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JAC Advance Access originally published online on November 22, 2007
Journal of Antimicrobial Chemotherapy 2008 61(2):464; doi:10.1093/jac/dkm450
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© The Author 2007. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Letters to the Editor

Acinetobacter spp. and time–kill studies

Horacio A. Lopardo*

Servicio de Microbiología, Hospital de Pediatría ‘Prof Dr Juan P Garrahan’, Buenos Aires, Argentina

* Corresponding author. Tel: +54-11-4308-4300; Fax: +54-11-4308-5325; E-mail: hlopardo@garrahan.gov.ar

Keywords: killing kinetics , antimicrobial interactions , synergism

The first 10% of the full text of this article appears below.

Sir,

Multidrug-resistant isolates of Acinetobacter spp. have become a worldwide threat for hospitalized patients in recent years. Two papers recently published in JAC referred to in vitro tests of combinations destined to kill carbapenem-resistant Acinetobacter isolates.1,2 The respective authors found effective combinations that may be useful for the treatment of severe infections due to such isolates. However, in my view there are technical considerations regarding the time–kill studies . . . [Full Text of this Article]


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