Journal of Antimicrobial Chemotherapy

Leading articles:

M. J. G. Farthing

Giardia comes of age: progress in epidemiology, immunology and chemotherapy
J. Antimicrob. Chemother. 1992 30: 563-666; doi:10.1093/jac/30.5.563 [PDF] [Request Permissions]  

FRANCISCO SORIANO

Optimal dosage of ß-lactam antibiotics: time above the MIC and inoculum effect
J. Antimicrob. Chemother. 1992 30: 567-569; doi:10.1093/jac/30.5.567 [Abstract] [PDF] [Request Permissions]  

Review:

N. J. White

Antimalarial drug resistance: the pace quickens
J. Antimicrob. Chemother. 1992 30: 571-585; doi:10.1093/jac/30.5.571 [Abstract] [PDF] [Request Permissions]  

Original articles:

T. H. Farmer, J. Gilbart, and S. W. Elson

Biochemical basis of mupirocin resistance in strains of Staphylococcus aureus
J. Antimicrob. Chemother. 1992 30: 587-596; doi:10.1093/jac/30.5.587 [Abstract] [PDF] [Request Permissions]  

Ashir Kumar, Marshall B. Hay, George A. Maier, and John W. Dyke

Post-antibiotic effect of ceftazidime, ciprofloxacin, imipenem, piperacillin and tobramycin for Pseudomonas cepacia
J. Antimicrob. Chemother. 1992 30: 597-602; doi:10.1093/jac/30.5.597 [Abstract] [PDF] [Request Permissions]  

D. Law, G. M. Megson, Maeve G. L. Keaney, and Leela A. Ganguli

The influence of salt concentration on the detection of methicillin resistance in coagulase-negative staphylococci
J. Antimicrob. Chemother. 1992 30: 603-614; doi:10.1093/jac/30.5.603 [Abstract] [PDF] [Request Permissions]  

Zoe A. Machan, Graham W. Taylor, Tyrone L. Pitt, Peter J. Cole, and Robert Wilson

2-Heptyl-4-hydroxyquinoline N-oxide, an antistaphylococcal agent produced by Pseudomonas aeruginosa
J. Antimicrob. Chemother. 1992 30: 615-623; doi:10.1093/jac/30.5.615 [Abstract] [PDF] [Request Permissions]  

C. S. Lewin, I. Morrissey, and J. T. Smith

The bactericidal activity of sparfloxacin
J. Antimicrob. Chemother. 1992 30: 625-632; doi:10.1093/jac/30.5.625 [Abstract] [PDF] [Request Permissions]  

Nao-aki Watanabe, Ryoichi Hiruma, and Kanemasa Katsu

Comparative in-vitro activities of newer cephalosporins cefclidin, cefepime, and cefpirome against ceftazidime- or imipenem-resistant Pseudomonas aeruginosa
J. Antimicrob. Chemother. 1992 30: 633-641; doi:10.1093/jac/30.5.633 [Abstract] [PDF] [Request Permissions]  

R. J. Kent, M. Bakhtiar, and D. C. Shanson

The in-vitro bactericidal activities of combinations of antimicrobial agents against clinical isolates of Mycobacterium avium-intracellulare
J. Antimicrob. Chemother. 1992 30: 643-650; doi:10.1093/jac/30.5.643 [Abstract] [PDF] [Request Permissions]  

G. J. van Asselt, J. S. Vliegenthart, P. L. C. Petit, J. A. M. van de Klundert, and R. P. Mouton

High-level aminoglycoside resistance among enterococci and group A streptococci
J. Antimicrob. Chemother. 1992 30: 651-659; doi:10.1093/jac/30.5.651 [Abstract] [PDF] [Request Permissions]  

Kevin Shannon, Anna King, and Ian Phillips

Prevalence of resistance to ß-lactam antibiotics in Escherichia coli isolated from blood from 1969–1991
J. Antimicrob. Chemother. 1992 30: 661-672; doi:10.1093/jac/30.5.661 [Abstract] [PDF] [Request Permissions]  

K. Naroa, Y. Iwamoto, K. Tanaka, T. Yamaguchi, and Y. Sekine

Effects of fenbufen on teh pharmacokinetics of sparfloxacinin rats
J. Antimicrob. Chemother. 1992 30: 673-683; doi:10.1093/jac/30.5.673 [Abstract] [PDF] [Request Permissions]  

