Journal of Antimicrobial Chemotherapy

Leading articles:

B. RUF and J. SANDFORT

Human microsporidiosis: J Antimicrob Chemother 1994, 34: 609–611
J. Antimicrob. Chemother. 1994 34: 609-611; doi:10.1093/jac/34.5.609 [PDF] [Request Permissions]  

Review:

R. S. Pore

Antibiotic susceptibility testing by flow cytometry
J. Antimicrob. Chemother. 1994 34: 613-627; doi:10.1093/jac/34.5.613 [Abstract] [PDF] [Request Permissions]  

Original articles:

R. Wise, J. M. Andrews, and D. Thornber

The in-vitro activity of FK-037, a new broad spectrum injectable cephalosporin
J. Antimicrob. Chemother. 1994 34: 629-637; doi:10.1093/jac/34.5.629 [Abstract] [PDF] [Request Permissions]  

S. G. B. Amyes, D. R. Baird, D. W. Crook, S. H. Gillesple, A. J. Howard, B. A. Oppenhiem, S. J. Pedler, A. Paull, D. S. Tompkins, and S. A. Lawrie

A multicentre study of the in-vitro activity of cefotaxime, cefuroxime, ceftazidime, ofloxacin and ciprofloxacin against blood and urinary pathogens
J. Antimicrob. Chemother. 1994 34: 639-648; doi:10.1093/jac/34.5.639 [Abstract] [PDF] [Request Permissions]  

P. Olliaro, G. Gorini, D. Jabes, A. Regazzetti, R. Rossi, A. Marchetti, C. Tinelli, and C. Della Bruna

In-vitro and in-vivo activity of rifabutin against Toxoplasma gondii
J. Antimicrob. Chemother. 1994 34: 649-657; doi:10.1093/jac/34.5.649 [Abstract] [PDF] [Request Permissions]  

D. Law, C. B. Moore, H. M. Wardle, L. A. Ganguli, M. G. L. Keaney, and D. W. Denning

High prevalence of antifungal resistance in Candida spp. from patients with AIDS
J. Antimicrob. Chemother. 1994 34: 659-668; doi:10.1093/jac/34.5.659 [Abstract] [PDF] [Request Permissions]  

A. C. Jason, F. M. MacKenzie, D. Jason, and I. M. Gould

Automatic procedures for measuring post-antibiotic effect and determining random errors
J. Antimicrob. Chemother. 1994 34: 669-678; doi:10.1093/jac/34.5.669 [Abstract] [PDF] [Request Permissions]  

Amparo Pastor, Javier Pemán, and Emilia Cantón

In-vitro postantibiotic effect of sparfloxacin and ciprofloxacin against Pseudomonas aeruginosa and Enterococcus faecalis
J. Antimicrob. Chemother. 1994 34: 679-685; doi:10.1093/jac/34.5.679 [Abstract] [PDF] [Request Permissions]  

K. Kikuchi, T. Enari, S. Minami, K. Haruki, Y. Shibata, H. Hasegawa, J. Katahira K. Totsuka, and K. Shimizu

Postantibiotic effects and postantibiotic sub-MIC effects of benzylpenicillin on viridans streptococci isolated from patients with infective endocarditis
J. Antimicrob. Chemother. 1994 34: 687-696; doi:10.1093/jac/34.5.687 [Abstract] [PDF] [Request Permissions]  

C. Henquell, D. Sirot, C. Chanal, C. De Champs, P. Chatron, B. Lafeuille, P. Texier, J. Sirof, and R. Cluzel

Frequency of inhibitor-resistant TEM ß-lactamases in Escherichia coli isolates from urinary tract infections in Fran
J. Antimicrob. Chemother. 1994 34: 707-714; doi:10.1093/jac/34.5.707 [Abstract] [PDF] [Request Permissions]  

Hilary-Kay Young, M. J. Qumsieh, and M. Louise Mclntosh

Nucleotide sequence and genetic analysis of the type Ib trimethoprim-resistant, Tn4132-encoded dihydrofolate reductase
J. Antimicrob. Chemother. 1994 34: 715-725; doi:10.1093/jac/34.5.715 [Abstract] [PDF] [Request Permissions]  

