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JAC Advance Access originally published online on January 21, 2009
Journal of Antimicrobial Chemotherapy 2009 63(3):615-616; doi:10.1093/jac/dkn518
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© The Author 2009. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Research letters

No evidence for cross-contamination of dried blood spots excised using an office hole-punch for HIV-1 drug resistance genotyping

Andrew J. Buckton1,*, Damayanti P. Prabhu1, Patricia A. Cane1 and Deenan Pillay1,2

1 Virus Reference Department, Centre for Infections, Health Protection Agency, London, UK 2 Division of Infection and Immunity, University College, London, UK

* Corresponding author. Tel: +44-20-8327-6470; Fax: +44-20-8200-1569; E-mail: andrew.buckton@hpa.org.uk

Keywords: filter paper , antiretrovirals , scale-up

The first 10% of the full text of this article appears below.

Sir,

In a recent report, we described a laboratory procedure to perform HIV-1 genotypic drug resistance testing from dried blood spots (DBS).1 The methodology as a whole was subjected to rigorous validation. However, it has since been pointed out to us that we had not demonstrated that the process for cleaning the hole-punch used to excise DBS from filter paper . . . [Full Text of this Article]


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[Abstract] [Full Text] [PDF]