Journal of Antimicrobial Chemotherapy

Leading articles:

STEPHEN R. ALCOCK and IAIN McA. LEDINGHAM

Selective decontamination of the digestive tract and prevention of infection in intensive care units
J. Antimicrob. Chemother. 1988 22: 97-104; doi:10.1093/jac/22.2.97 [PDF] [Request Permissions]  

A. M. EMMERSON

Cefuroxime axetil
J. Antimicrob. Chemother. 1988 22: 101-104; doi:10.1093/jac/22.2.101 [PDF] [Request Permissions]  

Original articles:

T. H. Farmer and C. Reading

The effects of clavulanic acid and sulbactam on ß-lactamase biosynthesis
J. Antimicrob. Chemother. 1988 22: 105-111; doi:10.1093/jac/22.2.105 [Abstract] [PDF] [Request Permissions]  

Mohamed Shohayed and Ian Chopra

Multiple isoelectric forms of bacterial penicillin-binding proteins: artefacts or genuine cellular components?
J. Antimicrob. Chemother. 1988 22: 113-118; doi:10.1093/jac/22.2.113 [Abstract] [PDF] [Request Permissions]  

J. O. Jarlev, V. Thamdrup Rosdahl, I. Mortensen, and M. Weis Bentzon

In-vitro activity and ß-lactamase stability of methicillin, isoxazolyl penicillins and cephalothin against coagulase-negative staphylococci
J. Antimicrob. Chemother. 1988 22: 119-125; doi:10.1093/jac/22.2.119 [Abstract] [PDF] [Request Permissions]  

Hannu Korkeala and Pekka T. Männistö

Time course of the antibacterial activity of erythromycin stearate and erythromycin acistrate against two Staphylococcus aureus strains in vitro
J. Antimicrob. Chemother. 1988 22: 127-133; doi:10.1093/jac/22.2.127 [Abstract] [PDF] [Request Permissions]  

Anna King, Carole Boothman, and Ian Phillips

The in-vitro activity of PD127,391, a new quinolone
J. Antimicrob. Chemother. 1988 22: 135-141; doi:10.1093/jac/22.2.135 [Abstract] [PDF] [Request Permissions]  

Masahiro Takahata, Masako Otsuki, and Takeshi Nishino

In-vitro and in-vivo activities of T-3262, a new pyridone carboxylic acid
J. Antimicrob. Chemother. 1988 22: 143-154; doi:10.1093/jac/22.2.143 [Abstract] [PDF] [Request Permissions]  

C. Cao, N. X. Chin, and H. C. Neu

In-vitro activity and ß-lactamase stability of LY163892
J. Antimicrob. Chemother. 1988 22: 155-165; doi:10.1093/jac/22.2.155 [Abstract] [PDF] [Request Permissions]  

P. N. Levett

Antimicrobial susceptibility of Clostridium difficile determined by disc diffusion and breakpoint methods
J. Antimicrob. Chemother. 1988 22: 167-173; doi:10.1093/jac/22.2.167 [Abstract] [PDF] [Request Permissions]  

Evelio J. Perea, Encarna Clavijo, M. Carmen Nogales, and Isabel Garc{acute}a Luque

Interaction of aminoglycosides and cephalosporins against Pseudomonas aeruginosa. Correlation between interaction index and killing curve
J. Antimicrob. Chemother. 1988 22: 175-183; doi:10.1093/jac/22.2.175 [Abstract] [PDF] [Request Permissions]  

P. Van der Auwera, T. Matsumoto, and M. Husson

Intraphagocytic penetration of antibiotics
J. Antimicrob. Chemother. 1988 22: 185-192; doi:10.1093/jac/22.2.185 [Abstract] [PDF] [Request Permissions]  

Massimo Fantoni, Enrica Tamburrini, Federico Pallavicini, Andrea Antinori, and Properzio Nervo

Influence of ofloxacin and pefloxacin on human lymphocyte immunoglobulin secretion and on polymorphonuclear leucocyte superoxide anion production
J. Antimicrob. Chemother. 1988 22: 193-196; doi:10.1093/jac/22.2.193 [Abstract] [PDF] [Request Permissions]  

I. De Lepeleire, A. Van Hecken, R. Verbesselt, T. B. Tjandra-Maga, and P. J. De Schepper

Comparative oral pharmacokinetics of fleroxacin and pefloxacin
J. Antimicrob. Chemother. 1988 22: 197-202; doi:10.1093/jac/22.2.197 [Abstract] [PDF] [Request Permissions]  

