Journal of Antimicrobial Chemotherapy

Leading articles:

P. M. HAWKEY

The molecular evolution of antibiotic resistance genes in Gram-negative bacteria
J. Antimicrob. Chemother. 1986 18: 147-149; doi:10.1093/jac/18.2.147 [PDF] [Request Permissions]  

W. A. GILLESPIE

Antibiotics in catheterized patients
J. Antimicrob. Chemother. 1986 18: 149-151; doi:10.1093/jac/18.2.149 [PDF] [Request Permissions]  

Original articles:

M. J. Rivera, J. Castillo, C. Martin, M. Navarro, and R. Gomez-Lus

Aminoglycoside-phosphotransferases APH(3')-IV and APH(3'') synthesized by a strain of Campylobacter coli
J. Antimicrob. Chemother. 1986 18: 153-158; doi:10.1093/jac/18.2.153 [Abstract] [PDF] [Request Permissions]  

Kenneth V. I. Rolston, Maria Elena Alvarez, Jennifer F. Hoy, Helen C. Alderman, Dah Hsi Ho, and Gerald P. Bodey

In-vitro activity of Sch 34343, a new penam, against Gram-positive isolates from cancer patients
J. Antimicrob. Chemother. 1986 18: 159-162; doi:10.1093/jac/18.2.159 [Abstract] [PDF] [Request Permissions]  

Anna King, Kevin Shannon, Jayne Slegg, and Ian Phillips

The in-vitro activity of CI-934 compared with that of other new 4-quinolones and nalidixic acid
J. Antimicrob. Chemother. 1986 18: 163-169; doi:10.1093/jac/18.2.163 [Abstract] [PDF] [Request Permissions]  

Mark G. Thomas and Selwyn D. R. Lang

In-vitro activity of coumermycin against methicillin-resistant staphylococci: a comparison with six other agents
J. Antimicrob. Chemother. 1986 18: 171-175; doi:10.1093/jac/18.2.171 [Abstract] [PDF] [Request Permissions]  

Michael R. Jacobs, Stephen C. Aronoff, Sharon Johenning, and Shigeru Yamabe

Comparative activities of the ß-lactamase inhibitors YTR 830, clavulanate and sulbactam combined with extended-spectrum penicillins against ticarcillin-resistant Enterobacteriaceae and pseudomonads
J. Antimicrob. Chemother. 1986 18: 177-184; doi:10.1093/jac/18.2.177 [Abstract] [PDF] [Request Permissions]  

A. A. Miles, J. P. Maskell, and S. J. W. Evans

The quantification of the neutralization of the action of antibiotics by cationic iron
J. Antimicrob. Chemother. 1986 18: 185-193; doi:10.1093/jac/18.2.185 [Abstract] [PDF] [Request Permissions]  

G. Haroche, A. Salvanet, Ch. Lafaix, Ph. Dubayle, F. Forestier, A. Meulmans, and T. Lang

Phamacokinetics of aztreonam in the aqueous humour
J. Antimicrob. Chemother. 1986 18: 195-198; doi:10.1093/jac/18.2.195 [Abstract] [PDF] [Request Permissions]  

A. Salvanet, A Fisch, C. Lafaix, G Montay, P. Dubayle, F. Forestier, and G. Harocbe

Pefloxacin concentrations in human aqueous humour and lens
J. Antimicrob. Chemother. 1986 18: 199-201; doi:10.1093/jac/18.2.199 [Abstract] [PDF] [Request Permissions]  

Jean-Paul Fillastre, Jean-Bernard Fourtillan, Annie Leroy, Nicole Ramis, Marc-André Lefevre, Georges Reumont, and Guy Humbert

Pharmacokinetics of cefonicid in uraemic patients
J. Antimicrob. Chemother. 1986 18: 203-211; doi:10.1093/jac/18.2.203 [Abstract] [PDF] [Request Permissions]  

Mamoun A. Homeida, Tawfique K. Daneshmend, Hassan M. Ali, and Clive M. Kaye

Metronidazole metabolism following oral benzoylmetronidazole suspension in children with giardiasis
J. Antimicrob. Chemother. 1986 18: 213-219; doi:10.1093/jac/18.2.213 [Abstract] [PDF] [Request Permissions]  

Bo Norberg and Håkan Blom

A morphometrical analysis of the effect of a single therapeutic oral dose of doxycycline on cell membrane area of neutrophil polymorphonuclear leucocytes
J. Antimicrob. Chemother. 1986 18: 221-226; doi:10.1093/jac/18.2.221 [Abstract] [PDF] [Request Permissions]  

