Journal of Antimicrobial Chemotherapy

Leading articles:

J. HERITAGE and P. M. HAWKEY

Tetracycline-resistant Neisseria gonorrhoeae
J. Antimicrob. Chemother. 1988 22: 575-579; doi:10.1093/jac/22.5.575 [PDF] [Request Permissions]  

P. F. WHEAT and R. C. SPENCER

The evolution of in-vitro antimicrobial susceptibility techniques
J. Antimicrob. Chemother. 1988 22: 579-582; doi:10.1093/jac/22.5.579 [PDF] [Request Permissions]  

Meeting commentary:

D. C. E. SPELLER

The clinical impact of antibiotic resistance
J. Antimicrob. Chemother. 1988 22: 583-586; doi:10.1093/jac/22.5.583 [PDF] [Request Permissions]  

Original articles:

H. M. Champion, P. M. Bennett, D. A. Lewis, and D. S. Reeves

Cloning and characterization of an AAC(6') gene from Serratia marcescens
J. Antimicrob. Chemother. 1988 22: 587-596; doi:10.1093/jac/22.5.587 [Abstract] [PDF] [Request Permissions]  

M. L. Joly-Guillo, E. Vallée, E. Bergogne-Bérézin, and A. Philippon

Distribution of ß-lactamases and phenotype analysis in clinical strains of Acinetobacter calcoaceticus
J. Antimicrob. Chemother. 1988 22: 597-604; doi:10.1093/jac/22.5.597 [Abstract] [PDF] [Request Permissions]  

Siv G. E. Andersson and Charles G. Kurland

Effects of erythromycin base and erythromycin esters on protein synthesis in vivo in Escherichia coli
J. Antimicrob. Chemother. 1988 22: 605-612; doi:10.1093/jac/22.5.605 [Abstract] [PDF] [Request Permissions]  

A. J. de Neeling, A. Rutgers, C. S. Schot, and E. E. Stobberingh

Activity of ß-lactamase in Pseudomonas aeruginosa as studied by HPLC
J. Antimicrob. Chemother. 1988 22: 613-621; doi:10.1093/jac/22.5.613 [Abstract] [PDF] [Request Permissions]  

Patrick Boiron and Frédérique Provost

In-vitro susceptibility testing of Nocardia spp. and its taxonomic implication
J. Antimicrob. Chemother. 1988 22: 623-629; doi:10.1093/jac/22.5.623 [Abstract] [PDF] [Request Permissions]  

Dwight J. Hardy, Charles W. Hanson, Dena M. Hensey, Jill M. Beyer, and Prabhavathi B. Fernandes

Susceptibility of Campylobacter pylori to macrolides and fluoroquinolones
J. Antimicrob. Chemother. 1988 22: 631-636; doi:10.1093/jac/22.5.631 [Abstract] [PDF] [Request Permissions]  

Arthur L. Barry and Ronald N. Jones

Interpretative criteria for the agar diffusion susceptibility test with azithromycin
J. Antimicrob. Chemother. 1988 22: 637-641; doi:10.1093/jac/22.5.637 [Abstract] [PDF] [Request Permissions]  

Lennart Nilsson, Maud Nilsson, and Johan Jendle

Subpopulations of variants resistant to imipenem in Pseudomonas aeruginosa
J. Antimicrob. Chemother. 1988 22: 643-649; doi:10.1093/jac/22.5.643 [Abstract] [PDF] [Request Permissions]  

A. Boisivon, C. Guiomar, and L. Gutmann

Interaction between piperacillin and pefloxacin or amikacin on the selection of resistant mutants of Pseudomonas aeruginosa
J. Antimicrob. Chemother. 1988 22: 651-657; doi:10.1093/jac/22.5.651 [Abstract] [PDF] [Request Permissions]  

Cristina Latorre Otin, Teresa Juncosa Morros, and Isabel Sanfeliu Sala

Antibiotic susceptibility of Streptococcus pneumoniae isolates from paediatric patients
J. Antimicrob. Chemother. 1988 22: 659-665; doi:10.1093/jac/22.5.659 [Abstract] [PDF] [Request Permissions]  

C. A. Gordon, N. A. Hodges, and C. Marriott

Antibiotic interaction and diffusion through alginate and exopolysaccharide of cystic fibrosis-derived Pseudomonas aeruginosa
J. Antimicrob. Chemother. 1988 22: 667-674; doi:10.1093/jac/22.5.667 [Abstract] [PDF] [Request Permissions]  

Hendrik Pruul, Gareth Lewis, and Peter J. McDonald

Enhanced susceptibility of Gram-negative bacteria to phagocytic killing by human polymorphonuclear leucocytes after brief exposure to aztreonam
J. Antimicrob. Chemother. 1988 22: 675-686; doi:10.1093/jac/22.5.675 [Abstract] [PDF] [Request Permissions]  

Silvia E. Schliamser, Karl-Axel Broholm, Ann-Louise Liljedahl, and S. Ragnar Norrby

