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Contents: Volume 15, Supplement A, 1985   [Index by Author] 


Down Other Departments
Down In-Vitro Factors Affecting Interactions Between Bacteria and Antibiotics
Down Relevance of Pharmacokinetics to In-Vitro Models
Down In-Vitro Models of Antibiotic Action
Down Technical Aspects of Various In-Vitro Models
Down In-Vivo Phenomena and In-Vitro Models
Down Applications of In-Vitro Models
Down Clinical Relevance of In-Vitro Models
Down Index


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Front Matter (PDF)

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

Other Departments Back

Deirdre Lewis, David Reeves, Bernd Wiedemann, and Stephen Zinner
Preface
J. Antimicrob. Chemother. 1985 15: iii-iv; doi:10.1093/jac/15.suppl_A.iii [PDF] [Request Permissions]  

In-Vitro Factors Affecting Interactions Between Bacteria and Antibiotics Back

Peter Gilbert
The theory and relevance of continuous culture
J. Antimicrob. Chemother. 1985 15: 1-6; doi:10.1093/jac/15.suppl_A.1 [Abstract] [PDF] [Request Permissions]  

Michael R. W. Brown and Paul Williams
Influence of substrate limitation and growth phase on sensitivity to antimicrobial agents
J. Antimicrob. Chemother. 1985 15: 7-14; doi:10.1093/jac/15.suppl_A.7 [PDF] [Request Permissions]  

Victor Lorian
Low concentrations of antibiotics
J. Antimicrob. Chemother. 1985 15: 15-26; doi:10.1093/jac/15.suppl_A.15 [Abstract] [PDF] [Request Permissions]  

E. Yourassowsky, M. P. van der Linden, M. J. Lismont, F. Crokaert, and Y. Glupczynski
Effect on growth curve patterns of brief exposure of bacteria to different concentrations of β-lactam antibiotics
J. Antimicrob. Chemother. 1985 15: 27-36; doi:10.1093/jac/15.suppl_A.27 [Abstract] [PDF] [Request Permissions]  

Bennett S. Vogelman and William A. Craig
Postantibiotic effects
J. Antimicrob. Chemother. 1985 15: 37-46; doi:10.1093/jac/15.suppl_A.37 [PDF] [Request Permissions]  

Relevance of Pharmacokinetics to In-Vitro Models Back

Jerome J. Schentag, Douglas J. Swanson, and Ian L. Smith
Dual individualization: antibiotic dosage calculation from the integration of in-vitro pharmacodynamics and in-vivo phannacokinetics
J. Antimicrob. Chemother. 1985 15: 47-57; doi:10.1093/jac/15.suppl_A.47 [PDF] [Request Permissions]  

Michael Barza and George Cuchural
General principles of antibiotic tissue penetration
J. Antimicrob. Chemother. 1985 15: 59-75; doi:10.1093/jac/15.suppl_A.59 [Abstract] [PDF] [Request Permissions]  

R. Wise
The relevance of pharmacokinetics to in-vitro models: protein binding—does it matter?
J. Antimicrob. Chemother. 1985 15: 77-83; doi:10.1093/jac/15.suppl_A.77 [PDF] [Request Permissions]  

W. Lintz
Pharmacokinetic considerations for the setting of in-vitro models
J. Antimicrob. Chemother. 1985 15: 85-97; doi:10.1093/jac/15.suppl_A.85 [Abstract] [PDF] [Request Permissions]  

In-Vitro Models of Antibiotic Action Back

Silvio Grasso
Historical review of in-vitro models
J. Antimicrob. Chemother. 1985 15: 99-102; doi:10.1093/jac/15.suppl_A.99 [PDF] [Request Permissions]  

David Greenwood
An in-vitro model simulating the hydrokinetic aspects of the treatment of bacterial cystitis
J. Antimicrob. Chemother. 1985 15: 103-109; doi:10.1093/jac/15.suppl_A.103 [Abstract] [PDF] [Request Permissions]  

John D. Anderson
Relevance of urinary bladder models to clinical problems and to antibiotic evaluation
J. Antimicrob. Chemother. 1985 15: 111-115; doi:10.1093/jac/15.suppl_A.111 [Abstract] [PDF] [Request Permissions]  