P. Vowden, J. Stewart, B. Fowler, C. H. Ramsden, and R. C. Kester

The concentration of latamoxef achieved in the bile and gallbladder wall of patients with cholecystitis
J. Antimicrob. Chemother. 1986 18: 227-232; doi:10.1093/jac/18.2.227 [Abstract] [PDF] [Request Permissions]  

M. T. Labro, C. Babin-Chevaye, and J. Hakim

Effects of cefotaxime and cefodizime on human granulocyte functions in vitro
J. Antimicrob. Chemother. 1986 18: 233-237; doi:10.1093/jac/18.2.233 [Abstract] [PDF] [Request Permissions]  

Kyoko Iida-Tanaka, Terukazu Tanaka, Shozo Irino, and Ariaki Nagayama

Enhanced bactericidal action of mouse macrophages by subinhibitory concentrations of monobactams
J. Antimicrob. Chemother. 1986 18: 239-250; doi:10.1093/jac/18.2.239 [Abstract] [PDF] [Request Permissions]  

Atsushi Saito, Hironobu Koga, Hideaki Shigeno, Koichi Watanabe, Kenji Mori, Shigeru Kohno, Yoshiteru Shigeno, Yoji Suzuyama, Keizo Yamaguchi, Masaki Hirota, and Kohel Hara

The antimicrobial activity of ciprofloxacin against Legionella species and the treatment of experimental Legionella pneumonia in guinea pigs
J. Antimicrob. Chemother. 1986 18: 251-260; doi:10.1093/jac/18.2.251 [Abstract] [PDF] [Request Permissions]  

Elsa Palou de Fernandez, Maria Mercedes Patino, John R. Graybill, and Michael H. Tarbit

Treatment of cryptococcal meningitis in mice with fluconazole
J. Antimicrob. Chemother. 1986 18: 261-270; doi:10.1093/jac/18.2.261 [Abstract] [PDF] [Request Permissions]  

Stephen C. Aronoff, Michael R. Jacobs, Pauline H. Labrozzi, and Shigeru Yamabe

Synergy of amoxycillin combined with clavulanate and YTR 830 in experimental infections in mice
J. Antimicrob. Chemother. 1986 18: 271-276; doi:10.1093/jac/18.2.271 [Abstract] [PDF] [Request Permissions]  

P. Gargalianos, P. T. Jackson, C. Herzog, and A. M. Geddes

Trimethoprim in enteric fever
J. Antimicrob. Chemother. 1986 18: 277-279; doi:10.1093/jac/18.2.277 [Abstract] [PDF] [Request Permissions]  

B. E. Storey and B. I. Davies

A simple computer program for calculating areas under concentration-time curves
J. Antimicrob. Chemother. 1986 18: 281-285; doi:10.1093/jac/18.2.281 [Abstract] [PDF] [Request Permissions]  

Correspondence:

DAVID GREENWOOD

Phenotypic resistance
J. Antimicrob. Chemother. 1986 18: 287; doi:10.1093/jac/18.2.287 [PDF] [Request Permissions]  

JOHN-ERIK BRORSON and PETER LARSSON

Sub MIC levels of cefoxitin and imipenem affect disc diffusion zone diameters to cefotaxime, ceftazidime, piperacillin and imipenem for Pseudomonas aeruginosa
J. Antimicrob. Chemother. 1986 18: 287-289; doi:10.1093/jac/18.2.287-a [PDF] [Request Permissions]  

T. K. DANESHMEND, A. R. MASON, C. H. LOWE, D. W. WARNOCK, and E. M. JOHNSON

Influence of formulation on ketoconazole pharmacokinetics in man: comparison of standard tablet versus capsule containing citric acid
J. Antimicrob. Chemother. 1986 18: 289-291; doi:10.1093/jac/18.2.289 [PDF] [Request Permissions]  

P. J. THULUVATH and M. W. MCKENDRICK

Nitrofurantoin induced chronic liver disease
J. Antimicrob. Chemother. 1986 18: 291-292; doi:10.1093/jac/18.2.291-a [PDF] [Request Permissions]  

Errata:

Erratum
J. Antimicrob. Chemother. 1986 18: 291; doi:10.1093/jac/18.2.291 [Abstract] [PDF] [Request Permissions]  

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