Journal of Antimicrobial Chemotherapy

Leading articles:

BRIAN D. HOYLE, JANA JASS, and J. WILLIAM COSTERTON

The biofilm glycocalyx as a resistance factor
J. Antimicrob. Chemother. 1990 26: 1-5; doi:10.1093/jac/26.1.1 [PDF] [Request Permissions]  

R. WISE

Macrolide progress
J. Antimicrob. Chemother. 1990 26: 5-6; doi:10.1093/jac/26.1.5 [PDF] [Request Permissions]  

Original articles:

Hannah M. Wexler and Shushan Halebian

Alterations to the penicillin-binding proteins in the Bacteroides fragilis group: a mechanism for non-ß-lactamase mediated cefoxitin resistance
J. Antimicrob. Chemother. 1990 26: 7-20; doi:10.1093/jac/26.1.7 [Abstract] [PDF] [Request Permissions]  

L. J. Chalkley and H. J. Koornhof

Intra- and inter-specific transformation of Streptococcus pneumoniae to penicillin resistance
J. Antimicrob. Chemother. 1990 26: 21-28; doi:10.1093/jac/26.1.21 [Abstract] [PDF] [Request Permissions]  

Tadahiro Oshida, Tokio Onta, Noriyuki Nakanishi, Tadahiro Matsushita, and Toutaro Yamaguchi

Activity of sub-minimal inhibitory concentrations of aspoxicillin in prolonging the postantibiotic effect against Staphylococcus aureus
J. Antimicrob. Chemother. 1990 26: 29-38; doi:10.1093/jac/26.1.29 [Abstract] [PDF] [Request Permissions]  

Kenneth V. I. Rolston, Barbara LeBlanc, Dai Hsi Ho, and Gerald P. Bodey

In-vitro activity of PD 117 596, a new quinolone, against bacterial isolates from cancer patients
J. Antimicrob. Chemother. 1990 26: 39-44; doi:10.1093/jac/26.1.39 [Abstract] [PDF] [Request Permissions]  

J. E. Barker and I. D. Farrell

The effects of single and combined antibiotics on the growth of Legionella pneumophila using time-kill studies
J. Antimicrob. Chemother. 1990 26: 45-53; doi:10.1093/jac/26.1.45 [Abstract] [PDF] [Request Permissions]  

Men-Fang Shaio and Feng-Yee Chang

Influence of cefodizime on chemotaxis and the respiratory burst in neutrophils from diabetics
J. Antimicrob. Chemother. 1990 26: 55-59; doi:10.1093/jac/26.1.55 [Abstract] [PDF] [Request Permissions]  

Eileen Ingham

Modulation of the proliferative response of murine thymocytes stimulated by IL-1, and enhancement of IL-1ß secretion from mononuclear phagocytes by tetracyclines
J. Antimicrob. Chemother. 1990 26: 61-70; doi:10.1093/jac/26.1.61 [Abstract] [PDF] [Request Permissions]  

B. Wiedemann and A. Jansen

Antibacterial activity of cefpodoxime proxetil in a pharmacokinetic in-vitro model
J. Antimicrob. Chemother. 1990 26: 71-79; doi:10.1093/jac/26.1.71 [Abstract] [PDF] [Request Permissions]  

F. Lucht, G. Dorche, G. Aubert, C. Boissier, A. M. Bertrand, and J. Brunon

The penetration of ceftriaxone into human brain tissue
J. Antimicrob. Chemother. 1990 26: 81-86; doi:10.1093/jac/26.1.81 [Abstract] [PDF] [Request Permissions]  

M. Campa, I. Zolfino, S. Senesi, N. Bernardini, R. Danesi, M. Ducci, M. Oleggini, R. Di Stefano, F. Mosca, A. Lazzarini, and M. Del Tacca

The penetration of roxithromycin into human skin
J. Antimicrob. Chemother. 1990 26: 87-90; doi:10.1093/jac/26.1.87 [Abstract] [PDF] [Request Permissions]  

A. A. Alarabi, O. Cars, B. G. Danielson, T. Salmonson, and B. Wikström

Pharmacokinetics of intravenous imipenem/cilastatin during intermittent haemofiltration
J. Antimicrob. Chemother. 1990 26: 91-98; doi:10.1093/jac/26.1.91 [Abstract] [PDF] [Request Permissions]  

Grace Sweeney, Alasdair I. Fern, Gavin Lindsay, and Malcolm W. Doig

Penetration of ciprofloxacin into the aqueous humour of the uninflamed human eye after oral administration
J. Antimicrob. Chemother. 1990 26: 99-105; doi:10.1093/jac/26.1.99 [Abstract] [PDF] [Request Permissions]  

