Roe, A. Weinberg, and M. C. Roberts

Mobile rRNA methylase genes coding for erythromycin resistance in Actinobacillus actinomycetemcomitans
J. Antimicrob. Chemother. 1996 37: 457-464; doi:10.1093/jac/37.3.457 [Abstract] [PDF] [Request Permissions]  

T. K. C. Ng, R. C. Y. Chan, F. A. B. Adeyemi-Doro, S. W. Cheung, and A. F. B. Cheng

Rapid high performance liquid chromatographic assay for antifungal agents in human sera
J. Antimicrob. Chemother. 1996 37: 465-472; doi:10.1093/jac/37.3.465 [Abstract] [PDF] [Request Permissions]  

Hua-Xiang Xia, Martin Buckley, Conor T. Keane, and Colm A. O'Morain

Clarithromycin resistance in Helicobacter pylori: prevalence in untreated dyspeptic patients and stability in vitro
J. Antimicrob. Chemother. 1996 37: 473-481; doi:10.1093/jac/37.3.473 [Abstract] [PDF] [Request Permissions]  

Kristina Hultén, Otto Cars, Eva Hjelm, and Lars Engstrand

In-vitro activity of azithromycin against intracellular Helicobacter pylori
J. Antimicrob. Chemother. 1996 37: 483-489; doi:10.1093/jac/37.3.483 [Abstract] [PDF] [Request Permissions]  

Hiroe Shiratsuchi, Michael R. Jacobs, Anthony J. Pearson, Nandagopal Venkataprasad, Gilles Klopman, and Jerrold Ellner

Comparison of the activity of fluoroquinolones against Mycobacterium avium in cell-free systems and a human monocyte in-vitro infection model
J. Antimicrob. Chemother. 1996 37: 491-500; doi:10.1093/jac/37.3.491 [Abstract] [PDF] [Request Permissions]  

Isabelle Pellegrin, Jeanne Maugein, Catherine Lapeyre, Pascal Barbeau, Bernard Leng, and Jean-Luc Pellegrin

Activity of rifabutin, clarithromycin, ethambutol, sparfloxacin and amikacin, alone and in combination, against Mycobacterium avium complex in human macrophages
J. Antimicrob. Chemother. 1996 37: 501-510; doi:10.1093/jac/37.3.501 [Abstract] [PDF] [Request Permissions]  

E. I. Elueze, S. L. Croft, and D. C. Warhurst

Activity of pyronaridine and mepacrine against twelve strains of Plasmodium falciparum in vitro
J. Antimicrob. Chemother. 1996 37: 511-518; doi:10.1093/jac/37.3.511 [Abstract] [PDF] [Request Permissions]  

P. Legrand, A. Vertut-Doi, and J. Bolard

Comparative internalization and recycling of different amphotericin B formulations by a macrophage-like cell line
J. Antimicrob. Chemother. 1996 37: 519-533; doi:10.1093/jac/37.3.519 [Abstract] [PDF] [Request Permissions]  

Myra A. Arnott, John Hay, and John F. Peutherer

HIV-induced cytopathology and viral load in a pentamidine-treated lymphocytic cell line
J. Antimicrob. Chemother. 1996 37: 535-543; doi:10.1093/jac/37.3.535 [Abstract] [PDF] [Request Permissions]  

J. A. Steer, R. P. G. Papini, A. P. R. Wilson, S. Dhillon, M. F. Hichens, D. A. McGrouther, J. D. Frame, and N. Parkhouse

Pharmacokinetics of a single dose of teicoplanin in burn patients
J. Antimicrob. Chemother. 1996 37: 545-553; doi:10.1093/jac/37.3.545 [Abstract] [PDF] [Request Permissions]  

Francisco Higuera, Hilda Hidalgo, Jesus Feris, Gregory Giguere, and Jeffrey J. Collins

Comparison of oral cefuroxime axetil and oral amoxycillin/clavulanate in the treatment of community-acquired pneumonia
J. Antimicrob. Chemother. 1996 37: 555-564; doi:10.1093/jac/37.3.555 [Abstract] [PDF] [Request Permissions]  

