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JAC Advance Access originally published online on January 27, 2008
Journal of Antimicrobial Chemotherapy 2008 61(4):959-960; doi:10.1093/jac/dkn021
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© The Author 2008. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Research letters

ccrB typing tool: an online resource for staphylococci ccrB sequence typing

Duarte C. Oliveira1,*, Mauro Santos2, Catarina Milheiriço1, João A. Carriço2, Susana Vinga2, Arlindo L. Oliveira2 and Hermínia de Lencastre1,3

1 Laboratory of Molecular Genetics, Instituto de Tecnologia Química e Biológica (ITQB), Universidade Nova de Lisboa, Rua da Quinta Grande, 6, 2780-156 Oeiras, Portugal 2 INESC-ID, Instituto de Engenharia de Sistemas e Computadores: Investigação e Desenvolvimento, Lisboa, Portugal 3 Laboratory of Microbiology, The Rockefeller University, New York, NY 10065, USA

* Corresponding author. Tel: +351-21-446-9862; Fax: +351-21-442-8766; E-mail: dco@itqb.unl.pt

Keywords: ccr typing , SCCmec typing , staphylococci , MRSA , CoNS

The first 10% of the full text of this article appears below.

Sir,

In 2006, we published a manuscript in this journal describing the allelic variation in the ccrAB locus in a representative collection of methicillin-resistant Staphylococcus aureus (MRSA) based on DNA sequencing of internal fragments of both genes.1 This work confirmed the very close relationships among ccrAB alleles associated with SCCmec types I–IV and VI, which was found to be independent of the MRSA lineage, geographic origin or isolation period. Moreover, particularly for the ccrB gene, SCCmec types II and IV, both defined by ccrAB allotype 2, could be discriminated. This . . . [Full Text of this Article]


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