Journal of Antimicrobial Chemotherapy

Leading articles:

ERIK DE CLERCQ

Current leads in antiviral chemotherapy
J. Antimicrob. Chemother. 1986 17: 399-402; doi:10.1093/jac/17.4.399 [PDF] [Request Permissions]  

WILLIAM H. BEGGS

Mechanisms of synergistic interactions between amphotericin B and flucytosine
J. Antimicrob. Chemother. 1986 17: 402-404; doi:10.1093/jac/17.4.402 [PDF] [Request Permissions]  

R. C. SPENCER and P. F. WHEAT

Novel mechanisms for determining antibiotic susceptibilities
J. Antimicrob. Chemother. 1986 17: 404-407; doi:10.1093/jac/17.4.404 [PDF] [Request Permissions]  

Original articles:

V. Barr, K. Barr, M. R. Millar, and R. W. Lacey

ß-Lactam antibiotics increase the frequency of plasmid transfer in Staphylococcus aureus
J. Antimicrob. Chemother. 1986 17: 409-413; doi:10.1093/jac/17.4.409 [Abstract] [PDF] [Request Permissions]  

Alain M. Philippon, Gerard C. Paul, and George A. Jacoby

New plasmid-mediated oxacillin-hydrolyzing ß-lactamase in Pseudomonas aeruginosa
J. Antimicrob. Chemother. 1986 17: 415-422; doi:10.1093/jac/17.4.415 [Abstract] [PDF] [Request Permissions]  

E. M. Scott, S. P. Gorman, J. S. Millership, and L. R. Wright

Effect of miconazole and clotrimazole on K⁺ release and inhibition of ergosterol biosynthesis in Trichophyton mentagrophytes and related ultrastructural observations
J. Antimicrob. Chemother. 1986 17: 423-432; doi:10.1093/jac/17.4.423 [Abstract] [PDF] [Request Permissions]  

Masafumi Nakao, Masahiro Kondo, and Akira Imada

Bactericidal and bacteriolytic activities of carumonam and its effect on bacterial morphology
J. Antimicrob. Chemother. 1986 17: 433-439; doi:10.1093/jac/17.4.433 [Abstract] [PDF] [Request Permissions]  

Harold C. Neu, Nai-Xun Chin, Kethy Jules, and Porupen Labthavikul

The activity of BMY 28142 a new broad spectrum ß-lactamase stable cephalosporin
J. Antimicrob. Chemother. 1986 17: 441-452; doi:10.1093/jac/17.4.441 [Abstract] [PDF] [Request Permissions]  

Kenneth V. I. Rolston, Maria E. Alvarez, Kou-Ching Hsu, and Gerald P. Bodey

In-vitro activity of cefpirome (HR-810), WIN-49375, BMY-28142 and other antibiotics against nosocomially important isolates from cancer patients
J. Antimicrob. Chemother. 1986 17: 453-457; doi:10.1093/jac/17.4.453 [Abstract] [PDF] [Request Permissions]  

J. Bosch, J. Linares, M. J. López de Goicoechea, J. Ariza, M. C. Cisnal, and R. Martin

In-vitro activity of ciprofloxacin, ceftriaxone and five other antimicrobial agents against 95 strains of Brucella melitensis
J. Antimicrob. Chemother. 1986 17: 459-461; doi:10.1093/jac/17.4.459 [Abstract] [PDF] [Request Permissions]  

Kenneth E. Aldridge, Charles V. Sanders, and Robert L. Marier

Variation in the potentiation of ß-lactam antibiotic activity by clavulanic acid and sulbactam against multiply antibiotic-resistant bacteria
J. Antimicrob. Chemother. 1986 17: 463-469; doi:10.1093/jac/17.4.463 [Abstract] [PDF] [Request Permissions]  

A. A. Miles and J. P. Maskell

The neutralization of antibiotic action by metallic cations and iron chelators
J. Antimicrob. Chemother. 1986 17: 481-487; doi:10.1093/jac/17.4.481 [Abstract] [PDF] [Request Permissions]  

