Journal of Antimicrobial Chemotherapy

Leading articles:

BERNARD D. DAVIS

The lethal action of aminoglycoside
J. Antimicrob. Chemother. 1988 22: 1-3; doi:10.1093/jac/22.1.1 [PDF] [Request Permissions]  

The Garrod Lecture:

George N. Rolinson

The influence of 6-aminopenicillanic acid on antibiotic development
J. Antimicrob. Chemother. 1988 22: 5-14; doi:10.1093/jac/22.1.5 [PDF] [Request Permissions]  

Original articles:

Jürg Blaser and Ruedi Lüthy

Comparative study on antagonistic effects of low pH and cation supplementation on in-vitro activity of quinolones and aminoglycosides against Pseudomonas aeruginosa
J. Antimicrob. Chemother. 1988 22: 15-22; doi:10.1093/jac/22.1.15 [Abstract] [PDF] [Request Permissions]  

Barbro Isaksson, Lennart Nilsson, Rolf Maller, and Lars Sör{acute}n

Postantibiotic effect of aminoglycosides on Gram-negative bacteria evaluated by a new method
J. Antimicrob. Chemother. 1988 22: 23-33; doi:10.1093/jac/22.1.23 [Abstract] [PDF] [Request Permissions]  

J. M. T. Hamilton-Miller

Reversal of activity of trimethoprim against Gram-positive cocci by thymidine, thymine and ‘folates’
J. Antimicrob. Chemother. 1988 22: 35-39; doi:10.1093/jac/22.1.35 [Abstract] [PDF] [Request Permissions]  

Vincent M. Figueredo and Harold C. Neu

Synergy of ciprofloxacin with fosfomycin in vitro against Pseudomonas isolates from patients with cystic fibrosis
J. Antimicrob. Chemother. 1988 22: 41-50; doi:10.1093/jac/22.1.41 [Abstract] [PDF] [Request Permissions]  

Jan Renneberg and Mats Walder

A mouse model for simultaneous pharmacokinetic and efficacy studies of antibiotics at sites of infection
J. Antimicrob. Chemother. 1988 22: 51-60; doi:10.1093/jac/22.1.51 [Abstract] [PDF] [Request Permissions]  

Endre Ludwig, Éva Székely, András Csiba, and Hedvig Graber

The effect of ciprofloxacin on antipyrine metabolism
J. Antimicrob. Chemother. 1988 22: 61-67; doi:10.1093/jac/22.1.61 [Abstract] [PDF] [Request Permissions]  

S. T. Fan, W. Y. Lau, C. H. Teoh-Chan, K. F. Lau, and E. H. Mauracher

Once daily administration of netilmicin compared with thrice daily, both in combination with metronidazole, in gangrenous and perforated appendicitis
J. Antimicrob. Chemother. 1988 22: 69-74; doi:10.1093/jac/22.1.69 [Abstract] [PDF] [Request Permissions]  

R. Maller, B. Isaksson, L. Nilsson, and L. Sörén

A study of amikacin given once versus twice daily in serious infections
J. Antimicrob. Chemother. 1988 22: 75-79; doi:10.1093/jac/22.1.75 [Abstract] [PDF] [Request Permissions]  

Correspondence:

C. CHANAL, R. LABIA, and D. SIROT

Novel plasmid-mediated ceftazidimase from Klebsiella pneumoniae isolates
J. Antimicrob. Chemother. 1988 22: 81-82; doi:10.1093/jac/22.1.81 [PDF] [Request Permissions]  

M. KETTNER, T. MACICKOVÅ, V. KRCMÉRY, and J. HAVLÍK

Mechanisms of transferable amikacin resistance in enterobacteria in a Czechoslovak clinic
J. Antimicrob. Chemother. 1988 22: 82-84; doi:10.1093/jac/22.1.82 [PDF] [Request Permissions]  

J. WILSON, J. DURODIE, and M. FOULSTONE

Hydrolysis of semi-synthetic macrolides by erythromycin esterase from Escherichia coli
J. Antimicrob. Chemother. 1988 22: 84-86; doi:10.1093/jac/22.1.84 [PDF] [Request Permissions]  

ROBERTA FONTANA

Activity of penems against methidillin-resistant Staphylococcus aureus
J. Antimicrob. Chemother. 1988 22: 86; doi:10.1093/jac/22.1.86 [PDF] [Request Permissions]  

H. A. HOLT, M. J. BYWATER, and D. S. REEVES

Activity of penems against methidillin-resistant Staphylococcus aureus
J. Antimicrob. Chemother. 1988 22: 87-88; doi:10.1093/jac/22.1.87 [PDF] [Request Permissions]  

I. M. GOULD, J. S. LEGGE, and T. M. S. REID

Amoxycillin/clavulanic acid levels in lower respiratory secretions
J. Antimicrob. Chemother. 1988 22: 88-89; doi:10.1093/jac/22.1.88 [PDF] [Request Permissions]  

J. J. ANDREASEN, S. MØLLER, O. HAUCH, L. N. JØRGENSEN, A. LESTER, I. MORTENSEN, and V. F. THOMSEN

Peroperative concentrations of cefuroxime in serum and subcutaneous tissue following antimicrobial prophylaxis in gastrointestinal surgery
J. Antimicrob. Chemother. 1988 22: 90-92; doi:10.1093/jac/22.1.90 [PDF] [Request Permissions]  

J. W. STONE, R. WISE, I. A. DONOVAN, and J. GEARTY

Failure of ciprofloxacin to eradicate Campylobacter pylori from the stomach
J. Antimicrob. Chemother. 1988 22: 92-93; doi:10.1093/jac/22.1.92 [PDF] [Request Permissions]  

Book review:

G. M. S. SCOTT

Book review
J. Antimicrob. Chemother. 1988 22: 95; doi:10.1093/jac/22.1.95 [PDF] [Request Permissions]  

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