Journal of Antimicrobial Chemotherapy

Leading articles:

A. KHWAJA and D. C. LINCH

Haemopoietic growth factors in the treatment of infection in non-neutropenic patients
J. Antimicrob. Chemother. 1994 33: 679-683; doi:10.1093/jac/33.4.679 [PDF] [Request Permissions]  

Review:

John M. Domagala

Structure-activity and structure-side-effect relationships for the quinolone antibacterials
J. Antimicrob. Chemother. 1994 33: 685-706; doi:10.1093/jac/33.4.685 [Abstract] [PDF] [Request Permissions]  

Original articles:

Laura C. F. Hibbert-Rogers, John Heritage, Neil Todd, and Peter M. Hawkey

Convergent evolution of TEM-26, a ß-lactamase with extended-spectrum activity
J. Antimicrob. Chemother. 1994 33: 707-720; doi:10.1093/jac/33.4.707 [Abstract] [PDF] [Request Permissions]  

Xu Meng, Charles H. Nightingale, Kevin R. Sweeney, and Richard Quintiliani

Loss of bactericidal activities of quinolones during the post-antibiotic effect induced by rifampicin
J. Antimicrob. Chemother. 1994 33: 721-728; doi:10.1093/jac/33.4.721 [Abstract] [PDF] [Request Permissions]  

B. Heym, O. Lacroix, Y. Péan, J. Gertner, M. H. Nicolas, and V. Jarlier

Use of cefotaxime or ceftazidime susceptibility tests for predicting susceptibility of Enterobacteriaceae and Pseudomonas aeruginosa
J. Antimicrob. Chemother. 1994 33: 729-735; doi:10.1093/jac/33.4.729 [Abstract] [PDF] [Request Permissions]  

J. F. Desnottes and N. Diallo

Effect of sparfloxacin on Staphylococcus aureus adhesiveness and phagocytosis
J. Antimicrob. Chemother. 1994 33: 737-746; doi:10.1093/jac/33.4.737 [Abstract] [PDF] [Request Permissions]  

E. Culebras, J. C. Perez-Diaz, J. Blazquez, R. Alonso, and F. Baquero

In-vitro synergy between aminoglycosides deployed against Staphylococcus spp. harbouring a 6'-aminoglycoside acetyltransferase, 2''-aminoglycoside phosphotransferase enzyme
J. Antimicrob. Chemother. 1994 33: 747-755; doi:10.1093/jac/33.4.747 [Abstract] [PDF] [Request Permissions]  

Cinzia Reda, Teresa Quaresima, and Maddalena Castellani Pastoris

In-vitro activity of six intracellular antibiotics against Legionella pneumophila strains of human and environmental origin
J. Antimicrob. Chemother. 1994 33: 757-764; doi:10.1093/jac/33.4.757 [Abstract] [PDF] [Request Permissions]  

Eisaku Tanaka, Kanthiah Kanthakumar, Diana R. Cundell, Kenneth W. T. Tsang, Graham W. Taylor, Fumiyuki Kuze, Peter J. Cole, and Robert Wilson

The effect of erythromycin on Pseudomonas aeruginosa and neutrophil mediated epithelial damage
J. Antimicrob. Chemother. 1994 33: 765-775; doi:10.1093/jac/33.4.765 [Abstract] [PDF] [Request Permissions]  

Itzhak Brook and G. David Ledney

Quinolone therapy in the prevention of endogenous and exogenous infection after irradiation
J. Antimicrob. Chemother. 1994 33: 777-784; doi:10.1093/jac/33.4.777 [Abstract] [PDF] [Request Permissions]  

G. P. Voorn, J. Thompson, W. H. F. Goessens, W. C. Schmal-Bauer, P. H. M. Broeders, and M. F. Michel

Efficacy of ciprofloxacin in treatment and prophylaxis of experimental Staphylococcus aureus endocarditis caused by a cloxacillin-tolerant strain and its non-tolerant variant
J. Antimicrob. Chemother. 1994 33: 785-794; doi:10.1093/jac/33.4.785 [Abstract] [PDF] [Request Permissions]  

A. Shah, J. Lettieri, L. Kaiser, R. Echols, and A. H. Heller

Comparative pharmacokinetics and safety of ciprofloxacin 400 mg iv thrice daily versus 750 mg po twice daily
J. Antimicrob. Chemother. 1994 33: 795-801; doi:10.1093/jac/33.4.795 [Abstract] [PDF] [Request Permissions]  

C. Lidman, U. Bronner, L. L. Gustafsson, and L. Rombo

Plasma pentamidine concentrations vary between individuals with Pneumocystis carinii pneumonia and the drug is actively secreted by the kidney
J. Antimicrob. Chemother. 1994 33: 803-810; doi:10.1093/jac/33.4.803 [Abstract] [PDF] [Request Permissions]  

Kyle Vance-Bryan, John C. Rotschafer, Susan S. Gilliland, Keith A. Rodvold, Colleen M. Fitzgerald, and David R. P. Guay

A comparative assessment of vancomycin-associated nephrotoxicity in the young versus the elderly hospitalized patient
J. Antimicrob. Chemother. 1994 33: 811-821; doi:10.1093/jac/33.4.811 [Abstract] [PDF] [Request Permissions]  

Jan M. Prins, Harry R. Büller, Ed J. Kuijper, Rinze A. Tange, and Peter Speelman

Once-daily gentamicin versus once-daily netilmicin in patients with serious infections—a randomized clinical trial
J. Antimicrob. Chemother. 1994 33: 823-835; doi:10.1093/jac/33.4.823 [Abstract] [PDF] [Request Permissions]  