G. J. Fernández MacLoughlin, D. Gomez Barreto, C. de la Torre, E. A. Pinetta, F. del Castillo, and L. Palma

Cefpodoxime proxetil suspension compared with cefaclor suspension for treatment of acute otitis media in paediatric patients
J. Antimicrob. Chemother. 1996 37: 565-573; doi:10.1093/jac/37.3.565 [Abstract] [PDF] [Request Permissions]  

D. Dutta, S. K. Bhattacharya, M. K. Bhattacharya, A. Deb, M. Deb, B. Manna, A. Moitra, A. K. Mukhopadhyay, and G. B. Nair

Efficacy of norfloxacin and doxycycline for treatment of Vibrio cholerae O139 infection
J. Antimicrob. Chemother. 1996 37: 575-581; doi:10.1093/jac/37.3.575 [Abstract] [PDF] [Request Permissions]  

R. W. Peck, P. Crome, M. J. Wood, M. W. McKendrick, B. Bannister, B. K. Mandal, and R. J. Crooks

Multiple dose netivudine, a potent anti-varicella zoster virus agent, in healthy elderly volunteers and patients with shingles
J. Antimicrob. Chemother. 1996 37: 583-597; doi:10.1093/jac/37.3.583 [Abstract] [PDF] [Request Permissions]  

Brief reports:

Carl Lawyer, Sudha Pai, Misako Watabe, Haithem Bakir, Lanie Eagleton, and Kounosuke Watabe

Effects of synthetic form of tracheal antimicrobial peptide on respiratory pathogens
J. Antimicrob. Chemother. 1996 37: 599-604; doi:10.1093/jac/37.3.599 [Abstract] [PDF] [Request Permissions]  

Noboru Tsuchimori and Kenji Okonogi

Penicillin-binding protein 5 as an inhibitory target of cefozopran in Enterococcus faecalis
J. Antimicrob. Chemother. 1996 37: 605-609; doi:10.1093/jac/37.3.605 [Abstract] [PDF] [Request Permissions]  

M. D. Smith, V. Wuthiekanun, A. L. Walsh, and N. J. White

n-vitro activity of carbapenem antibiotics against ß-lactam susceptible and resistant strains of Burkholderia pseudomallei
J. Antimicrob. Chemother. 1996 37: 611-615; doi:10.1093/jac/37.3.611 [Abstract] [PDF] [Request Permissions]  

Marta Feldmesser, Jean Mukherjee, and Arturo Casadevall

Combination of 5-flucytosine and capsule-binding monoclonal antibody in the treatment of murine Cryptococcus neoformans infections and in vitro
J. Antimicrob. Chemother. 1996 37: 617-622; doi:10.1093/jac/37.3.617 [Abstract] [PDF] [Request Permissions]  

Antimicrobial practice:

Peter G. Davey, Richard South, and Mo Malek

Impact of glycopeptide therapy after hospital discharge on inpatient costs: a comparison of teicoplanin and vancomycin
J. Antimicrob. Chemother. 1996 37: 623-633; doi:10.1093/jac/37.3.623 [Abstract] [PDF] [Request Permissions]  

Correspondence:

D. DE AMICI, F. RAMAIOLI, P. CERIANA, and E. PERCIVALLE

Antiviral activity of local anaesthetic agents
J. Antimicrob. Chemother. 1996 37: 635; doi:10.1093/jac/37.3.635 [PDF] [Request Permissions]  

I. M. GOULD, D. SHEPHERD, and G. WILSON

Over-the-counter availability of antibiotics
J. Antimicrob. Chemother. 1996 37: 635-636; doi:10.1093/jac/37.3.635-a [PDF] [Request Permissions]  

R. EDWARDS, D. THIRLWELL, and D. GREENWOOD

Changes in ß-lactam antibiotic susceptibility and ß-lactamase production of clinical isolates of Bacleroides and Prevotella species over a 9 year period
J. Antimicrob. Chemother. 1996 37: 636-638; doi:10.1093/jac/37.3.636 [PDF] [Request Permissions]  

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