Journal of Antimicrobial Chemotherapy

Leading articles:

J.J.S. SNELL

Problems in susceptibility testings—findings of UK NEQAS for microbiology
J. Antimicrob. Chemother. 1994 33: 1-4; doi:10.1093/jac/33.1.1 [PDF] [Request Permissions]  

R. C. READ and R. G. FINCH

Prophylaxis after splenectomy: J Antimicrob Chemother 1994; 33: 4–6
J. Antimicrob. Chemother. 1994 33: 4-6; doi:10.1093/jac/33.1.4 [PDF] [Request Permissions]  

Review:

Herminia de Lencastre, Boudewijn L. M. de Jonge, Peter R. Matthews, and Alexander Tomasz

Molecular aspects of methicillin resistance in Staphylococcus aureus
J. Antimicrob. Chemother. 1994 33: 7-24; doi:10.1093/jac/33.1.7 [PDF] [Request Permissions]  

Original articles:

K. J. Towner, A. Brennan, Y. Zhang, C. A. Holtham, J. L. Brough, and G. I. Carter

Genetic structures associated with spread of the type la trimethoprimresistant dihydrofolate reductase gene amongst Escherichia coli strains isolated in the Nottingham area of the United Kingdom
J. Antimicrob. Chemother. 1994 33: 25-32; doi:10.1093/jac/33.1.25 [Abstract] [PDF] [Request Permissions]  

P. C. Appelbaum, S. K. Spangler, G. A. Pankuch, A. Philippon, M. R. Jacobs, R. Shiman, E. J. C. Goldstein, and D. M. Citron

Characterization of a ß-lactamase from Clostridium clostridioforme
J. Antimicrob. Chemother. 1994 33: 33-40; doi:10.1093/jac/33.1.33 [Abstract] [PDF] [Request Permissions]  

Keith T. Holland, David Taylor, and Angela M. Farrell

The effect of glycerol monolaurate on growth of, and production of Toxic Shock Syndrome Toxin-1 and lipase by, Staphylococcus aureus
J. Antimicrob. Chemother. 1994 33: 41-55; doi:10.1093/jac/33.1.41 [Abstract] [PDF] [Request Permissions]  

F. J. Morán, L. F. Puente, C. Pérez-Giraldo, C. Hurtado, M. T. Blanco, and A. C. Gómez-Garcia

Effects of cefpirome in comparison with cefuroxime against human polymorphonuclear leucocytes in vitro
J. Antimicrob. Chemother. 1994 33: 57-62; doi:10.1093/jac/33.1.57 [Abstract] [PDF] [Request Permissions]  

Itzhak Brook and G. David Ledney

Effect of antimicrobial therapy on the gastrointestinal bacterial flora, infection and mortality in mice exposed to different doses of irradiation
J. Antimicrob. Chemother. 1994 33: 63-72; doi:10.1093/jac/33.1.63 [Abstract] [PDF] [Request Permissions]  

John R. Perfect and Kathleen A. Wright

Amphotericin B lipid complex in the treatment of experimental cryptococcal meningitis and disseminated candidosis
J. Antimicrob. Chemother. 1994 33: 73-81; doi:10.1093/jac/33.1.73 [Abstract] [PDF] [Request Permissions]  

Naoki Ikeda, Shuichi Kaneko, Atsushi Shimoda, Yutaka Inagaki, Masashi Unoura, Mineaki Okada, Yoshiaki Yonekawa, Katsutoshi Takahashi, and Kenichi Kobayashi

Efficiency of oxetanocin-G, a novel nucleoside against the woodchuck hepatitis virus
J. Antimicrob. Chemother. 1994 33: 83-89; doi:10.1093/jac/33.1.83 [Abstract] [PDF] [Request Permissions]  

L. Aguilar, C. Esteban, J. Frias, I. Pérez-Balcabao, A. J. Carcas, and R. Dal-Ré

Cefminox: correlation between in-vitro susceptibility and pharmacokinetics and serum bactericidal activity in healthy volunteers
J. Antimicrob. Chemother. 1994 33: 91-101; doi:10.1093/jac/33.1.91 [Abstract] [PDF] [Request Permissions]  

