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JAC Advance Access published online on November 28, 2002
Journal of Antimicrobial Chemotherapy, doi:10.1093/jac/dkg034
© 2002 by The British Society for Antimicrobial Chemotherapy
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© 2002 The British Society for Antimicrobial Chemotherapy

In Brief

Antibiotic resistance of Neisseria gonorrhoeae in Spain: trends over the last two decades

L. Arreaza 1, C. Salcedo 1, B. Alcalá 1, S. Berrón 1, E. Martín 1, J. A. Vázquez 1*

1 Laboratorio de Referencia de Neisserias, Servicio de Bacteriología, Centro Nacional de Microbiología, Instituto de Salud Carlos III, 28220 Majadahonda, Madrid, Spain

* Corresponding author. E-mail: jvazquez{at}isciii.es.

Received 12 July 2002 ; revised 28 August 2002 ; accepted 10 October 2002

Abstract

In vitro activities of six antimicrobial agents against 2966 strains of Neisseria gonorrhoeae, isolated in Spain between 1983 and 2001, were determined. The percentages of intermediately susceptible and resistant isolates to penicillin (MIC >= 0.12 mg/L) and tetracycline (MIC >= 0.5 mg/L) were very high over the period of study. Strains intermediately susceptible to cefoxitin were identified at a variable percentage during the study. All N. gonorrhoeae isolates were susceptible to spectinomycin and ceftriaxone. Recently, resistance to ciprofloxacin has emerged.

Keywords: gonococci, antibiotic susceptibility
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