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JAC Advance Access published online on November 12, 2003
Journal of Antimicrobial Chemotherapy, doi:10.1093/jac/dkg484
© 2003 by The British Society for Antimicrobial Chemotherapy
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© 2003 Published by Oxford University Press

Brief report

Antibiotic susceptibilities of 94 isolates of Yersinia pestis to 24 antimicrobial agents

Eric Hernandez 1 *, Monique Girardet 1 , Francoise Ramisse 2 , Dominique Vidal 3 , and Jean-Didier Cavallo 1

1 Hôpital d’iInstruction des armées Bégin, Biologie médicale, Saint-mandé;
2 Centre d’études du Bouchet, Laboratoire de microbiologie, Vert-le-petit;
3 Centre de recherches du service de santé des armées, Laboratoire de microbiologie, La tronche, France

* Corresponding author. E-mail: hnz.eric{at}freesurf.fr.

Received 10 April 2003 ; revised 13 August 2003 ; accepted 25 September 2003

Abstract

Ninety-four isolates of Yersinia pestis collected by the French army between 1964 and 1988 were evaluated for their susceptibilities to 24 antibiotics by the agar dilution method. All the isolates were susceptible to {beta}-lactam antibiotics including imipenem, to fluoroquinolones, aminoglycosides and to doxycycline. The most active compounds were fluoroquinolone antibiotics, third-generation cephalosporins and aminoglycosides.

Keywords: Y. pestis, antibiotic susceptibility, plague
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