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JAC Advance Access originally published online on February 13, 2008
Journal of Antimicrobial Chemotherapy 2008 61(5):1169-1171; doi:10.1093/jac/dkn055
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© The Author 2008. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Original research

Increased antimicrobial consumption following reimbursement reform in Turkey

Oguz Karabay1,* and Salih Hosoglu2

1 Department of Clinical Microbiology and Infectious Diseases, Abant Izzet Baysal University Hospital, Bolu, Turkey 2 Department of Clinical Microbiology and Infectious Diseases, Dicle University Hospital, Diyarbakir, Turkey

Received 9 August 2007; returned 28 October 2007; revised 22 January 2008; accepted 23 January 2008


* Corresponding author. Tel: +90-3742534656; Fax: +90-3742534615; E-mail: drkarabay{at}yahoo.com

Objectives: This study examined antibiotic utilization patterns in Turkey between 2001 and 2006.

Methods: A comprehensive collection and analysis of Turkish antibiotic data from 2001 to 2006 was conducted. The anatomical therapeutic chemical (ATC) classification and the defined daily dose (DDD) methodology were used to calculate antibiotic consumption. Data were presented as DDD/1000 inhabitant-days, and the relation between antimicrobial consumption and governmental reimbursement policy was evaluated.

Results: Total utilization of antibiotics increased from 14.62 to 31.36 DDD/1000 inhabitant-days between 2001 and 2006. The largest increase took place after the implementation of social insurance reform (SIR) in 2005, as evidenced by the DDD ratio increasing 1.87-fold after SIR went into effect. The largest increase occurred in the prescription of penicillins, from 7.13 in 2001 to 14.09 in 2006.

Conclusions: In Turkey, antibiotic consumption increased markedly in recent years, in a close relationship, to a new reimbursement policy following the implementation of the SIR, which facilitated the prescription and consumption of drugs compared with the earlier SIR conditions.

Keywords: antibiotic policy , antibacterial drug screening policy , antimicrobial agents , antimicrobial resistance surveillance


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