R. Wise, D. Honeybourne, J. M. Andrews, and J. P. Ashby

The penetration of fleroxacin into bronchial mucosa
J. Antimicrob. Chemother. 1988 22: 203-206; doi:10.1093/jac/22.2.203 [Abstract] [PDF] [Request Permissions]  

Kan-etsu Okura, Tsunekazu Haruta, and Yutaka Kobayashi

Drug transfer into cerebrospinal fluid after simultaneous administration of ampicillin with ceftriaxone or ceftazidime in rabbits with Staphylococcus aureus meningitis
J. Antimicrob. Chemother. 1988 22: 207-211; doi:10.1093/jac/22.2.207 [Abstract] [PDF] [Request Permissions]  

C. Brattström, A.-S. Malmborg, and G. Tydén

Penetration of ciprofloxacin and ofloxacin into human allograft pancreatic juice
J. Antimicrob. Chemother. 1988 22: 213-219; doi:10.1093/jac/22.2.213 [Abstract] [PDF] [Request Permissions]  

Report from a Swedish Study Group

Therapy of acute and chronic Gram-negative osteomyelitis with ciprofloxacin
J. Antimicrob. Chemother. 1988 22: 221-228; doi:10.1093/jac/22.2.221 [Abstract] [PDF] [Request Permissions]  

F. P. V. Maesen, B. I. Davies, C. Baur, and C. A. Sumajow

Cefodizime in acute purulent exacerbations of chronic respiratory disease
J. Antimicrob. Chemother. 1988 22: 229-235; doi:10.1093/jac/22.2.229 [Abstract] [PDF] [Request Permissions]  

Roger Sage, Ian Hann, H. Grant Prentice, Stephen Devereux, Robert Corringham, A. Victor Hoffbrand, Hilary Blacklock, Louise Stirling, Maria Guimaraes, Eleftheria Trikka, Amrat Bhamra, Pauline Warner, and Paul Noone

A randomized trial of empirical antibiotic therapy with one of four ß-lactam antibiotics in combination with netilmicin in febrile neutropenic patients
J. Antimicrob. Chemother. 1988 22: 237-247; doi:10.1093/jac/22.2.237 [Abstract] [PDF] [Request Permissions]  

J. Heritage, G. W. Dyke, D. Johnston, and R. W. Lacey

Selection of resistance to gentamicin and netilmicin in the faecal flora following prophylaxis for cob-rectal surgery
J. Antimicrob. Chemother. 1988 22: 249-256; doi:10.1093/jac/22.2.249 [Abstract] [PDF] [Request Permissions]  

A. W. Sturm

Rational use of antimicrobial agents and diagnostic microbiology facilities
J. Antimicrob. Chemother. 1988 22: 257-260; doi:10.1093/jac/22.2.257 [Abstract] [PDF] [Request Permissions]  

Correspondence:

F. J. MORAN, C. PEREZ, C. HURTADO, M. T. BLANCO, and J. PRIETO

Enhancement of antimicrobial activity of metronidazole in mixed cultures of Bacteroides fragilis and Escherickia coli
J. Antimicrob. Chemother. 1988 22: 261-262; doi:10.1093/jac/22.2.261 [PDF] [Request Permissions]  

A. KHARAZMI and H. NIELSEN

Fusidic acid and human phagocyte function
J. Antimicrob. Chemother. 1988 22: 262-263; doi:10.1093/jac/22.2.262 [PDF] [Request Permissions]  

M. DRANCOURT, H. GALLAIS, D. RAOULT, E. ESTRANGIN, M. N. MALLET, and P. DE MICCO

Ofloxacin penetration into cerobrospinal fluid
J. Antimicrob. Chemother. 1988 22: 263-265; doi:10.1093/jac/22.2.263 [PDF] [Request Permissions]  

R. BAYSTON

CSF vancomycin concentrations
J. Antimicrob. Chemother. 1988 22: 265; doi:10.1093/jac/22.2.265 [PDF] [Request Permissions]  

ROSEMARY ROONEY, MAURICE C. NELIGAN, ROSEMARY HONE, and ANTHONY MURRAY

Serum concentrations of cephalosporins and the cell saver in cardiopulmonary bypass surgery
J. Antimicrob. Chemother. 1988 22: 266-268; doi:10.1093/jac/22.2.266 [PDF] [Request Permissions]  

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