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Journal of Antimicrobial Chemotherapy (1981) 8, 283-290
© 1981 The British Society for Antimicrobial Chemotherapy

research-article

Single dose of tinidazole in prophylaxis of infections following vaginal surgery

M. Karhunen, O. Koskela and K. Hällström

Department of Obstetrics and Gynaecology, Etelä-Saimaa Central Hospital and The District Public Health Laboratory Lappeenranta, Finland

accepted 20 May 1981

A single dose of 2 g of tinidazole was preoperatively given to 51 patients who underwent vaginal surgery; 60 patients served as controls. The overall infection rate of the operation site was 5.9% (3/51) in the tinidazole group and 25.0% (15/60) in the control group. The difference was significant.


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