Journal of Antimicrobial Chemotherapy

Leading articles:

D. W. WARNOCK

Itraconazole and fluconazole: new drugs for deep fungal infection
J. Antimicrob. Chemother. 1989 24: 275-276; doi:10.1093/jac/24.3.275 [PDF] [Request Permissions]  

P. J. SANDERSON

Preventing infection in orthopaedic implants
J. Antimicrob. Chemother. 1989 24: 277-280; doi:10.1093/jac/24.3.277 [PDF] [Request Permissions]  

Review:

H. Mattie, W. A. Craig, and J. C. Pechèré

Determinants of efficacy and toxicity of aminoglycosides
J. Antimicrob. Chemother. 1989 24: 281-293; doi:10.1093/jac/24.3.281 [Abstract] [PDF] [Request Permissions]  

Original articles:

D. A. B. Dance, V. Wuthiekanun, W. Chaowagul, and N. J. White

The antimicrobial susceptibility of Pseudomonas pseudomallei. Emergence of resistance in vitro and during treatment
J. Antimicrob. Chemother. 1989 24: 295-309; doi:10.1093/jac/24.3.295 [Abstract] [PDF] [Request Permissions]  

D. A. B. Dance, V. Wuthiekanun, W. Chaowagul, and N. J. White

Interactions in vitro between agents used to treat melioidosis
J. Antimicrob. Chemother. 1989 24: 311-316; doi:10.1093/jac/24.3.311 [Abstract] [PDF] [Request Permissions]  

S. E. Hoffner, M. Kratz, B. Olsson-Liljequist, S. B. Svenson, and G. Källenius

In-vitro synergistic activity between ethambutol and fluorinated qoinolones against Mycobacterium avium complex
J. Antimicrob. Chemother. 1989 24: 317-324; doi:10.1093/jac/24.3.317 [Abstract] [PDF] [Request Permissions]  

F. Meunler, C. Lambert, and P. Van der Auwera

In-vitro activity of cilofungin (LY121019) in comparison with amphotericin B
J. Antimicrob. Chemother. 1989 24: 325-331; doi:10.1093/jac/24.3.325 [Abstract] [PDF] [Request Permissions]  

Janina Brajtburg, Svetlana Elberg, George S. Kobayashi, and Gerald Medoff

Effects of ascorbic add on the antifungal action of amphotericin B
J. Antimicrob. Chemother. 1989 24: 333-337; doi:10.1093/jac/24.3.333 [Abstract] [PDF] [Request Permissions]  

M. A. Arnott and J. Hay

The effect of pentamidine salts on the respiratory burst of human neutrophilic granulocytes
J. Antimicrob. Chemother. 1989 24: 339-345; doi:10.1093/jac/24.3.339 [Abstract] [PDF] [Request Permissions]  

P. Van der Auwera and M. Husson

Influence of rifampicin and ansamycin on motility and adherence of human neutrophils studied in vitro
J. Antimicrob. Chemother. 1989 24: 347-353; doi:10.1093/jac/24.3.347 [Abstract] [PDF] [Request Permissions]  

Patrice Nordmann, André Pechinot, and Antoine Kazmierczak

Cytotoxicity and uptake of pefloxacin, ciprofloxacin, and ofloxacin in primary cultures of rat hepatocytes
J. Antimicrob. Chemother. 1989 24: 355-363; doi:10.1093/jac/24.3.355 [Abstract] [PDF] [Request Permissions]  

Larry M. Baddour, Gorden D. Christensen, and Karl H. Schadow

The effect of slime production on vancomycin efficacy in the treatment of experimental endocarditis due to Staphylococcus epidermidis
J. Antimicrob. Chemother. 1989 24: 365-373; doi:10.1093/jac/24.3.365 [Abstract] [PDF] [Request Permissions]  

Eugene Leibovitz, Gershon Keren, Moshe Shabtai, Asher Barzilai, and Ethan Rubinstein

The pharmacokinetics and therapeutic efficacy of fleroxacin and pefloxacin in a rat abscess model
J. Antimicrob. Chemother. 1989 24: 375-385; doi:10.1093/jac/24.3.375 [Abstract] [PDF] [Request Permissions]  

M. Michéa-Hamzehpour and J. C. Pechère

How predictable is development of resistance after ß-lactam therapy in Enterobacter cloacae infection?
J. Antimicrob. Chemother. 1989 24: 387-395; doi:10.1093/jac/24.3.387 [Abstract] [PDF] [Request Permissions]  