C. Catchpole, J. M. Andrews, J. Woodcock, and R. Wise

The comparative pharmacokinetics and tissue penetration of single-dose ciprofloxacin 400 mg iv and 750 mg po
J. Antimicrob. Chemother. 1994 33: 103-110; doi:10.1093/jac/33.1.103 [Abstract] [PDF] [Request Permissions]  

Roger Echols, Melvin P. Weinstein, Brian O'Keeffe, Anita Shah, and Allen H. Heller

Comparative crossover assessment of serum bactericidal activity and pharmacokinetics of ciprofloxacin and ofloxacin
J. Antimicrob. Chemother. 1994 33: 111-118; doi:10.1093/jac/33.1.111 [Abstract] [PDF] [Request Permissions]  

M. A. Pue, S. K. Pratt, A. J. Fairless, S. Fowles, J. Laroche, P. Georgiou, and W. Prince

Linear pharmacokinetics of penciclovir following administration of single oral doses of famciclovir 125, 250, 500 and 750 mg to healthy volunteers
J. Antimicrob. Chemother. 1994 33: 119-127; doi:10.1093/jac/33.1.119 [Abstract] [PDF] [Request Permissions]  

S. L. Hill, D. Bilton, M. M. Johnson, A. Pye, J. L. Mitchell, and R. A. Stockley

Sputum and serum pharmacokinetics of loracarbef (LY163892) in patients with chronic bronchial sepsis
J. Antimicrob. Chemother. 1994 33: 129-136; doi:10.1093/jac/33.1.129 [Abstract] [PDF] [Request Permissions]  

Brief reports:

Ronald N. Jones, Mary S. Barrett, and Meridith E. Erwin

In-vitro activity of FK-037, a new parenteral cephalosporin
J. Antimicrob. Chemother. 1994 33: 137-144; doi:10.1093/jac/33.1.137 [PDF] [Request Permissions]  

M. D. Smith, V. Wuthiekanuna, A. L. Walsh, and N. J. White

Susceptibility of Pseudomonas pseudomallei to some newer ß-lactam antibiotics and antibiotic combinations using time-kill studies
J. Antimicrob. Chemother. 1994 33: 145-149; doi:10.1093/jac/33.1.145 [PDF] [Request Permissions]  

Jean-Claude Chapalain, Jean-Yves Dusseau, Jean-David Perrier-Gros-Claude, Yvan Rouby, and Mathieu Bartoli

Effect of rifampicin chemoprophylaxis on the aerobic bacterial flora of the oropharynx
J. Antimicrob. Chemother. 1994 33: 151-155; doi:10.1093/jac/33.1.151 [PDF] [Request Permissions]  

J. M. Woodcock, M. R. Wolstenholme, J. M. Andrews, and R. Wise

Determination of 6-ß-bromopenicillanic acid (brobactam) in human serum by high-performance liquid chromatography (HPLC) using solid phase extraction for sample preparation
J. Antimicrob. Chemother. 1994 33: 157-161; doi:10.1093/jac/33.1.157 [PDF] [Request Permissions]  

N. Rolando, J. J. Wade, J. N. Philpott-Howard, M. W. Casewell, and R. Williams

The penetration of imipenem/cilastatin into ascitic fluid in patients with chronic liver disease
J. Antimicrob. Chemother. 1994 33: 163-167; doi:10.1093/jac/33.1.163 [PDF] [Request Permissions]  

Antimicrobial practice:

R. Janknegt and J. W. M. van der Meer

Sequential therapy with intravenous and oral cephalosporins
J. Antimicrob. Chemother. 1994 33: 169-177; doi:10.1093/jac/33.1.169 [Abstract] [PDF] [Request Permissions]  

Correspondence:

J. R. FRANKLIN and J. A. HOBSON

P-nitrophenylglycerol in susceptibility media alters the MICs of antimicrobial agents for Pseudomonas aeruginosa: J Antimicrob Chemother 1994, 33: 179
J. Antimicrob. Chemother. 1994 33: 179; doi:10.1093/jac/33.1.179 [PDF] [Request Permissions]  