C. Contini, M. Manganaro, R. Romani, S. Tzantzoglou, I. Poggesi, V. Vullo, S. Delia, and C. De Simone

Activity of terbinafine against Pneumocystis carinii in vitro and its efficacy in the treatment of experimental pneumonia
J. Antimicrob. Chemother. 1994 34: 727-735; doi:10.1093/jac/34.5.727 [Abstract] [PDF] [Request Permissions]  

Y. Tsutomi, K. Matsubayashi, and K. Akabane

Quantitation of GABA_A receptor inhibition required for quinolone-induced convulsions in mice
J. Antimicrob. Chemother. 1994 34: 737-746; doi:10.1093/jac/34.5.737 [Abstract] [PDF] [Request Permissions]  

H. A. Holt, L. O. White, K. A. Bedford, K. E. Bowker, D. S. Reeves, and A. P. MacGowan

An evaluation of three new immunoassays for determination of serum gentamicin concentrations
J. Antimicrob. Chemother. 1994 34: 747-754; doi:10.1093/jac/34.5.747 [Abstract] [PDF] [Request Permissions]  

J. Gisby, A. S. Beale, J. E. Bryant, and C. D. N. Toseland

Staphylococcal osteomyelitis—a comparison of co-amoxiclav with clindamycin and flucloxacillin in an experimental rat model
J. Antimicrob. Chemother. 1994 34: 755-764; doi:10.1093/jac/34.5.755 [Abstract] [PDF] [Request Permissions]  

Jane E. Raulston

Pharmacokinetics of azithromycin and erythromycin in human endometrial epithelial cells and in cells infected with Chlamydia trachomatis
J. Antimicrob. Chemother. 1994 34: 765-776; doi:10.1093/jac/34.5.765 [Abstract] [PDF] [Request Permissions]  

Articles:

K. Gensberg, E. J. Doyle, D. J. Perry, and A. W. Smith

Uptake of BRL 41897A, a C(7) -formamido substituted cephalosporin, via the ferri-pyochelin transport system of Pseudomonas aeruginosa
J. Antimicrob. Chemother. 1994 34: 697-705; doi:10.1093/jac/34.5.697 [Abstract] [PDF] [Request Permissions]  

Brief reports:

E. E. Stobberingh, D. M. Maclaren, P. I. M. Schmitz, and The Multicentre Study Group

Comparative in-vitro activity of piperacillin-tazobactam against recent clinical isolates, a Dutch national multicentre study
J. Antimicrob. Chemother. 1994 34: 777-783; doi:10.1093/jac/34.5.777 [Abstract] [PDF] [Request Permissions]  

B. Cassinat and M. H. Nicolas

Comparison of antibiotic combinations against penicillin-resistant pneumococci
J. Antimicrob. Chemother. 1994 34: 785-790; doi:10.1093/jac/34.5.785 [Abstract] [PDF] [Request Permissions]  

Itzhak Brook

Comparison of cefoxitin, cefotetan and the combination of ampicillin with sulbactam in the therapy of polymicrobial infection in mice
J. Antimicrob. Chemother. 1994 34: 791-796; doi:10.1093/jac/34.5.791 [Abstract] [PDF] [Request Permissions]  

John M. Quale, David Landman, and Neville Mobarakai

Treatment of experimental endocarditis due to multidrug resistant Enterococcus faecium with ciprofloxacin and novobiocin
J. Antimicrob. Chemother. 1994 34: 797-802; doi:10.1093/jac/34.5.797 [Abstract] [PDF] [Request Permissions]  

E. Pussard, D. Chassard, F. Clavier, Ph. Bry, and F. Verdier

Pharmacokinetics and metabolism of amopyroquin after administration of two doses of 6 mg/kg im 24 h apart to healthy volunteers
J. Antimicrob. Chemother. 1994 34: 803-808; doi:10.1093/jac/34.5.803 [Abstract] [PDF] [Request Permissions]  

