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JAC Advance Access published online on April 10, 2006
Journal of Antimicrobial Chemotherapy, doi:10.1093/jac/dkl113
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© The Author 2006. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Review

Key questions in antiretroviral therapy: Italian Consensus Workshop (2005)

G. Carosi 1, C. Torti 1 *, M. Andreoni 2, G. Angarano 3, A. Antinori 4, S. Bonora 5, M. Borderi 6, A. Castagna 7, F. Castelli 1, R. Cauda 8, F. Chiodo 6, A. D'arminio-Monforte 9, A. De Luca 8, G. Di Perri 5, F. Dianzani 10, G. Filice 11, M. Galli 12, A. Lazzarin 7, F. Maggiolo 13, R. Maserati 11, F. Mazzotta 14, M. Moroni 12, C. F. Perno 2, V. Vullo 4, and on behalf of the Members of the Italian HIV Guidelines Working Group {dagger}

1 University of Brescia, Brescia, Italy
2 ‘Tor Vergata’ University, Rome, Italy
3 University of Foggia, Foggia, Italy
4 INMI, Rome, Italy
5 University of Turin, Turin, Italy
6 University of Bologna, Bologna, Italy
7 Università Vita-Salute, S. Raffaele, Milan, Italy
8 Catholic University, Rome, Italy
9 Ospedale ‘S. Paolo’, Milan, Italy
10 ‘Campus Biomedico’, Rome, Italy
11 University of Pavia, IRCCS Policlinico S. Matteo, Pavia, Italy
12 Ospedale ‘L. Sacco’, Milan, Italy
13 Ospedali Riuniti, Bergamo, Italy
14 Ospedale ‘S. Maria Annunziata’, Florence, Italy

* To whom correspondence should be addressed.
C. Torti, E-mail: torti.carlo{at}libero.it


  Abstract

A panel of leading Italian specialists in infectious diseases, virologists and immunologists met in Rome in 2005 to review critical data and discuss recommendations for each of the key questions in antiretroviral therapy today: When to start treatment? How to start? When to switch? What to switch to? Whether to stop or not to stop treatment, and how? The method of a nominal group meeting was used and recommendations were graded for their strength and quality using a system based on the one adopted by the Infectious Diseases Society of America. Main conclusions are summarized and critically discussed in this consensus statement, as well as some of the most recent data supporting these recommendations are provided.

Keywords: HIV; HAART; guidelines.
{dagger}Members are listed in the Acknowledgements section.
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