Journal of Antimicrobial Chemotherapy

Leading articles:

R. J. HAY

The prevention of invasive aspergillosis-a realistic goal?
J. Antimicrob. Chemother. 1993 32: 515-517; doi:10.1093/jac/32.4.515 [PDF] [Request Permissions]  

Review:

F. M. MacKenzie and I. M. Gould

The post-antibiotic effect
J. Antimicrob. Chemother. 1993 32: 519-537; doi:10.1093/jac/32.4.519 [Abstract] [PDF] [Request Permissions]  

Original articles:

Valerie S. Bernan, Deborah M. Roll, Chris M. Ireland, Michael Greenstein, William M. Maiese, and Deborah A. Steinberg

A study on the mechanism of action of sceptrin, an antimicrobial agent isolated from the South Pacific sponge Agelas mauritiana
J. Antimicrob. Chemother. 1993 32: 539-550; doi:10.1093/jac/32.4.539 [Abstract] [PDF] [Request Permissions]  

F. Huygens

Vancomycin binding to cell walls of non-streptococcal vancomycin resistant bacteria
J. Antimicrob. Chemother. 1993 32: 551-558; doi:10.1093/jac/32.4.551 [Abstract] [PDF] [Request Permissions]  

Kirsti Jalakas Pörnull, Evelyn Göransson, Ann-Sofie Rytting, and Kathrine Dornbusch

Extended-spectrum ß-Iactamases in Escherichia coli and Klebsiella spp. in European septicaemia isolates
J. Antimicrob. Chemother. 1993 32: 559-570; doi:10.1093/jac/32.4.559 [Abstract] [PDF] [Request Permissions]  

Candace J. Krepel, Claudia M. Gohr, Charles E. Edmiston, and Robert E. Condon

Microbroth versus agar dilution for susceptibility testing of fluoroquinolones and other agents against anaerobic bacteria
J. Antimicrob. Chemother. 1993 32: 571-575; doi:10.1093/jac/32.4.571 [Abstract] [PDF] [Request Permissions]  

Matthew E. Levison, Peter G. Pitsakis, Phyllis L. May, and Caroline C. Johnson

The bactericidal activity of magainins against Pseudomonas aeruginosa and Enterococcus faecium
J. Antimicrob. Chemother. 1993 32: 577-585; doi:10.1093/jac/32.4.577 [Abstract] [PDF] [Request Permissions]  

Max Maurin and Didier Raoult

Antimicrobial susceptibility of Rochalimaea quintana, Rocholimaea vinsonii, and the newly recognized Rochalimaea henselae
J. Antimicrob. Chemother. 1993 32: 587-594; doi:10.1093/jac/32.4.587 [Abstract] [PDF] [Request Permissions]  

F. W. Goldstein, Y. Péan, A. Rosato, J. Gertner, L. Gutmann, and The Vigll'Roc Study Group

Characterization of ceftriaxone-resistant Enterobacteriaceae: a multicentre study in 26 French hospitals
J. Antimicrob. Chemother. 1993 32: 595-603; doi:10.1093/jac/32.4.595 [Abstract] [PDF] [Request Permissions]  

T. Alarcón, J. Pita, M. López-Brea, and L. J. V. Piddock

High-level quinolone resistance amongst clinical isolates of Escherichia coli and Klebsiella pneumoniae from Spain
J. Antimicrob. Chemother. 1993 32: 605-609; doi:10.1093/jac/32.4.605 [Abstract] [PDF] [Request Permissions]  

J. F. Cade, J. Presneill, V. Sinickas, and A. Hellyar

The optimal dosage of ceftazidime for severe lower respiratory tract infections
J. Antimicrob. Chemother. 1993 32: 611-622; doi:10.1093/jac/32.4.611 [Abstract] [PDF] [Request Permissions]  

Brief reports:

Rajashri G. Deshpande, Mahfuz B. Khan, Deepashree A. Bhat, and Ram G. Navalkar

Inhibition of Mycobacterium avium complex isolates from AIDS patients by garlic (Allium sativum)
J. Antimicrob. Chemother. 1993 32: 623-626; doi:10.1093/jac/32.4.623 [PDF] [Request Permissions]  

Tibor Schmidt, Jeff Froula, and Martin G. Täuber

Clarithromycin lacks bactericidal activity in cerebrospinal fluid in experimental pneumococcal meningitis
J. Antimicrob. Chemother. 1993 32: 627-632; doi:10.1093/jac/32.4.627 [PDF] [Request Permissions]  

Antimicrobial practice:

B. L. Reder, S. L. Nielsen, P. Magnussen, A. Engquist, and N. Frimodt-Møller

Antibiotic usage in an intensive care unit in a Danish university hospital
J. Antimicrob. Chemother. 1993 32: 633-642; doi:10.1093/jac/32.4.633 [PDF] [Request Permissions]  

For debate:

John Urquhart

Variable patient compliance in ambulatory trials—nuisance, threat, opportunity
J. Antimicrob. Chemother. 1993 32: 643-649; doi:10.1093/jac/32.4.643 [PDF] [Request Permissions]  

Correspondence:

H. Y. CHEN and D. M. LIVERMORE

Effects of ß-lactamase induciblilty and derepression on the activity of cefepime and cefpirome against Gram-negative bacteria
J. Antimicrob. Chemother. 1993 32: 651-652; doi:10.1093/jac/32.4.651 [PDF] [Request Permissions]  

MERIDITH E. ERWIN and RONALD N. JONES

Roxithromycin in-vitro susceptibility testing of Haemophilus influenzae by NCCLS methods
J. Antimicrob. Chemother. 1993 32: 652-654; doi:10.1093/jac/32.4.652 [PDF] [Request Permissions]  

MARTHA L. SANCHEZ, RONALD N. JONES, and The United States Consortium for Antimicrobial and Surveillance Trials

Antimicrobial activity of FK-037 against class I ß-lactamase producing species resistant to ceftazidime: a multi-laboratory clinical isolate sample
J. Antimicrob. Chemother. 1993 32: 654-656; doi:10.1093/jac/32.4.654 [PDF] [Request Permissions]  

EMI OSAKI, SAEKO ANJO, YOSHIO ISHIBASHI, and TOSHIHIKO ARAI

Cefodizime enhances formyl-methionyl-leucyl-phenylalanine-induced hydrogen peroxide-production from human neutrophils
J. Antimicrob. Chemother. 1993 32: 656-657; doi:10.1093/jac/32.4.656 [PDF] [Request Permissions]  

MIGUEL LOPEZ DUPLA, ANTONIO GIL AGUADO, PAZ LA VILLA URIOL, VICENTE PINTADO GARCIA, EULALIA VALENCIA ORTEGA, PEDRO MARTINEZ MARTINEZ, and JUAN GARCIA-PUIG

Efficacy of liposomal amphotericin B in the treatment and secondary prophylaxis of visceral leishimaniasis in HIV infected patients: report of two cases
J. Antimicrob. Chemother. 1993 32: 657-659; doi:10.1093/jac/32.4.657 [PDF] [Request Permissions]  

Book review:

SHAHEEN MEHTAR

Book review
J. Antimicrob. Chemother. 1993 32: 661; doi:10.1093/jac/32.4.661 [PDF] [Request Permissions]  

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