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JAC Advance Access originally published online on October 26, 2007
Journal of Antimicrobial Chemotherapy 2008 61(1):224-225; doi:10.1093/jac/dkm405
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© The Author 2008. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Research letters

Elimination of daptomycin in a patient with acute renal failure undergoing extended daily dialysis

Olaf Burkhardt1, Christian Joukhadar2, Friederike Traunmüller2, Johannes Hadem3, Tobias Welte1 and Jan T. Kielstein4,*

1 Department of Pulmonary Medicine, Medical School Hannover, Hannover, Germany 2 J&P Medical Research Ltd, Vienna, Austria 3 Department of Gastroenterology, Hepatology and Endocrinology, Medical School Hannover, Hannover, Germany 4 Department of Nephrology, Medical School Hannover, Hannover, Germany


* Corresponding author. Tel: +49-511-532-6319; Fax: +49-511-532-4005; E-mail: Kielstein@yahoo.com

Keywords: Gram-positive infections , endocarditis , renal replacement therapy

The first 10% of the full text of this article appears below.

Sir,Daptomycin is a new intravenous cyclic lipopeptide antibiotic, representing a new class of antibiotics with a spectrum of activity similar to vancomycin. It is licensed in the USA and Europe for the treatment of complicated skin and soft tissue infections caused by Gram-positive organisms including both susceptible and resistant strains of Staphylococcus aureus at a dose of 4 mg/kg once daily.1 Additionally it has been licensed in both the USA and Europe for the treatment of various infections due to susceptible organisms, including serious and life-threatening Gram-positive infections, vancomycin-resistant enterococcal infections and . . . [Full Text of this Article]


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