Journal of Antimicrobial Chemotherapy

Leading articles:

PHILIPPA EASTERBROOK and MARTIN J. WOOD

Leading article
J. Antimicrob. Chemother. 1994 34: 307-311; doi:10.1093/jac/34.3.307 [PDF] [Request Permissions]  

Review:

Ying Zhang and Douglas Young

Molecular genetics of drug resistance in Mycobacterium tuberculosis
J. Antimicrob. Chemother. 1994 34: 313-319; doi:10.1093/jac/34.3.313 [Abstract] [PDF] [Request Permissions]  

Original articles:

R. A. Bojar, W. J. Cunliffe, and K. T. Holland

Disruption of the transmembrane pH gradient—a possible mechanism for the antibacterial action of azelaic acid in Propionibucterium acnes and Staphylococcus epidermidis
J. Antimicrob. Chemother. 1994 34: 321-330; doi:10.1093/jac/34.3.321 [Abstract] [PDF] [Request Permissions]  

T. lchimiya, T. Yamasaki, and M. Nasu

In-vitro effects of antimicrobial agents on Pseudomonas aeruginosabiofilm formation
J. Antimicrob. Chemother. 1994 34: 331-341; doi:10.1093/jac/34.3.331 [Abstract] [PDF] [Request Permissions]  

W. W. Yew, L. J. V. Piddock, M. S. K. Li, D. Lyon, C. Y. Chan, and A. F. B. Cheng

In-vitro activity of quinolones and macrolides against mycobacteria
J. Antimicrob. Chemother. 1994 34: 343-351; doi:10.1093/jac/34.3.343 [Abstract] [PDF] [Request Permissions]  

I. N. Simpson, J. Finlay, D. J. Winstanley, N. Dewhurst, J. W. Nelson, S. L. Butler, and J. R. W. Govan

Multi-resistance isolates possessing characteristics of both Burkholderia (Pseudomonas) cepacia and Burkholderia gladioli from patients with cystic fibrosis
J. Antimicrob. Chemother. 1994 34: 353-361; doi:10.1093/jac/34.3.353 [Abstract] [PDF] [Request Permissions]  

Ross J. Davidson, Glen R. Drobot, James A. Karlowsky, George G. Zhanel, Robert Philips, and Daryl J. Hoban

The accumulation of fluoroquinolones in Staphylococcus aureus during the postantibiotic effect
J. Antimicrob. Chemother. 1994 34: 363-370; doi:10.1093/jac/34.3.363 [Abstract] [PDF] [Request Permissions]  

Johanne Blais, Denis Beauchamp, and Suzanne Chamberland

Azithromycin uptake and intracellular accumulation by Toxoplasma gondii-infected macrophages
J. Antimicrob. Chemother. 1994 34: 371-382; doi:10.1093/jac/34.3.371 [Abstract] [PDF] [Request Permissions]  

Masumi Aoki, Yasuo Ono, Otohiko Kunii, and Elliot Goldstein

Effect of newer quinolones on the extra- and intra-cellular chemiluminescence response of human polymorphonuclear leucocytes
J. Antimicrob. Chemother. 1994 34: 383-390; doi:10.1093/jac/34.3.383 [Abstract] [PDF] [Request Permissions]  

Richard N. Greenberg, Paul Cayavee, Linda S. Danko, Karen Bowen, Robert Montazemi, Paul A. Kearney, Steven B. Johnson, and William E. Strodel

Comparison of cefoperazone plus sulbactam with clindamycin plus gentamicin as treatment for intra-abdominal infections
J. Antimicrob. Chemother. 1994 34: 391-401; doi:10.1093/jac/34.3.391 [Abstract] [PDF] [Request Permissions]  

Brief reports:

Roberto C. Arduino, Mira Frosolono, and Barbara E. Murray

In-vitro activity of OPC-17116 against bacterial enteric pathogens
J. Antimicrob. Chemother. 1994 34: 403-407; doi:10.1093/jac/34.3.403 [PDF] [Request Permissions]  