D. D'Antonio, R. Piccolomini, A. Iacone, G. Fioritoni, G. Parruti, S. Betti, A. M. Quaglietta, P. Accorsi, M. Dell'Isola, and C. Favalli

Comparison of ciprofloxacin, ofloxacin and pefloxacin for the prevention of the bacterial infection in neutropenic patients with haematological malignancies
J. Antimicrob. Chemother. 1994 33: 837-844; doi:10.1093/jac/33.4.837 [Abstract] [PDF] [Request Permissions]  

Brief reports:

C. Pérez-Giraldo, A. Rodríguez-Benito, F. J. Morán, C. Hurtado, M. T. Blanco, and A. C. Gómez-García

In-vitro slime production by Staphylococcus epidermidis in presence of subinhibitory concentrations of ciprofloxacin, ofloxacin and sparfloxacin
J. Antimicrob. Chemother. 1994 33: 845-848; doi:10.1093/jac/33.4.845 [PDF] [Request Permissions]  

J. M. Andrews and R. Wise

The in-vitro activity of a new semi-synthetic streptogramin compound, RP 59500, against staphylococci and respiratory pathogens
J. Antimicrob. Chemother. 1994 33: 849-853; doi:10.1093/jac/33.4.849 [PDF] [Request Permissions]  

Y. Crenn, M. Meyran, T. Samson, and J. D. Cavallo

Bactericidal activity of six antibiotics against Neisseria gonorrhoeae
J. Antimicrob. Chemother. 1994 33: 855-860; doi:10.1093/jac/33.4.855 [PDF] [Request Permissions]  

Siew-Fah Yeo and David M. Livermore

Comparative in-vitro activity of biapenem and other carbapenems against Haemophilus influenzae isolates with known resistance mechanisms to ampicillin
J. Antimicrob. Chemother. 1994 33: 861-865; doi:10.1093/jac/33.4.861 [PDF] [Request Permissions]  

K. Serdar Diker, Gulsen Hascelik, and Seyda Diker

Development of a technique for detecting antimicrobial susceptibility of unculturable gastric spiral bacterium Gastrospirillum hominis
J. Antimicrob. Chemother. 1994 33: 867-870; doi:10.1093/jac/33.4.867 [PDF] [Request Permissions]  

Eckart Wildling, Lars Jenne, Wolfgang Graninger, Ulrich Bienzle, and Peter G. Kremsner

High dose chloroquine versus micronized halofantrine in chloroquine-resistant Plasmodium falciparum malaria
J. Antimicrob. Chemother. 1994 33: 871-875; doi:10.1093/jac/33.4.871 [PDF] [Request Permissions]  

D. A. F. Lynch, G. M. Sobala, B. Gallacher, M. F. Dixon, and A. T. R. Axon

Effectiveness of a five times daily triple therapy regimen against Heticobacter pylori
J. Antimicrob. Chemother. 1994 33: 877-879; doi:10.1093/jac/33.4.877 [PDF] [Request Permissions]  

Correspondence:

ZIAUDDIN S. HASHMI and JOHN M. B. SMITH

Quinolone resistance in Pseudomonas aeruginosa
J. Antimicrob. Chemother. 1994 33: 881-883; doi:10.1093/jac/33.4.881 [PDF] [Request Permissions]  

D. FELMINGHAM, M. J. ROBBINS, G. GHOSH, and K. COOPER

Disc diffusion susceptibility testing with ceftriaxone
J. Antimicrob. Chemother. 1994 33: 883-884; doi:10.1093/jac/33.4.883 [PDF] [Request Permissions]  

DAVID J. WAGHORN and SADHANA YELAMANCHILI

Macrolide representation for disc diffusion sensitivity testing against Haemophilus influenzae
J. Antimicrob. Chemother. 1994 33: 884-885; doi:10.1093/jac/33.4.884 [PDF] [Request Permissions]  

S. BONACORSI and E BINGEN

Bactericidal activity of erythromycin associated with sulphisoxazole against theinfectious agents most frequently responsible for acute infantile otitis media
J. Antimicrob. Chemother. 1994 33: 885-886; doi:10.1093/jac/33.4.885 [PDF] [Request Permissions]  

P. HEISIC, L. TZOUVELEKIS, A. VATOPOULOS, and N. LEGAKIS

Ciprofloxacin resistance in enterobacterial clinical isolates
J. Antimicrob. Chemother. 1994 33: 887-888; doi:10.1093/jac/33.4.887 [PDF] [Request Permissions]  

P. C. GOKHALE, N. A. KSHIRSAGAR, M. U. KHAN, S. K. PANDYA, R. H. MERCHANT, K. P. MEHTA, and M. P. COLACO

Treatment of candiduria with liposomal ampbotericin B (L-AmpB-LRC) in children
J. Antimicrob. Chemother. 1994 33: 889-891; doi:10.1093/jac/33.4.889 [PDF] [Request Permissions]  

BRIAN L. JONES, HUGO A. LUDLAM, and DEREK F. J. BROWN

High dose ampicillin for the treatment of high-level aminoglycoside resistant enterococcal endocarditis
J. Antimicrob. Chemother. 1994 33: 891-892; doi:10.1093/jac/33.4.891 [PDF] [Request Permissions]  

Book review:

I. PHILLIPS

Book review
J. Antimicrob. Chemother. 1994 33: 893; doi:10.1093/jac/33.4.893 [PDF] [Request Permissions]  

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