JAC Advance Access published online on March 16, 2005
Journal of Antimicrobial Chemotherapy, doi:10.1093/jac/dki079
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1 Department of Medical Microbiology and Infectious Diseases, Canisius Wilhelmina Hospital, Weg door Jonkerbos 100, 6532 sz Nijmegen, The Netherlands
* To whom correspondence should be addressed. Interest in the relationships between the pharmacokinetics (PK) and pharmacodynamics (PD) of antimicrobial agents has increased over recent years. Since the appearance 2 years ago of our first article describing terminology in PK/PD, the field has continued to expand rapidly, urgently requiring an update. This paper describes in a uniform manner the use of PK/PD expressions for antimicrobial agents, and their units.
Leading article
Standardization of pharmacokinetic/pharmacodynamic (PK/PD) terminology for anti-infective drugs: an update
2 Diversa Corp., San Diego, CA, USA
3 Department of Infectious Diseases, Uppsala University Hospital, Uppsala, Sweden
4 Department of Pharmaceutics, University of Florida, Gainesville, FL, USA
5 Ordway Research Institute, Albany, New York, NY, USA
Johan W. Mouton, E-mail: Mouton{at}cwz.nl
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