G. Rubinstein, K. Dunkin, and A. J. Howard

The susceptibility of Helicobacter pylori to 12 antimicrobial agents, omeprazole and bismuth salts
J. Antimicrob. Chemother. 1994 34: 409-413; doi:10.1093/jac/34.3.409 [PDF] [Request Permissions]  

F. Namavar, W. P. J. Severin, E. Stobberingh, T. Smeets, and D. M. MacLaren

The sensitivity of clinical isolates of anaerobic species to piperacillin-tazobactam and other antimicrobial agents
J. Antimicrob. Chemother. 1994 34: 415-419; doi:10.1093/jac/34.3.415 [PDF] [Request Permissions]  

Claudio Piersimoni, Stefano Bornigia, Giuseppina De Sio, and Giorgio Scalise

Bacteriostatic and bactericidal activities of paromomycin against Mycobacterium avium complex isolates
J. Antimicrob. Chemother. 1994 34: 421-424; doi:10.1093/jac/34.3.421 [Abstract] [PDF] [Request Permissions]  

C. M. McMullin, L. O. White, A. P. MacGowan, H. A. Holt, A. M. Lovering, and D. S. Reeves

Assay of serum teicoplanin concentrations in clinical specimens: a comparison of isocratic high performance liquid chromatography with polarisation fluoroimmunoassay and bioassay
J. Antimicrob. Chemother. 1994 34: 425-429; doi:10.1093/jac/34.3.425 [PDF] [Request Permissions]  

Antimicrobial Practice:

R. Janknegt, W. J. A. Wijnands, and E. E. Stobberingh

Antibiotic policies in Dutch hospitals for the treatment of pneumonia
J. Antimicrob. Chemother. 1994 34: 431-442; doi:10.1093/jac/34.3.431 [Abstract] [PDF] [Request Permissions]  

Correspondence:

JOSEPH P. IACONIS, HARRIETTE L. NADLER, DONALD H. PITKIN, and WAHEED SHEIKH

Are all carbapenems created equal?
J. Antimicrob. Chemother. 1994 34: 443-444; doi:10.1093/jac/34.3.443 [PDF] [Request Permissions]  

GEORGE N. ROLINSON

A clarithromycin sensitivity survey
J. Antimicrob. Chemother. 1994 34: 444-445; doi:10.1093/jac/34.3.444 [PDF] [Request Permissions]  

J. DURODIE and B. SLOCOMBE

A clarithromycin sensitivity survey
J. Antimicrob. Chemother. 1994 34: 446; doi:10.1093/jac/34.3.446 [PDF] [Request Permissions]  

D. J. LYON, S. W. CHEUNG, C. Y. CHAN, and A. F. B. CHENG

Rapid HPLC assay of clinafloxacin, fleroxacin, levofloxacin, sparfloxacin and tosufloxacin
J. Antimicrob. Chemother. 1994 34: 446-448; doi:10.1093/jac/34.3.446-a [PDF] [Request Permissions]  

B. CORONEL, F. PERSAT, D. DOREZ, J. F. MOSKOVTCHENKO, M. A. PEINS, and A. MERCATELLO

Itraconazole concentrations during continuous haemodiafiltration
J. Antimicrob. Chemother. 1994 34: 448-449; doi:10.1093/jac/34.3.448 [PDF] [Request Permissions]  

A. J. STORM, K. P. BOUTER, R.J.A. DIEPERSLOOT, J. D. BANGA, R. G. BEERENS, and D. W. ERKELENS

Tissue concentrations of an orally administered antibiotic in diabetic patients with foot infections
J. Antimicrob. Chemother. 1994 34: 449-451; doi:10.1093/jac/34.3.449 [PDF] [Request Permissions]  

S. SHAUNAK and J. COHEN

Lack of Toxicity of long-term, high total dose liposomal amphotericin
J. Antimicrob. Chemother. 1994 34: 452; doi:10.1093/jac/34.3.452 [PDF] [Request Permissions]  

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