Journal of Antimicrobial Chemotherapy

Leading articles:

L. J. V. PIDDOCK and R. WISE

Mechanisms of resistance to quinolones and clinical perspectives
J. Antimicrob. Chemother. 1989 23: 475-480; doi:10.1093/jac/23.4.475 [PDF] [Request Permissions]  

J. J. EARNSHAW

Prevention of infection after vascular reconstruction
J. Antimicrob. Chemother. 1989 23: 480-483; doi:10.1093/jac/23.4.480 [PDF] [Request Permissions]  

Original articles:

Victor Lorian, Jerome Ernst, and Leonard Amaral

The post-antibiotic effect defined by bacterial morphology
J. Antimicrob. Chemother. 1989 23: 485-491; doi:10.1093/jac/23.4.485 [Abstract] [PDF] [Request Permissions]  

E. Anne Eady, Jeremy I. Ross, Jonathan H. Cove, Keith T. Holland, and William J. Cunliffe

Macrolide-lincosamide-streptogramin B (MLS) resistance in cutaneous propionibacteria: definition of phenotypes
J. Antimicrob. Chemother. 1989 23: 493-502; doi:10.1093/jac/23.4.493 [Abstract] [PDF] [Request Permissions]  

D. M. Shlaes, S. Al-Obeid, J. H. Shlaes, A. Boisivon, and R. Williamson

Inducible, transferable resistance to vancomycin in Enterococcus faecium, D399
J. Antimicrob. Chemother. 1989 23: 503-508; doi:10.1093/jac/23.4.503 [Abstract] [PDF] [Request Permissions]  

P. C. Appelbaum, S. K. Spangler, E. Crotty, and M. R. Jacobs

Susceptibility of penicillin-sensitive and -resistant strains of Streptococcus pneumoniae to new antimicrobial agents, including daptomycin, teicoplanin, cefpodoxime and quinolones
J. Antimicrob. Chemother. 1989 23: 509-516; doi:10.1093/jac/23.4.509 [Abstract] [PDF] [Request Permissions]  

P. A. C. Maple, J. M. T. Hamilton-Miller, and W. Brumfitt

Comparative in-vitro activity of vancomycin, teicoplanin, ramoplanin (formerly A16686), paldimycin, DuP 721 and DuP 105 against methicillin and gentamicin resistant Staphylococcus aureus
J. Antimicrob. Chemother. 1989 23: 517-525; doi:10.1093/jac/23.4.517 [Abstract] [PDF] [Request Permissions]  

Arthur L. Barry and Ronald N. Jones

In-vitro activities of temafloxacin, tosufloxacin (A-61827) and five other fluoroquinolone agents
J. Antimicrob. Chemother. 1989 23: 527-535; doi:10.1093/jac/23.4.527 [Abstract] [PDF] [Request Permissions]  

Helen Giamarellou, Vasso Evagelopoulou, and Moses Lelekis

Enhanced in-vitro bactericidal activity of amikacin combined with latamoxef, cefotaxime and aztreonam against multi-resistant Enterobacter cloacae
J. Antimicrob. Chemother. 1989 23: 537-545; doi:10.1093/jac/23.4.537 [Abstract] [PDF] [Request Permissions]  

D. H. Stokes, M. J. Wilkinson, J. Tyler, B. Slocombe, and R. Sutherland

Bactericidal effects of amoxycillin/clavulanic acid against intracellular Legionella pneumophila in tissue culture studies
J. Antimicrob. Chemother. 1989 23: 547-556; doi:10.1093/jac/23.4.547 [Abstract] [PDF] [Request Permissions]  

M. A. Arnott and J. Hay

The effect of pentamidine salts on the in-vitro responses of neutrophilic grannlocytes
J. Antimicrob. Chemother. 1989 23: 557-564; doi:10.1093/jac/23.4.557 [Abstract] [PDF] [Request Permissions]  

G. Raponi, R. W. Vreede, M. Rozenberg-Arska, I. M. Hoepelman, N. Keller, and J. Verhoef

The influence of subminimal inhibitory concentrations of netilmicin and ceftriaxone on the interaction of Escherichia coli with host defences
J. Antimicrob. Chemother. 1989 23: 565-576; doi:10.1093/jac/23.4.565 [Abstract] [PDF] [Request Permissions]  

E. M. Veringa, D. W. Lambe, Jr, D. A. Ferguson, Jr, and J. Verhoef

Enhancement of opsonophagocytosis of Bacteroides spp. by clindamycin in subinhibitory concentrations
J. Antimicrob. Chemother. 1989 23: 577-587; doi:10.1093/jac/23.4.577 [Abstract] [PDF] [Request Permissions]  

Alicia Valadez-Salazar, Hector Guiscafre-Gallardo, Salvador Sanchez-Garcia, and Onofre Muñoz

