Journal of Antimicrobial Chemotherapy

Leading articles:

R. WISE

The development of macrolides and related compounds
J. Antimicrob. Chemother. 1989 23: 299-300; doi:10.1093/jac/23.3.299 [PDF] [Request Permissions]  

Review:

Thomas M. Bergamini and Hiram C. Polk, Jr

The importance of tissue antibiotic activity in the prevention of operative wound infection
J. Antimicrob. Chemother. 1989 23: 301-313; doi:10.1093/jac/23.3.301 [PDF] [Request Permissions]  

Original articles:

S. M. Opal, J. M. Boyce, A. A. Medeiros, K. H. Mayer, and L. W. Lyhte

Modification of homogeneous resistance in a methicillin-resistant strain of Staphylococcus aureus by acquisition of a ß-lactamase encoding plasmid
J. Antimicrob. Chemother. 1989 23: 315-325; doi:10.1093/jac/23.3.315 [Abstract] [PDF] [Request Permissions]  

J. Zoe Jordens and Lucinda M. C. Hall

Chromosomally-encoded gentamicin resistance in ‘epidemic’ methicillin-resistant Staphylococcus aureus: detection with a synthetic oligonucleotide probe
J. Antimicrob. Chemother. 1989 23: 327-334; doi:10.1093/jac/23.3.327 [Abstract] [PDF] [Request Permissions]  

Lily Mavrommati and Era Tzelepi

Conjugal transfer of penicillin resistance plasmids to proline-citrulline-uracil dependent strains of Neisseria gonorrhoeae
J. Antimicrob. Chemother. 1989 23: 335-339; doi:10.1093/jac/23.3.335 [Abstract] [PDF] [Request Permissions]  

N. Jalil, C. Gilchrist, and D. Taylor-Robinson

Factors influencing the in-vitro sensitivity of Ureaplasma urealyticum to tetracyclines
J. Antimicrob. Chemother. 1989 23: 341-345; doi:10.1093/jac/23.3.341 [Abstract] [PDF] [Request Permissions]  

Bent L. Reder and Erne Gutschik

In-vitro activity of ciprofloxacin combined with either fusidic acid or rifampicin against Staphylococcus aureus
J. Antimicrob. Chemother. 1989 23: 347-352; doi:10.1093/jac/23.3.347 [Abstract] [PDF] [Request Permissions]  

Michael A. Martin, Michael A. Pfaller, Patricio B. Rojas, Robert F. Woolson, and Richard P. Wenzel

In-vitro susceptibility of nosocomial Gram-negative bloodstream pathogens to quinolones and other antibiotics—a statistical approach
J. Antimicrob. Chemother. 1989 23: 353-361; doi:10.1093/jac/23.3.353 [Abstract] [PDF] [Request Permissions]  

Kenneth V. I. Rolston, Barbara LeBlanc, Grace Gooch, Dai Hsi Ho, and Gerald P. Bodey

In-vitro activity of PD 117558, a new quinolone against bacterial isolates from cancer patients
J. Antimicrob. Chemother. 1989 23: 363-371; doi:10.1093/jac/23.3.363 [Abstract] [PDF] [Request Permissions]  

Robert H. K. Eng, Charles E. Cherubin, Sharon M. Smith, Frank Buccini, and Ronald Harris

In-vitro and in-vivo activity of cefpirome (HR 810) against methicillin-susceptible and -resistant Staphylococcus aureus and Streptococcus faecalis
J. Antimicrob. Chemother. 1989 23: 373-381; doi:10.1093/jac/23.3.373 [Abstract] [PDF] [Request Permissions]  

F. Soriano, C. Ponte, M. Santamaría, and C. Castilla

Effect of Bacteroides fragilis on mortality induced by Escherichia coli in an experimental infection treated with cefotaxime, aztreonam or gentamicin
J. Antimicrob. Chemother. 1989 23: 383-388; doi:10.1093/jac/23.3.383 [Abstract] [PDF] [Request Permissions]  

S. M. Navashin, I. P. Fomina, A. A. Firsov, V. M. Chernykh, and S. Kuznetsova

A dynamic model for in-vitro evaluation of antimicrobial action by simulation of the pharmacokinetic profiles of antibiotics
J. Antimicrob. Chemother. 1989 23: 389-399; doi:10.1093/jac/23.3.389 [Abstract] [PDF] [Request Permissions]  

A. Boccazzi, M. Langer, M. Mandelli, A. M. Ranzi, and R. Urso

The pharmacokinetics of aztreonam and penetration into the bronchial secretions of critically ill patients
J. Antimicrob. Chemother. 1989 23: 401-407; doi:10.1093/jac/23.3.401 [Abstract] [PDF] [Request Permissions]  