E. J. Vollaard, H. A. L. Clasener, and A. J. H. M. Janssen

Co-trimoxazole impairs colonization resistance in healthy volunteers
J. Antimicrob. Chemother. 1992 30: 685-691; doi:10.1093/jac/30.5.685 [Abstract] [PDF] [Request Permissions]  

Johan Wiström, Layne O. Gentry, Ann-Chatrin Palmgren, Margaret Price, Carl Erik Nord, Åsa Ljungh, and S. Ragnar Norrby

Ecological effects of short-term ciprofloxacin treatment of travellers' diarrhoea
J. Antimicrob. Chemother. 1992 30: 693-706; doi:10.1093/jac/30.5.693 [Abstract] [PDF] [Request Permissions]  

Ahmad K. Uwaydah, Housam Al Soub, and Issa Matar

Randomized prospective study comparing two dosage regimens of ciprofloxacin for the treatment of typhoid fever
J. Antimicrob. Chemother. 1992 30: 707-711; doi:10.1093/jac/30.5.707 [Abstract] [PDF] [Request Permissions]  

For debate:

J. Peter Donnelly

Describing and comparing in-vitro antimicrobial activity by the box-plot technique
J. Antimicrob. Chemother. 1992 30: 713-719; doi:10.1093/jac/30.5.713 [PDF] [Request Permissions]  

Correspondence:

A. C. SCOTT

Bioassay for glycopeptides
J. Antimicrob. Chemother. 1992 30: 721; doi:10.1093/jac/30.5.721 [PDF] [Request Permissions]  

J. DURODIE and K. COLEMAN

Reply
J. Antimicrob. Chemother. 1992 30: 721; doi:10.1093/jac/30.5.721-a [PDF] [Request Permissions]  

C. GODARD, J. LEROY, and Y. MICHEL-BRIAND

Characterization of imipenem-resistant Pseudomonas aeruginosa strains from cystic fibrosis patients
J. Antimicrob. Chemother. 1992 30: 721-724; doi:10.1093/jac/30.5.721-b [PDF] [Request Permissions]  

INGE C. GYSSENS, PIETER J. VAN DEN BROEK, BART-JAN KULLBERG, YECHIEL A. HEKSTER, and JOS W. M. VAN DER MEER

Optimizing antimicrobial therapy. A method for antimicrobial drug me evaluation
J. Antimicrob. Chemother. 1992 30: 724-727; doi:10.1093/jac/30.5.724 [PDF] [Request Permissions]  

C. FLOREZ, M. J. PEREZ, R. ARETIO, P. PARRAS, and E. MARTIN

Susceptibility of Streptococcus pneumoniae to five antibiotics
J. Antimicrob. Chemother. 1992 30: 727-728; doi:10.1093/jac/30.5.727 [PDF] [Request Permissions]  

F. de' CLARI, T. MENGHINI, G. BIAGGI, and P. MAGNOLI

Septicaemia due to a new species of Rhodococcus that contaminated closed system packed red blood cells—cure with imipenem monotherapy
J. Antimicrob. Chemother. 1992 30: 729-730; doi:10.1093/jac/30.5.729 [PDF] [Request Permissions]  

N. SOMOLINOS, R. ARRANZ, M. C. DEL REY, and M. L. JIMÉNEZ

Superinfections by Escherichia coli resistant to fluoroquinolones in immunocompromised pateints
J. Antimicrob. Chemother. 1992 30: 730-731; doi:10.1093/jac/30.5.730 [PDF] [Request Permissions]  

I. ZOLFINO, S. SENESI, M. CAMPA, A. Di VITO, F. MOSCA, P. FAVINI, M. DUCCI, R. DANESI, and M. DEL TACCA

Human skin disposition of cefpodoxime after oral administration of its proxetil ester
J. Antimicrob. Chemother. 1992 30: 731-733; doi:10.1093/jac/30.5.731 [PDF] [Request Permissions]  

D. A. LEIGH

The treatment of a large outbreak of acute bacterial gastroenteritis with ciprofloxacin
J. Antimicrob. Chemother. 1992 30: 733-735; doi:10.1093/jac/30.5.733 [PDF] [Request Permissions]  

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