Shigeru Kohno, Hironobu Koga, Keizou Yamaguchi, Miyako Masaki, Yuichi Inoue, Yasumasa Dotsu, Yasuharu Masuyama, Toshiaki Hayashi, Masaki Hirota, Atsushi Saito, and Kohei Hara

A new macrolide, TE-031 (A-56268), in treatment of experimental Legionnaires' disease
J. Antimicrob. Chemother. 1989 24: 397-405; doi:10.1093/jac/24.3.397 [Abstract] [PDF] [Request Permissions]  

Hartmut Derendorf

Pharmacokinetic evaluation of ß-lactam antibiotics
J. Antimicrob. Chemother. 1989 24: 407-413; doi:10.1093/jac/24.3.407 [Abstract] [PDF] [Request Permissions]  

K. Nye, Y. G. Shi, J. M. Andrews, J. P. Ashby, and R. Wise

The in-vitro activity, pharmacokinetics and tissue penetration of temafloxacin
J. Antimicrob. Chemother. 1989 24: 415-424; doi:10.1093/jac/24.3.415 [Abstract] [PDF] [Request Permissions]  

Denise J. Youngs, D. W. Burdon, and M. R. B. Keighley

The penetration of aztreonam, a monobactam antibiotic, into intra-abdominal abscesses
J. Antimicrob. Chemother. 1989 24: 425-429; doi:10.1093/jac/24.3.425 [Abstract] [PDF] [Request Permissions]  

Helen T. Green, Maire A.T. O'Donoghue, Malcolm D.M. Shaw, and Carol Dowling

Penetration of ceftazidime into intracranial abscess
J. Antimicrob. Chemother. 1989 24: 431-436; doi:10.1093/jac/24.3.431 [Abstract] [PDF] [Request Permissions]  

D. J. Griggs and R. Wise

A simple isocratic high-pressure liquid chromatographic assay of quinolones in serum
J. Antimicrob. Chemother. 1989 24: 437-445; doi:10.1093/jac/24.3.437 [Abstract] [PDF] [Request Permissions]  

J. C. E. Meek, F. P. V. Maesen, and B. I. Davies

A prospective study of ofloxacin in acute exacerbations of chronic respiratory disease associated with Pseudomonas aeruginosa
J. Antimicrob. Chemother. 1989 24: 447-453; doi:10.1093/jac/24.3.447 [Abstract] [PDF] [Request Permissions]  

Pekka Saloranta, Leena Roos, Erkki Elonen, and Hannu Allonen

Erythromycin ethylsuccinate, base and acistrate in the treatment of upper respiratory tract infection: two comparative studies of tolerability
J. Antimicrob. Chemother. 1989 24: 455-462; doi:10.1093/jac/24.3.455 [Abstract] [PDF] [Request Permissions]  

Correspondence:

R. SUTHERLAND

Susceptibility testing recommendations for ticarcillin/clavulanic add in me Stokes' disc diffusion test
J. Antimicrob. Chemother. 1989 24: 463-464; doi:10.1093/jac/24.3.463 [PDF] [Request Permissions]  

R. SUTHERLAND

A continuous culture system for susceptibility testing
J. Antimicrob. Chemother. 1989 24: 464; doi:10.1093/jac/24.3.464 [PDF] [Request Permissions]  

P. G. R. GODWIN and M. R. MILLAR

A continuous culture system for susceptibility testing
J. Antimicrob. Chemother. 1989 24: 464; doi:10.1093/jac/24.3.464-a [PDF] [Request Permissions]  

W. BRUMFITT, J. M. T. HAMILTON-MILLER, and R. A. GARGAN

Variation in response of Gram-positive cocci to the combination DuP 721 and ciprofloxacin
J. Antimicrob. Chemother. 1989 24: 465-466; doi:10.1093/jac/24.3.465 [PDF] [Request Permissions]  

J. E. CORKILL, C. A. HART, and P. SHEARS

Plasmid mediated ceftazidime resistance associated with a ß-lactamase giving a slow nitrocefin reaction
J. Antimicrob. Chemother. 1989 24: 467-469; doi:10.1093/jac/24.3.467 [PDF] [Request Permissions]  

P. R. SISSON, H. R. INGHAM, and P. B. CRONE

Metronidazole-resistant mutants of Escherichia coli
J. Antimicrob. Chemother. 1989 24: 470-472; doi:10.1093/jac/24.3.470 [PDF] [Request Permissions]  

Book review:

R. C. SPENCER

Book review
J. Antimicrob. Chemother. 1989 24: 475; doi:10.1093/jac/24.3.475 [PDF] [Request Permissions]  

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