Comparative neurotoxicity of benzylpenicillin, imipenem/cilastatin and FCE 22101, a new injectible penem
J. Antimicrob. Chemother. 1988 22: 687-695; doi:10.1093/jac/22.5.687 [Abstract] [PDF] [Request Permissions]  

Kwang Sik Kim

Therapeutic efficacy of chloramphenicol, co-trimoxazole (trimethoprim/sulphamethoxazole), cefmenoxime and ceftriaxone in experimental bacteraemia and meningitis caused by ampicillin-resistant Huemophilus influenzae type b
J. Antimicrob. Chemother. 1988 22: 697-706; doi:10.1093/jac/22.5.697 [Abstract] [PDF] [Request Permissions]  

Maria Jimenez-Valera, Alfonso Ruiz-Bravo, Maria del Carmen Gómez, and Alberto Ramos-Cormenzana

Effect of the combination of clavulanic acid and cephalothin on an experimental infection with Yersinia enterocolitica in iron-overloaded mice
J. Antimicrob. Chemother. 1988 22: 707-713; doi:10.1093/jac/22.5.707 [Abstract] [PDF] [Request Permissions]  

Bengt Ljungberg and Ingrid Nilsson-Ehle

Pharmacokinetics of intravenous ciprofloxacin at three different doses
J. Antimicrob. Chemother. 1988 22: 715-720; doi:10.1093/jac/22.5.715 [Abstract] [PDF] [Request Permissions]  

A. P. MacGowan, M. A. Greig, E. A. Clarke, L. O. White, and D. S. Reeves

The pharmacokinetics of norfloxacin in the aged
J. Antimicrob. Chemother. 1988 22: 721-727; doi:10.1093/jac/22.5.721 [Abstract] [PDF] [Request Permissions]  

Cliodna A. M. McNulty, J. C. Dent, G. A. Ford, and S. P. Wilkinson

Inhibitory antimicrobial concentrations against Campylobacter pylori in gastric mucosa
J. Antimicrob. Chemother. 1988 22: 729-738; doi:10.1093/jac/22.5.729 [Abstract] [PDF] [Request Permissions]  

L. O. White, R. Edwards, H. A. Holt, A. M. Lovering, R. G. Finch, and D. S. Reeves

The in-vitro degradation at 37°C of vancomycin in serum, CAPD fluid and phosphate-buffered saline
J. Antimicrob. Chemother. 1988 22: 739-745; doi:10.1093/jac/22.5.739 [Abstract] [PDF] [Request Permissions]  

E. J. Vollaard, H. A. L. Clasener, A. J. A. van Griethuysen, A. J. H. M. Janssen, A. H. J. Sanders-Reijmers, N. F. Muller, and P. J. C. Huige

Influence of cefaclor, phenethicillin, co-trimoxazole and doxycycine on colonization resistance in healthy volunteers
J. Antimicrob. Chemother. 1988 22: 747-758; doi:10.1093/jac/22.5.747 [Abstract] [PDF] [Request Permissions]  

R. A. Barnes and T. R. Rogers

Response rates to a staged antibiotic regimen in febrile neutropenic patients
J. Antimicrob. Chemother. 1988 22: 759-763; doi:10.1093/jac/22.5.759 [Abstract] [PDF] [Request Permissions]  

Raymond Liang, Raymond Yung, P. Y. Chau, T. K. Chan, W. K. Lam, S. Y. So, and David Todd

Imipenem/cilastatin as initial therapy for febrile neutropenic patients
J. Antimicrob. Chemother. 1988 22: 765-770; doi:10.1093/jac/22.5.765 [Abstract] [PDF] [Request Permissions]  

Correspondence:

E. B. KACZMARSKI

Mupirocin in polyethylene glycol base is not suitable for application to burns
J. Antimicrob. Chemother. 1988 22: 771; doi:10.1093/jac/22.5.771 [PDF] [Request Permissions]  

W. C. NOBLE, MARY RAHMAN, B. COOKSON, and I. PHILLIPS

Transferable mupirocin-resistance
J. Antimicrob. Chemother. 1988 22: 771-772; doi:10.1093/jac/22.5.771-a [PDF] [Request Permissions]  

DONALD J. POHLOD

Susceptibility of Legionella pneumophila to AZT
J. Antimicrob. Chemother. 1988 22: 772-773; doi:10.1093/jac/22.5.772 [PDF] [Request Permissions]  

MOHAMMAD BAKHTIAR and SYDNEY SELWYN

Combination of aztreonam with anti-staphylococcal antibiotics
J. Antimicrob. Chemother. 1988 22: 773-774; doi:10.1093/jac/22.5.773 [PDF] [Request Permissions]  

C. EDWARDS and D. K. SCOTT

Optimal blood sampling time for gentamicin
J. Antimicrob. Chemother. 1988 22: 774-776; doi:10.1093/jac/22.5.774 [PDF] [Request Permissions]  

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