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JAC Advance Access published online on February 14, 2008
Journal of Antimicrobial Chemotherapy, doi:10.1093/jac/dkn039
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© The Author 2008. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Leading article

Antibiotic policies to control hospital-acquired infection

I. M. Gould*

Department of Medical Microbiology, Aberdeen Royal Infirmary, Foresterhill, Aberdeen AB25 2ZN, Scotland, UK

* Tel: +44-1224-554954; Fax: +44-1224-550632; E-mail: i.m.gould{at}abdn.ac.uk

Antibiotic use is widely accepted as being responsible for the selection and maintenance of antibiotic resistance. It is less obvious, however, that it is also responsible for increasing transmissibility and pathogenicity of many multiresistant bacteria and may actually be increasing the number of hospital-acquired infections (HAIs). Antibiotic stewardship should be given much more emphasis in the fight against HAI.

Key Words: MRSA , stewardship , Clostridium difficile , randomized controlled trials


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