JAC Advance Access published online on November 1, 2002
Journal of Antimicrobial Chemotherapy, doi:10.1093/jac/dkf252
© 2002 by The British Society for Antimicrobial Chemotherapy
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Report
1 Sera and Vaccines Central
Research Laboratory, ul. Che
* Corresponding author. E-mail: waleria{at}urania.il.waw.pl.
Received 25 March 2002
; revised 30 August 2002
; accepted 16 September 2002
The first heterogeneously vancomycin-intermediate Staphylococcus aureus (hVISA) isolates to be identified
in Poland were characterized. They were recovered in two Warsaw
hospitals and, although in one of these the identification coincided
with unsuccessful glycopeptide therapy, the selection conditions
and clinical significance of the organisms remain unclear. Molecular typing
revealed that the isolates were closely related and belonged to
an international methicillin-resistant S. aureus (MRSA)
clone known as ‘Iberian'. The analysis of epidemiologically
related MRSA isolates and some archival Polish MRSA isolates of
the same clone indicated that the hVISA phenotype has been present
in the MRSA populations of some hospitals in Poland since at least
1998.
The first Staphylococcus aureus isolates
with reduced susceptibility to vancomycin in Poland
-Russjan 1,
owniak-Pracka 2,
bieta Hagmajer 2,
mska 30/34, 00-725 Warsaw
2 The Maria Sk
odowska-Curie
Memorial Centre and Institute of Oncology, ul. Roentgena 5, 02-185
Warsaw, Poland
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