Detection of furazolidone in human biological fluids by high performance liquid chromatography
J. Antimicrob. Chemother. 1989 23: 589-595; doi:10.1093/jac/23.4.589 [Abstract] [PDF] [Request Permissions]  

C. Y. Chan, A. W. Lam, and G. L. French

Rapid HPLC assay of fluoroquinolones in clinical specimens
J. Antimicrob. Chemother. 1989 23: 597-604; doi:10.1093/jac/23.4.597 [Abstract] [PDF] [Request Permissions]  

J. D. Grange, A. Gouyette, L. Gutmann, X. Amiot, M. D. Kitzis, S. Islam, J. F. Acar, and P. Jaillon

Pharmacokinetics of amoxycillin/clavulanic acid in serum and ascitic fluid in cirrhotic patients
J. Antimicrob. Chemother. 1989 23: 605-611; doi:10.1093/jac/23.4.605 [Abstract] [PDF] [Request Permissions]  

A. P. R. Wilson, S. Shankar, D. Felmingham, T. Treasure, and R. N. Grüneberg

Serum and tissue levels of teicoplanin during cardiac surgery: the effect of a high dose regimen
J. Antimicrob. Chemother. 1989 23: 613-617; doi:10.1093/jac/23.4.613 [Abstract] [PDF] [Request Permissions]  

P. Earl, P. R. Sisson, and H. R. Ingham

Twelve-hourly dosage schedule for oral and intravenous metronidazole
J. Antimicrob. Chemother. 1989 23: 619-621; doi:10.1093/jac/23.4.619 [Abstract] [PDF] [Request Permissions]  

F. de Lalla, G. Privitera, G. Ortisi, G. Rizzardini, D. Santoro, A. Pagano, E. Rinaldi, and P. Scarpellini

Third generation cephalosporins as a risk factor for Clostridium difficile-associated disease: a four-year survey in a general hospital
J. Antimicrob. Chemother. 1989 23: 623-631; doi:10.1093/jac/23.4.623 [Abstract] [PDF] [Request Permissions]  

E. G. Smyth, P. J. Stevens, and R. E. Holliman

Prevalence and susceptibility of highly gentamicin resistant Enterococcus faecalis in a South London teaching hospital
J. Antimicrob. Chemother. 1989 23: 633-639; doi:10.1093/jac/23.4.633 [Abstract] [PDF] [Request Permissions]  

D. Montefiore, V. O. Rotimi, and F. A. B. Adeyemi-Doro

The problem of bacterial resistance to antibiotics among strains isolated from hospital patients in Lagos and Ibadan, Nigeria
J. Antimicrob. Chemother. 1989 23: 641-651; doi:10.1093/jac/23.4.641 [Abstract] [PDF] [Request Permissions]  

Correspondence:

M. BRETT

A novel gonococcal ß-lactamase plasmid
J. Antimicrob. Chemother. 1989 23: 653-654; doi:10.1093/jac/23.4.653 [PDF] [Request Permissions]  

ROLAND N. JONES

Preliminary in-vitro studies of BMY-28232, the active metabolite of the BMY-28271 cephalosporin ester
J. Antimicrob. Chemother. 1989 23: 654-657; doi:10.1093/jac/23.4.654 [PDF] [Request Permissions]  

B. WATT

Interaction of teicoplanin with other antimicrobial agents against Gram-positive aerobes
J. Antimicrob. Chemother. 1989 23: 657-658; doi:10.1093/jac/23.4.657 [PDF] [Request Permissions]  

ROLAND N. JONES

In-vitro antimicrobial activity of enoxacin and its metabolites
J. Antimicrob. Chemother. 1989 23: 658-660; doi:10.1093/jac/23.4.658 [PDF] [Request Permissions]  

OONAGH BROGAN, PATRICIA A. GARNETT, and ROBERT BROWN

Bacteroides fragilis resistant to metronidazole, clindamycin and cefoxitin
J. Antimicrob. Chemother. 1989 23: 660-662; doi:10.1093/jac/23.4.660 [PDF] [Request Permissions]  

R. PORTMANN, C. HANSZ, R. STIGLMAYER, and E. WEIDEKAMM

Fleroxacin concentrations in myometrium, ovary and fallopian tube
J. Antimicrob. Chemother. 1989 23: 662-664; doi:10.1093/jac/23.4.662 [PDF] [Request Permissions]  

H. T. GREEN, I. J. MACKENZIE, L. DURHAM, and C. A. DOWLING

Ceftazidime in middle ear fluid
J. Antimicrob. Chemother. 1989 23: 664-666; doi:10.1093/jac/23.4.664 [PDF] [Request Permissions]  

Book review:

J. C. GINGELL

Book review
J. Antimicrob. Chemother. 1989 23: 667; doi:10.1093/jac/23.4.667 [PDF] [Request Permissions]  

Errata:

Errata
J. Antimicrob. Chemother. 1989 23: 669; doi:10.1093/jac/23.4.669 [Abstract] [PDF] [Request Permissions]  

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