Daphne E. Holt, John de Louvois, Rosalinde Hurley, and David Harvey

A high performance liquid chromatography system for the simultaneous assay of some antibiotics commonly found in combination in clinical samples
J. Antimicrob. Chemother. 1990 26: 107-115; doi:10.1093/jac/26.1.107 [Abstract] [PDF] [Request Permissions]  

E. J. Vollaard, H. A. L. Clasener, A. J. H. M. Janssen, and H. J. A. Wynne

Influence of cefotaxime on microbial colonization resistance in healthy volunteers
J. Antimicrob. Chemother. 1990 26: 117-123; doi:10.1093/jac/26.1.117 [Abstract] [PDF] [Request Permissions]  

Sophie Pecquet, Sophie Ravoire, and Antoine Andremont

Faecal excretion of ciprofloxacin after a single oral dose and its effect on faecal bacteria in healthy volunteers
J. Antimicrob. Chemother. 1990 26: 125-129; doi:10.1093/jac/26.1.125 [Abstract] [PDF] [Request Permissions]  

K. Dornbusch, G. H. Miller, R. S. Hare, K. J. Shaw, and the ESGAR Study Group

Resistance to aminoglycoside antibiotics in Gram-negative bacilli and staphylococci isolated from blood. Report from a European collaborative study
J. Antimicrob. Chemother. 1990 26: 131-144; doi:10.1093/jac/26.1.131 [Abstract] [PDF] [Request Permissions]  

For debate:

BARBARA E. C. BANKS

Monitoring of aminoglycosides
J. Antimicrob. Chemother. 1990 26: 145-148; doi:10.1093/jac/26.1.145 [PDF] [Request Permissions]  

Correspondence:

C. S. LEWIN and J. T. SMITH

4-Qninolones and multivalent ions
J. Antimicrob. Chemother. 1990 26: 149; doi:10.1093/jac/26.1.149 [PDF] [Request Permissions]  

M. POWELL and E. H. PRICE

Invasive infections due to Haemophilus influenzae type b resistant to ampicillin and chloramphenicol
J. Antimicrob. Chemother. 1990 26: 149-151; doi:10.1093/jac/26.1.149-a [PDF] [Request Permissions]  

S. TEHAN and Y. J. LAMB

Ciprofloxacin versus amoxycillin/clavulanic acid in the treatment of urinary tract infections in general practice
J. Antimicrob. Chemother. 1990 26: 151-152; doi:10.1093/jac/26.1.151 [PDF] [Request Permissions]  

JOHN M. B. SMITH and ZIAUDDIN S. HASHMI

Lomefloxacin disc susceptibility criteria — a reappraisal
J. Antimicrob. Chemother. 1990 26: 152-153; doi:10.1093/jac/26.1.152 [PDF] [Request Permissions]  

R. C. SPENCER and P. F. WHEAT

In-vitro activity of roxithromycin against Branhamella catarrhalis
J. Antimicrob. Chemother. 1990 26: 153-155; doi:10.1093/jac/26.1.153 [PDF] [Request Permissions]  

RICHARD EDWARDS and DAVID GREENWOOD

Antibiotic resistance in enterococci in Nottingham
J. Antimicrob. Chemother. 1990 26: 155-156; doi:10.1093/jac/26.1.155 [PDF] [Request Permissions]  

RENÉ J. COURCOL, KYUNG WON LEE, JULIE DOWNES, HANNAH M. WEXLER, ELLEN J. BARON, and SYDNEY M. FINEGOLD

In-vitro susceptibilties of Bacteroides gracilis, Fusobacterium mortiferum and F. varium to 17 antimicrobial agents
J. Antimicrob. Chemother. 1990 26: 157-158; doi:10.1093/jac/26.1.157 [PDF] [Request Permissions]  

ITZHAK BROOK

In-vitro sensitivity tests and in-vivo efficacy of cephalosporins against Bacteroides fragilis
J. Antimicrob. Chemother. 1990 26: 158-161; doi:10.1093/jac/26.1.158 [PDF] [Request Permissions]  

W. BRUMFITT, J. M. T. HAMILTON-MILLER, and W. AL-WALI

Reassessment of cefuroxime axetil for the treatment of recurrent urinary infections
J. Antimicrob. Chemother. 1990 26: 161-162; doi:10.1093/jac/26.1.161 [PDF] [Request Permissions]  

H. LUDLAM, M. DRYDEN, I. BARTON, and I. PHILLIPS

Short course ciprofloxacin therapy for CAPD peritonitis
J. Antimicrob. Chemother. 1990 26: 162-164; doi:10.1093/jac/26.1.162 [PDF] [Request Permissions]  

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