Journal of Antimicrobial Chemotherapy

Leading articles:

IAN CHOPRA

Effiux-based antibiotic resistance mechanisms: the evidence for increasing prevalence
J. Antimicrob. Chemother. 1992 30: 737-738; doi:10.1093/jac/30.6.737 [PDF] [Request Permissions]  

P. RICHARD and L. GUTMANN

Sparfloxacin and other new fluoroquinolones
J. Antimicrob. Chemother. 1992 30: 739-742; doi:10.1093/jac/30.6.739 [PDF] [Request Permissions]  

Review:

Helen Glamarellou

Malignant otitis externa: the therapeutic evolution of a lethal infection
J. Antimicrob. Chemother. 1992 30: 745-751; doi:10.1093/jac/30.6.745 [Abstract] [PDF] [Request Permissions]  

Original articles:

M. D. O'Hare and P. E. Reynolds

Novel membrane proteins present in teicoplanin-resistant, vancomycin sensitive, coagulase-negative Staphylococcus spp
J. Antimicrob. Chemother. 1992 30: 753-768; doi:10.1093/jac/30.6.753 [Abstract] [PDF] [Request Permissions]  

Dominique Decré, Guillamue Arlet, Claude Danglot, Jean-Christophe Lucet, Geneviéve Fournier, Engénie Bergogne-Bérézin, and Alain Philippon

A -ß-lactamase-overproducing strain of Alcaligenes denitrificans subsp. xylosoxydans isolated from a case of meningitis
J. Antimicrob. Chemother. 1992 30: 769-779; doi:10.1093/jac/30.6.769 [Abstract] [PDF] [Request Permissions]  

John O. Capobianco, Colette C. Doran, Robert C. Goldman, and Biswanath De

A non-azole inhibitor of lanosterol l4-methy1 demethylase in Candida albicans
J. Antimicrob. Chemother. 1992 30: 781-790; doi:10.1093/jac/30.6.781 [Abstract] [PDF] [Request Permissions]  

I. G. Duguid, E. Evans, M. R. W. Brown, and P. Gilbert

Growth-rate-independent killing by ciprofloxacin of biofilm-derived Staphylococcus epidermidis evidence for cell-cycle dependency
J. Antimicrob. Chemother. 1992 30: 791-802; doi:10.1093/jac/30.6.791 [Abstract] [PDF] [Request Permissions]  

Ian G. Duguid, Elwyn Evans, Michael R. W. Brown, and Peter Gilbert

Effect of biofilm culture upon the susceptibility of Staphylococcus epidermidis to tobramycin
J. Antimicrob. Chemother. 1992 30: 803-810; doi:10.1093/jac/30.6.803 [Abstract] [PDF] [Request Permissions]  

Sharon C. A. Chen, Thomas Gottlieb, Jennifer M. Palmer, Garbrielle Morris, and Gwendolyn L. Gilbert

Antimicrobial susceptibility of anaerobic bacteria in Australia
J. Antimicrob. Chemother. 1992 30: 811-820; doi:10.1093/jac/30.6.811 [Abstract] [PDF] [Request Permissions]  

Sandra J. Wadsworth, Ki-Ho Kim, Vilas Satishchandran, Peter Axelrod, Allan L. Truant, and Byungse Suh

Development of new antibiotic resistance in methicillin-resistant but not methicillin-susceptible Staphylococcus aureus
J. Antimicrob. Chemother. 1992 30: 821-826; doi:10.1093/jac/30.6.821 [Abstract] [PDF] [Request Permissions]  

S. L. Croft, J Hogg, W. E. Gutteridge, A. T. Hudson, and A. W. Randall

The activity of hydroxynaphthoquinones against Leishmania donovani
J. Antimicrob. Chemother. 1992 30: 827-832; doi:10.1093/jac/30.6.827 [Abstract] [PDF] [Request Permissions]  

Pattisapu R. J. Gangadharam and Kishori Parikh

In-vivo activity of streptomycin and clofazimine against established infections of Mycobacterium avium complex in beige mice
J. Antimicrob. Chemother. 1992 30: 833-838; doi:10.1093/jac/30.6.833 [Abstract] [PDF] [Request Permissions]  