J. Climax, T. J. Lenehan, R. Lambe, M. Kenny, E. Caffrey, and A. Darragh

Interaction of antimicrobial agents with human peripheral blood leucocytes: uptake and intracellular localization of certain sulphonamides and trimethoprims
J. Antimicrob. Chemother. 1986 17: 489-498; doi:10.1093/jac/17.4.489 [Abstract] [PDF] [Request Permissions]  

K. P. Fu, N. Hetzel, P. P. Hung, and F. J. Gregory

Synergistic activity of apalcillin and gentamicin in a combination therapy in experimental Pseudomonas bacteraemia of neutropenic mice
J. Antimicrob. Chemother. 1986 17: 499-503; doi:10.1093/jac/17.4.499 [Abstract] [PDF] [Request Permissions]  

Svend Stenvang Pedersen, Christian Koch, Niels Heiby, and Kirsten Rosendal

An epidemic spread of multiresistant Pseudomonas aeruginosa in a cystic fibrosis centre
J. Antimicrob. Chemother. 1986 17: 505-516; doi:10.1093/jac/17.4.505 [Abstract] [PDF] [Request Permissions]  

K. G. Naber, G. A. Dette, F. Kees, H. Knothe, and H. Grobeckert

Pharmacokinetics, in-vitro activity, therapeutic efficacy and clinical safety of aztreonam vs. cefotaxime in the treatment of complicated urinary tract infections
J. Antimicrob. Chemother. 1986 17: 517-527; doi:10.1093/jac/17.4.517 [Abstract] [PDF] [Request Permissions]  

Tania Pressler, Svend Stenvang Pedersen, Lene Christiansen, Marta Szaff, Christian Koch, and Niels Hoiby

Sultamicillin—a new antibiotic in the treatment of persistent lower respiratory tract infections caused by Haemophilus influenzae
J. Antimicrob. Chemother. 1986 17: 529-533; doi:10.1093/jac/17.4.529 [Abstract] [PDF] [Request Permissions]  

D. Isaacs, M. P. E. Slack, A. R. Wilkinson, and A. W. Westwood

Successful treatment of pseudomonas ventriculitis with ciprofloxacin
J. Antimicrob. Chemother. 1986 17: 535-538; doi:10.1093/jac/17.4.535 [Abstract] [PDF] [Request Permissions]  

Articles:

Jos A. M. van de Klundert, Mariëtte H. van Gestel, Els van Doom, and R. Peter Mouton

Disc diffusion test for the determination of semi-quantitative substrate profiles of ß-lactamases
J. Antimicrob. Chemother. 1986 17: 471-479; doi:10.1093/jac/17.4.471 [Abstract] [PDF] [Request Permissions]  

Correspondence:

R. H. GEORGE

The influence of protein binding on the antistaphylococcal activity of antibiotics
J. Antimicrob. Chemother. 1986 17: 539-540; doi:10.1093/jac/17.4.539 [PDF] [Request Permissions]  

D. J. POHLOD and L. D. SARAVOLATZ

Activity of quinolones against Legionellaceae
J. Antimicrob. Chemother. 1986 17: 540-541; doi:10.1093/jac/17.4.540 [PDF] [Request Permissions]  

A. L. BARRY, R. N. JONES, L. W. AYERS, T. L. GAVAN, and E. H. GERLACH

Activity of temocillin and ticarcillin against consecutively isolated Enterobacteriaceae in four medical centres
J. Antimicrob. Chemother. 1986 17: 541-542; doi:10.1093/jac/17.4.541 [PDF] [Request Permissions]  

B. I. DAVIES and F. P. V. MAESEN

Aminopenicillins and superinfection by Gram-negative rods
J. Antimicrob. Chemother. 1986 17: 543-544; doi:10.1093/jac/17.4.543 [PDF] [Request Permissions]  

R. WALDRON, D. G. ARKELL, R. WISE, and J. M. ANDREWS

The intraprostatic penetration of ciprofloxacin
J. Antimicrob. Chemother. 1986 17: 544-545; doi:10.1093/jac/17.4.544 [PDF] [Request Permissions]  

F. LUCHT, S. TIGAUD, M. BRUN, Ph. MAHUL, D. PEYRAMOND, and J. L. BERTRAND

Penetration of ceftriaxone into the liver
J. Antimicrob. Chemother. 1986 17: 545-546; doi:10.1093/jac/17.4.545 [PDF] [Request Permissions]  

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