JAC Advance Access originally published online on December 4, 2008
Journal of Antimicrobial Chemotherapy 2009 63(2):406-408; doi:10.1093/jac/dkn492
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© The Author 2008. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org
Research letters |
Detection of qnr genes in Salmonella isolated from humans in Denmark
Statens Serum Institut, Copenhagen, Denmark
* Corresponding author. Department of Bacteriology, Mycology and Parasitology, Statens Serum Institut, Artillerivej 5, 2300 Copenhagen, Denmark. Tel: +45-32683644; Fax: +45-32688238; E-mail: emn@ssi.dk
Keywords: ciprofloxacin , gene transfer , quinolones
| The first 10% of the full text of this article appears below. |
Sir,
Since plasmid-mediated quinolone resistance was originally reported in a Klebsiella pneumoniae in 1998, the plasmid-borne qnr genes, qnrA, B and S, and their variants have been found in several enterobacterial species from several countries.1 This includes Denmark, where Salmonella Corvallis isolated from human infections were found to be positive for the plasmid-borne qnrS1.2
From September 2002 through December 2007, 6525 Salmonella isolates from human infections were tested for their antimicrobial susceptibility by broth microdilution (Sensititre; Trek Diagnostic Systems Ltd, East Grinstead, UK). The isolates that were tested included all incoming Salmonella Typhimurium, 50% of Salmonella Enteritidis, the 10 most
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