Technical Aspects of Various In-Vitro Models Back

W. Tosch and R. Schnell
Possible approaches to the simulation of antibiotic kinetics and the determination of antibacterial activity in vitro
J. Antimicrob. Chemother. 1985 15: 117-120; doi:10.1093/jac/15.suppl_A.117 [Abstract] [PDF] [Request Permissions]  

Ingo Haller
A model to show the role of extracellular β-lactamases in mediating staphylococcal resistance
J. Antimicrob. Chemother. 1985 15: 121-123; doi:10.1093/jac/15.suppl_A.121 [Abstract] [PDF] [Request Permissions]  

Jürg Blaser
In-vitro model for simultaneous simulation of the serum kinetics of two drugs with different half-lives
J. Antimicrob. Chemother. 1985 15: 125-130; doi:10.1093/jac/15.suppl_A.125 [Abstract] [PDF] [Request Permissions]  

Jürg Blaser, Benjamin B. Stone, and Stephen H. Zinner
Two compartment kinetic model with multiple artificial capillary units
J. Antimicrob. Chemother. 1985 15: 131-137; doi:10.1093/jac/15.suppl_A.131 [Abstract] [PDF] [Request Permissions]  

J. Peter Guggenbichler, E. Semenitz, and P. König
Kill kinetics and regrowth pattern of bacteria exposed to antibiotic concentrations simulating those observed in vivo
J. Antimicrob. Chemother. 1985 15: 139-146; doi:10.1093/jac/15.suppl_A.139 [Abstract] [PDF] [Request Permissions]  

Tom Bergan and Ingar B. Carlsen
Effect of antibiotics eliminated by first order kinetics
J. Antimicrob. Chemother. 1985 15: 147-152; doi:10.1093/jac/15.suppl_A.147 [Abstract] [PDF] [Request Permissions]  

Pramod M. Shah
Activity of imipenem in an in-vitro model simulating pharmacokinetic parameters in human blood
J. Antimicrob. Chemother. 1985 15: 153-157; doi:10.1093/jac/15.suppl_A.153 [Abstract] [PDF] [Request Permissions]  

D. S. Reeves
Advantages and disadvantages of an in-vitro model with two compartments connected by a dialyser: results of experiments with ciprofloxacin
J. Antimicrob. Chemother. 1985 15: 159-167; doi:10.1093/jac/15.suppl_A.159 [Abstract] [PDF] [Request Permissions]  

B. Ledergerber, J. Blaser, and R. Lüthy
Computer-controlled in-vitro simulation of multiple dosing regimens
J. Antimicrob. Chemother. 1985 15: 169-173; doi:10.1093/jac/15.suppl_A.169 [Abstract] [PDF] [Request Permissions]  

In-Vivo Phenomena and In-Vitro Models Back

A. Dalhoff
Differences between bacteria grown in vitro and in vivo
J. Antimicrob. Chemother. 1985 15: 175-195; doi:10.1093/jac/15.suppl_A.175 [PDF] [Request Permissions]  

Ingo Haller
Penetration of antibiotics through cell culture monolayers
J. Antimicrob. Chemother. 1985 15: 197-199; doi:10.1093/jac/15.suppl_A.197 [Abstract] [PDF] [Request Permissions]  

A. U. Gerber and C. Feller-Segessenmann
In-vivo assessment of in-vitro killing patterns of Pseudomonas aeruginosa
J. Antimicrob. Chemother. 1985 15: 201-206; doi:10.1093/jac/15.suppl_A.201 [Abstract] [PDF] [Request Permissions]  

Dale N. Gerding, Lance R. Peterson, Julia A. Moody, and Claudine E. Fasching
Mezlocillin, ceftizoxime, and amikacin alone and in combination against six Enterobacteriaceae in a nentropenic site in rabbits
J. Antimicrob. Chemother. 1985 15: 207-219; doi:10.1093/jac/15.suppl_A.207 [Abstract] [PDF] [Request Permissions]  

Applications of In-Vitro Models Back

Stephen H. Zinner, Jürg Blaser, Benjamin B. Stone, and Michael C. Groner
Use of an in-vitro kinetic model to study antibiotic combinations
J. Antimicrob. Chemother. 1985 15: 221-226; doi:10.1093/jac/15.suppl_A.221 [Abstract] [PDF] [Request Permissions]  