David M. Teale and Annie M. Atkinson

Inhibition of nitric oxide synthesis improves survival in a murine peritonitis model of sepsis that is not cured by antibiotics alone
J. Antimicrob. Chemother. 1992 30: 839-842; doi:10.1093/jac/30.6.839 [Abstract] [PDF] [Request Permissions]  

M. J. Leyland, K. F. Bayston, J. Cohen, R. Warren, A. C. Newland, A. J. Bint, C. Cefai, D. G. White, S. A. Murray, D. Bareford, and N. B. Deaney

A comparative study of imipenem versus piperacillin plus gentamicin in the initial management of febrile neutropenic patients with haematological malignancies
J. Antimicrob. Chemother. 1992 30: 843-854; doi:10.1093/jac/30.6.843 [Abstract] [PDF] [Request Permissions]  

Antimicrobial practice:

Peter Devey, Bill Lynch, Mo Malek, Derek Byrne, and Peter Thomas

Cost-effectiveness of single dose cefotaxime plus metronidazole compared with three doses each of cefuroxime plus metronidazole for the prevention of wound infection after colorectal surgery
J. Antimicrob. Chemother. 1992 30: 855-864; doi:10.1093/jac/30.6.855 [Abstract] [PDF] [Request Permissions]  

Correspondence:

J. A. SACRISTAN and J. SOTO

Vancomycin peak concentration and ototoxicity prevention
J. Antimicrob. Chemother. 1992 30: 865; doi:10.1093/jac/30.6.865 [PDF] [Request Permissions]  

R. A. ELSTON and V. SUMMERS

A comparison of the coats of ceftazidime therapy and gentamicin combinations
J. Antimicrob. Chemother. 1992 30: 866-867; doi:10.1093/jac/30.6.866 [PDF] [Request Permissions]  

PETER DAVEY and MO MALEK

Reply
J. Antimicrob. Chemother. 1992 30: 867-868; doi:10.1093/jac/30.6.867 [PDF] [Request Permissions]  

PEI JUN WU, KELVIN SHANNON, and IAN PHILLIPS

ß-Lactamases and susceptibility to ß-lactam antibiotics in Escherickia coil
J. Antimicrob. Chemother. 1992 30: 868-870; doi:10.1093/jac/30.6.868 [PDF] [Request Permissions]  

Y. KOBAYASHI, H. UCHIDA, and Y. KAWAKAMI

Synergy with aztreonam and arbekacin or tobramycin against Pseudomonas aeruginosa from blood
J. Antimicrob. Chemother. 1992 30: 871-872; doi:10.1093/jac/30.6.871 [PDF] [Request Permissions]  

A. BOISIVION, Y. PEAN, J. BEJOT, L. BERARDI-GRASSIAS, A. EME, J. GERTNER, B. HACQUARD, J. MORICE, and M. ROUCHON

ß-Lactam and aminoglycoside resistance among Enterobacteriaceae
J. Antimicrob. Chemother. 1992 30: 872-874; doi:10.1093/jac/30.6.872 [PDF] [Request Permissions]  

A. BOSSERAY, P. LECLERCQ, J. P. STAHL, and M. MICOUD

Penetration of ciprofloxacin into synovial fluid after oral dosing
J. Antimicrob. Chemother. 1992 30: 874-875; doi:10.1093/jac/30.6.874 [PDF] [Request Permissions]  

LEONARDA CORVALA, SHU C. LI, LISA L. IOANNIDES-DEMOS, GLENN BOWES, W. JOHN SPICER, DENIS W. SPELMAN, NICHOLOS TONG, and ALLAN J. McLEAN

A prospective study of the effects of oral probenecid on the pharmacokinetics of intravenous ticarillin in patients with cystic fibrosics
J. Antimicrob. Chemother. 1992 30: 875-878; doi:10.1093/jac/30.6.875 [PDF] [Request Permissions]  

Errata:

Erratum
J. Antimicrob. Chemother. 1992 30: 879; doi:10.1093/jac/30.6.879 [Abstract] [PDF] [Request Permissions]  

Index:

Index
J. Antimicrob. Chemother. 1992 30: 881-890; doi:10.1093/jac/30.6.881 [PDF] [Request Permissions]  

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