Skip Navigation



JAC Advance Access published online on March 12, 2008
Journal of Antimicrobial Chemotherapy, doi:10.1093/jac/dkn093
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
61/6/1244    most recent
dkn093v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Lavilla, S.
Right arrow Articles by Prats, G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Lavilla, S.
Right arrow Articles by Prats, G.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author 2008. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Original research

Dissemination of extended-spectrum β-lactamase-producing bacteria: the food-borne outbreak lesson

S. Lavilla1,2, J. J. González-López1,2, E. Miró3, A. Domínguez4, M. Llagostera2, R. M. Bartolomé1,2, B. Mirelis2,3, F. Navarro2,3 and G. Prats1,2,*

1 Servei de Microbiologia, Hospital Vall d'Hebron, Barcelona, Spain; 2 Departament de Genètica i de Microbiologia de la Universitat Autònoma de Barcelona, Cerdanyola del Vallès, Spain; 3 Servei de Microbiologia, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain; 4 Departament de Salut Pública, Universitat de Barcelona, Barcelona, Spain

Received 14 September 2007; returned 2 December 2007; revised 25 January 2008; accepted 16 February 2008

* Correspondence address. Servei de Microbiologia, Hospital Vall d'Hebron, P. Vall d'Hebron, 119-129, 08035 Barcelona, Spain. Tel: +34-93-2746817; Fax: +34-93-2746801; E-mail: gprats{at}vhebron.net

Objectives: Commensal and opportunistic bacteria producing extended-spectrum β-lactamases (ESBL-PB) have undergone a broad and rapid spread within the general population; however, the routes of dissemination have not been totally elucidated. The aim of this study was to determine whether individuals involved in an outbreak of acute gastroenteritis, in addition to the enteropathogenic microorganism, share an ESBL-PB as indirect demonstration of its transmission from a common food source.

Methods: From 2003 to 2004 in Barcelona, Spain, stool samples from 905 people involved in 132 acute gastroenteritis outbreaks and 226 food handlers related to the outbreaks were investigated.

Results: In 31 outbreaks, 58 diners carrying one or more ESBL-PB were detected. In 10 outbreaks, two or more diners shared the same ESBL-PB, and in four of them, the strain was shared with the food handlers.

Conclusions: This study provides circumstantial evidence that foods can be a transmission vector for ESBL-PB, probably from two reservoirs, food animals and food handlers.

Key Words: food handling , epidemiology , reservoir


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 J Antimicrob ChemotherHome page
A. Coelho, B. Mirelis, C. Alonso-Tarres, M. N. Larrosa, E. Miro, R. C. Abad, R. M. Bartolome, M. Castaner, G. Prats, J. R. Johnson, et al.
Detection of three stable genetic clones of CTX-M-15-producing Klebsiella pneumoniae in the Barcelona metropolitan area, Spain
J. Antimicrob. Chemother., October 1, 2009; 64(4): 862 - 864.
[Full Text] [PDF]

Home page
 J. Clin. Microbiol.Home page
A. Valverde, F. Grill, T. M. Coque, V. Pintado, F. Baquero, R. Canton, and J. Cobo
High Rate of Intestinal Colonization with Extended-Spectrum-{beta}-Lactamase-Producing Organisms in Household Contacts of Infected Community Patients
J. Clin. Microbiol., August 1, 2008; 46(8): 2796 - 2799.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.