A. P. MacGowan, M. A. Greig, J. M. Andrews, D. S. Reeves, and R. Wise

Pharmacokinetics and tolerance of a new film-coated tablet of sodium fusidate administered as a single oral dose to healthy volunteers
J. Antimicrob. Chemother. 1989 23: 409-415; doi:10.1093/jac/23.3.409 [Abstract] [PDF] [Request Permissions]  

G. E. Smith, M. R. Fulford, R. W. Matthews, and D. C. E. Speller

Roxithromycin as a possible agent for prophylaxis of endocarditis: a study in normal volunteers
J. Antimicrob. Chemother. 1989 23: 417-425; doi:10.1093/jac/23.3.417 [Abstract] [PDF] [Request Permissions]  

J. A. A. Hoogkamp-Korstanje, H. A. van Bottenburg, J. van Bruggen, J. S. A. Davidson, S. J. Detmar, W. de Graaf, J. Rijnks, J. F. A. M. Ypma, and D. F. de Zwart

Treatment of chronic osteomyelitis with ciprofloxacin
J. Antimicrob. Chemother. 1989 23: 427-432; doi:10.1093/jac/23.3.427 [Abstract] [PDF] [Request Permissions]  

Giovani Acocella, André Bertrand, Jean Beytout, Jean Bernard Durrande, Jose-Anguel Garcia Rodriguez, John Kosmidis, Max Micoud, Michel Rey, Manuel Rodriguez Zapata, Jacques Roux, and Jean-Paul Stahl

Comparison of three different regimens in the treatment of acute brucellosis: a multicenter multinational study
J. Antimicrob. Chemother. 1989 23: 433-439; doi:10.1093/jac/23.3.433 [Abstract] [PDF] [Request Permissions]  

René J. Courcol, Madeleine Pinkas, and Guy R. Martin

A seven year survey of antibiotic susceptibility and its relationship with usage
J. Antimicrob. Chemother. 1989 23: 441-451; doi:10.1093/jac/23.3.441 [Abstract] [PDF] [Request Permissions]  

Correspondence:

J. M. T. HAMILTON-MILLER and J. T. SMITH

Understanding the MIC of ß-lactam antibiotics
J. Antimicrob. Chemother. 1989 23: 453; doi:10.1093/jac/23.3.453 [PDF] [Request Permissions]  

BÉATRICE SALAUZE and JEAN-CLAUDE PETIT

Paradoxical resistance to ceftazidime and aztreonam in Proteus mirabilis
J. Antimicrob. Chemother. 1989 23: 454-455; doi:10.1093/jac/23.3.454 [PDF] [Request Permissions]  

K. ROLSTON, G. GOOCH, and D. HO

In-vitro activity of clarithromycin (A-56268; TE-031) against Gram-positive bacteria
J. Antimicrob. Chemother. 1989 23: 455-457; doi:10.1093/jac/23.3.455 [PDF] [Request Permissions]  

M. K. ARORA, M. J. ROBBINS, J. HOLTON, and D. FELMINGHAM

In-vitro activity of the streptogramin group of antimicrobials against Corynebacterium jeikeium and D2 coryneform bacteria
J. Antimicrob. Chemother. 1989 23: 458-460; doi:10.1093/jac/23.3.458 [PDF] [Request Permissions]  

CARMEN BURGALETA, TERESA MORENO, and ELENA LOZA

Activity of ciprofloxacin against Escherichia coli phagocytosed by monocytes and macrophages
J. Antimicrob. Chemother. 1989 23: 460-462; doi:10.1093/jac/23.3.460 [PDF] [Request Permissions]  

R. B. FITZGEORGE and A. S. R. FEATHERSTONE

Roxithromycin therapy of experimental airborne Legionnaires' disease
J. Antimicrob. Chemother. 1989 23: 462-463; doi:10.1093/jac/23.3.462 [PDF] [Request Permissions]  

A. SHIFER, S. DANY, R. SCHWARZKOPF, and E. RUBINSTEIN

Concentrations of tetracycline in human gingival tissue in patients with chronic periodontal disease
J. Antimicrob. Chemother. 1989 23: 464-465; doi:10.1093/jac/23.3.464 [PDF] [Request Permissions]  

M. E. FRACASSO, V. CONSOLO, G. FERRONATO, R. LEONE, L. CUZZOLIN, and G. BENONI

Aztreonam penetration of bone and soft tissue, after iv infusion and bolus injection
J. Antimicrob. Chemother. 1989 23: 465-467; doi:10.1093/jac/23.3.465 [PDF] [Request Permissions]  

Errata:

Errata
J. Antimicrob. Chemother. 1989 23: 469; doi:10.1093/jac/23.3.469 [Abstract] [PDF] [Request Permissions]  

Errata
J. Antimicrob. Chemother. 1989 23: 469; doi:10.1093/jac/23.3.469-a [Abstract] [PDF] [Request Permissions]  

Book review:

DAVID A. WARRELL

Book review
J. Antimicrob. Chemother. 1989 23: 469; doi:10.1093/jac/23.3.469-b [PDF] [Request Permissions]  

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