JAC Advance Access originally published online on January 25, 2008
Journal of Antimicrobial Chemotherapy 2008 61(3):753-754; doi:10.1093/jac/dkm540
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© The Author 2008. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org
Research letters |
Red bayberry extract inhibits growth and virulence gene expression of the human pathogen Vibrio cholerae
1 The State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, China 2 MOA Key Lab of Microbiological Engineering of Agricultural Environment, Nanjing Agricultural University, Nanjing, China 3 Department of Microbiology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
* Correspondence address. Department of Microbiology, MOA Key Lab of MEAE, Nanjing Agricultural University, Nanjing, China. Tel/Fax: +86-1186-25-8436645; E-mail: jun_zhu@njau.edu.cn
Keywords: cholera , Myrica rubra , growth inhibition
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Sir,
Today, when most clinically relevant bacteria are displaying increasing antibiotic resistance, discovery of novel and cost-efficient antimicrobial compounds is increasingly critical. Vibrio cholerae is a Gram-negative bacterium that is the causative agent for the severe diarrhoeal disease cholera, which still remains a global killer mainly in the developing countries.1 In addition to causing significant mortality, V. cholerae also causes high rates of morbidity, which imposes a severe social and economic burden on affected communities that are often already lacking in medical and economic resources.
Red bayberry (
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