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JAC Advance Access published online on September 6, 2002
Journal of Antimicrobial Chemotherapy, doi:10.1093/jac/dkf169
© 2002 by The British Society for Antimicrobial Chemotherapy
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© 2002 The British Society for Antimicrobial Chemotherapy

In Brief

Prevalence of erm(A) and mef(B) erythromycin resistance determinants in isolates of Streptococcus pneumoniae from New Zealand

David C. Bean 1* John D. Klena 1

1 Plant and Microbial Science Department, University of Canterbury, Christchurch, New Zealand

* Corresponding author. E-mail: d.bean{at}botn.canterbury.ac.nz.

Received 15 January 2002 ; revised 18 June 2002 ; accepted 8 July 2002

Abstract

One hundred and twenty-four erythromycin-resistant pneumococcal isolates were examined for the presence of macrolide resistance genes. The erm(B) gene was detected in 118 (95.2%) isolates and the mef(A) gene in 83 (66.9%) isolates. Both the mef(A) and erm(B) genes were detected in 77 (62.1%) isolates. DNA macrorestriction analysis of these isolates identified them as belonging to a single multi-resistant clone.


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