A. P. MacGowan, K. A. Bedford, E. Blundell, N. M. Brown, F. Habib, J. Hows, B. Kirkpatrick, R. J. Korner, R. R. Slade, L. O. White, and D. S. Reeves

The pharmacokinetics of once daily gentamicin in neutropenic adults with haematological malignancy
J. Antimicrob. Chemother. 1994 34: 809-812; doi:10.1093/jac/34.5.809 [Abstract] [PDF] [Request Permissions]  

Harry Scheinin, Tapani Havia, Erkki Pekkala, Pentti Huovinen, Jorma Klossner, Heikki Lehto, and Juha Niinikoski

Aspoxicillin versus piperacillin in severe abdominal infections— a comparative phase III study
J. Antimicrob. Chemother. 1994 34: 813-817; doi:10.1093/jac/34.5.813 [Abstract] [PDF] [Request Permissions]  

Antimicrobial practice:

Stig Cronberg

Simplified monitoring of aminoglycosides
J. Antimicrob. Chemother. 1994 34: 819-827; doi:10.1093/jac/34.5.819 [Abstract] [PDF] [Request Permissions]  

For debate:

Alasdair MacGowan and David Reeves

For debate: Serum aminoglycoside concentrations: the case for routine monitoring
J. Antimicrob. Chemother. 1994 34: 829-837; doi:10.1093/jac/34.5.829 [PDF] [Request Permissions]  

Correspondence:

V. R. LÓPEZ-MARTIN, C. HURTADO, C. PÉREZ-GIRALDO, and A. C. GÓMEZ-GARCIA

In-vitro activity of ciprofloxacin in the presence of non-antibacterial drugs: J. Antimicrobial Chemother 1994; 34: 839-840.
J. Antimicrob. Chemother. 1994 34: 839-847; doi:10.1093/jac/34.5.839 [PDF] [Request Permissions]  

S. E. TEBBS, E. L. VEALE, and T. S. J. ELLIOTT

A comparison of the in-vitro activity of amphotericin B with that of liposomal amphotericin B with that of liposomal amphotericin B against Candida albicans colonising central venous catheters
J. Antimicrob. Chemother. 1994 34: 840-841; doi:10.1093/jac/34.5.840 [PDF] [Request Permissions]  

J. E. CORKILL, A. PERCIVAL, P. McDONALD, and A. I. BAMBER

Detection of quinolone resistance in Haemophilusspp.
J. Antimicrob. Chemother. 1994 34: 841-844; doi:10.1093/jac/34.5.841 [PDF] [Request Permissions]  

T. C. BOSWELL, K. J. NYE, and E. G. SMITH

Penicillin- and Penicillin-cephalosporin-resistant pneumococcal septicaemia
J. Antimicrob. Chemother. 1994 34: 844-845; doi:10.1093/jac/34.5.844 [PDF] [Request Permissions]  

M. LONTIE, J. VERHAEGEN, M.-L. CHASSEUR-LIBOTTE, and L. VERBIST

Salmonella typhimurium serovar copenhagen highly resistent to fluoroquinolones
J. Antimicrob. Chemother. 1994 34: 845-846; doi:10.1093/jac/34.5.845 [PDF] [Request Permissions]  

P. SEETULSINGH and R. E. HOLLIMAN

Entercoccus faecium with high-level resistance to gentamicin and ampicillin: an emerging clinical problem
J. Antimicrob. Chemother. 1994 34: 846-847; doi:10.1093/jac/34.5.846 [PDF] [Request Permissions]  

JOSE M. AGUADO, MANUEL HIDALGO, and JUAN L. RIDRlGUEZ-TUDELA

Successful treatment of candida peritonitis with fluconazole
J. Antimicrob. Chemother. 1994 34: 847; doi:10.1093/jac/34.5.847 [PDF] [Request Permissions]  

Book review:

R. P. ALLAKER

Book review
J. Antimicrob. Chemother. 1994 34: 849; doi:10.1093/jac/34.5.849 [PDF] [Request Permissions]  

Errata:

Erratum
J. Antimicrob. Chemother. 1994 34: 851; doi:10.1093/jac/34.5.851 [Abstract] [PDF] [Request Permissions]  

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