F. J. BONE, R. MUNDLE, B. A. S. DALE, K. S. MACRAE, and W. WALLACE

P-nitrophenyglycerol in susceptility media alters the MICs of a antimicrobial agents for Psedomonas aeruginosa
J. Antimicrob. Chemother. 1994 33: 179-180; doi:10.1093/jac/33.1.179-a [PDF] [Request Permissions]  

PETER B. WARD

P-nitrophenyglycerol in susceptility media alters the MICs of a antimicrobial agents for Psedomonas aeruginosa
J. Antimicrob. Chemother. 1994 33: 180-181; doi:10.1093/jac/33.1.180 [PDF] [Request Permissions]  

EDOUARD BINGEN

Rapid killing of bacteria and inhibition of endotoxin activity
J. Antimicrob. Chemother. 1994 33: 181; doi:10.1093/jac/33.1.181 [PDF] [Request Permissions]  

G. BONFIGLIO and D. M. LIVERMORE

Zine ions and medium-dependent susceptibility to ß-lactams in Xanthomona maltophilia
J. Antimicrob. Chemother. 1994 33: 181-182; doi:10.1093/jac/33.1.181-a [PDF] [Request Permissions]  

J. I. ALÓS

Problems associated with susceptibility testing of co-amoxiclav: an interpretive solution
J. Antimicrob. Chemother. 1994 33: 183; doi:10.1093/jac/33.1.183 [PDF] [Request Permissions]  

J. A. GARCÍA-RODRÍGUEZ, J. E. GARCÍA-SÁNCHEZ, I. TRUJILLANO-MARTÍN, E. GARCÍA-SÁNCHEZ, I. GARCÍA-GARCÍA, and J. FRESNADILLO-MARTINEZ

L-627, a novel carbapenem: in-vitro activity against anaerobes
J. Antimicrob. Chemother. 1994 33: 183-186; doi:10.1093/jac/33.1.183-a [PDF] [Request Permissions]  

CRISTINA LATORRE, CARMEN MUÑOZ, GLÒRIA TRUJILLO, TERESA JUNCOSA, and PEDRO CLARÓS

Susceptibility of pneumococci isolated from middle ear effusions to antimicrobial agents commonly used in otitis media
J. Antimicrob. Chemother. 1994 33: 186-187; doi:10.1093/jac/33.1.186 [PDF] [Request Permissions]  

I. M. GOULD, K. J. FORBES, and G. S. GORDON

Quinolone resistant Haemophilus influenzae
J. Antimicrob. Chemother. 1994 33: 187-188; doi:10.1093/jac/33.1.187 [PDF] [Request Permissions]  

ANA JIMÉNEZ, JORGE B. VELÁZQUEZ, JOAQUIN RODRÍGUEZ, ALMUDENA TINAJAS, and TOMÁS G. VILLA

Prevalence of fluoroquinolone resistance in clinical strains of Campylobacter jejuni isolated in Spain
J. Antimicrob. Chemother. 1994 33: 188-190; doi:10.1093/jac/33.1.188 [PDF] [Request Permissions]  

SAMIR K. SAHA and SOUMITRA K. SAHA

Antibiotic resistance of Salmonella typhi in Bangladesh
J. Antimicrob. Chemother. 1994 33: 190-191; doi:10.1093/jac/33.1.190 [PDF] [Request Permissions]  

D. L. SMITH, D. E. STABLEFORTH, and A. M. GEDDES

Evaluation of a once-daily netilmicin regimen in the treatment of cystic fibrosis
J. Antimicrob. Chemother. 1994 33: 191-193; doi:10.1093/jac/33.1.191 [PDF] [Request Permissions]  

O. M. VAN DELDEN, D. J. VAN LEEUWEN, P. L. M. JANSEN, F. J. HOEK, K. HUIBREGTSE, and G. N. J. TYTGAT

Biliary excretion of ceftriaxone into non-stagnant and stagnant bile
J. Antimicrob. Chemother. 1994 33: 193-194; doi:10.1093/jac/33.1.193 [PDF] [Request Permissions]  

Book review:

R. C. B. SLACK

Book review
J. Antimicrob. Chemother. 1994 33: 195; doi:10.1093/jac/33.1.195 [PDF] [Request Permissions]  

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