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JAC Advance Access originally published online on April 12, 2008
Journal of Antimicrobial Chemotherapy 2008 62(2):424-425; doi:10.1093/jac/dkn159
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© The Author 2008. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Research letters

Successful oral therapy switch to trimethoprim/sulfamethoxazole in the case of an Enterococcus faecium liver abscess

Gabriel-Adrian Popescu1,2,*, Liana Gavriliu1,2, Cristina Popescu1,2, Mona Popoiu3 and Georgeta Popa4

1 Infectious Diseases Department, ‘Matei Bals’ Infectious Diseases Institute, Bucharest, Romania 2 ‘Carol Davila’ University of Medicine, Bucharest, Romania 3 Bacteriology Department, ‘Matei Bals’ Infectious Diseases Institute, Bucharest, Romania 4 Imaging/Radiology Department, ‘Matei Bals’ Infectious Diseases Institute, Bucharest, Romania

* Corresponding author. Tel: +40-213186100; Fax: +40-213186090; E-mail: gabrielp9@yahoo.com

Keywords: intravenous-to-oral switch therapy , intraabdominal abscess , enterococcal infection

The first 10% of the full text of this article appears below.

Sir,

The appropriate treatment for liver abscess consists of surgical drainage and antimicrobial therapy, according to the isolated bacteria. Mortality is still high: 8% to 12.8% for a single abscess and 11% to 21% for multiple abscesses,1–3 despite the introduction of guided percutaneous drainage of abscesses and new antibiotics. Enterococcus faecium has been implicated in liver abscess, and its antimicrobial resistance limits therapeutic options. We present a case of a patient with a liver abscess due to E. . . . [Full Text of this Article]


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