A. R. White, D. H. Stokes, B. Slocombe, and R. Sutherland
Bactericidal effects of amoxycillin/clavulanic acid and ticarcillin/clavulanic acid in in-vitro kinetic models
J. Antimicrob. Chemother. 1985 15: 227-232; doi:10.1093/jac/15.suppl_A.227 [Abstract] [PDF] [Request Permissions]  

Heinz Sous and Ingrid Hirsch
Bactericidal activity of phenoxymethylpenicillin in an in-vitro model simulating tissue kinetics
J. Antimicrob. Chemother. 1985 15: 233-239; doi:10.1093/jac/15.suppl_A.233 [Abstract] [PDF] [Request Permissions]  

Astrid H. Seeberg and Bernd Wiedemann
Application of in-vitro models: development of resistance
J. Antimicrob. Chemother. 1985 15: 241-249; doi:10.1093/jac/15.suppl_A.241 [Abstract] [PDF] [Request Permissions]  

Bernd Wiedemann and Wilfried Hüsing
The use of bacteria producing the aminoglycoside inactivating enzyme ANT-(2'') in an in-vitro model
J. Antimicrob. Chemother. 1985 15: 251-256; doi:10.1093/jac/15.suppl_A.251 [Abstract] [PDF] [Request Permissions]  

Catherine A. White and Roger D. Toothaker
Influence of ampicillin elimination half-life on in-vitro bactericidal effect
J. Antimicrob. Chemother. 1985 15: 257-260; doi:10.1093/jac/15.suppl_A.257 [Abstract] [PDF] [Request Permissions]  

Pramod M. Shah
Simultaneous simulation of two different concentration time curves in vitro
J. Antimicrob. Chemother. 1985 15: 261-264; doi:10.1093/jac/15.suppl_A.261 [Abstract] [PDF] [Request Permissions]  

Rainer Haag
Post-MIC effect of fosfomycin on Pseudomonas aeruginosa in vitro and in experimentally infected mice
J. Antimicrob. Chemother. 1985 15: 265-271; doi:10.1093/jac/15.suppl_A.265 [Abstract] [PDF] [Request Permissions]  

O. Zak, W. Tosch, and M. A. Sande
Correlation of antibacterial activities of antibiotics in vitro and in animal models of infection
J. Antimicrob. Chemother. 1985 15: 273-282; doi:10.1093/jac/15.suppl_A.273 [Abstract] [PDF] [Request Permissions]  

A. Dalhoff and G. Stübner
Comparative analysis of the antimicrobial action of polymorphonuclear leucocytes in vitro, ex vivo and in vivo
J. Antimicrob. Chemother. 1985 15: 283-291; doi:10.1093/jac/15.suppl_A.283 [Abstract] [PDF] [Request Permissions]  

Clinical Relevance of In-Vitro Models Back

Thomas A. Drake, W. Micheal Scheld, and Merle A. Sande
Effects of sub-bactericidal concentrations of antibiotics in experimental models of endocarditis
J. Antimicrob. Chemother. 1985 15: 293-296; doi:10.1093/jac/15.suppl_A.293 [Abstract] [PDF] [Request Permissions]  

P. Francioli and M. P. Glauser
Successful prophylaxis of experimental streptococcal endocarditis with single doses of sublethal concentrations of penicillin
J. Antimicrob. Chemother. 1985 15: 297-302; doi:10.1093/jac/15.suppl_A.297 [Abstract] [PDF] [Request Permissions]  

W. Michael Scheld, Martin G. Tauber, Otokar Zak, and Merle A. Sande
The influence of dosing schedules and cerebrospinal fluid bactericidal activity on the therapy of bacterial meningitis
J. Antimicrob. Chemother. 1985 15: 303-312; doi:10.1093/jac/15.suppl_A.303 [Abstract] [PDF] [Request Permissions]  

Joyce J. Mordenti, Richard Quintiliani, and Charles H. Nightingale
Combination antibiotic therapy: comparison of constant infusion and intermittent bolus dosing in an experimental animal model
J. Antimicrob. Chemother. 1985 15: 313-322; doi:10.1093/jac/15.suppl_A.313 [Abstract] [PDF] [Request Permissions]  

Index Back

Index
J. Antimicrob. Chemother. 1985 15: 323-326; doi:10.1093/jac/15.suppl_A.323 [PDF] [Request Permissions]  

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.