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JAC Advance Access originally published online on November 16, 2007
Journal of Antimicrobial Chemotherapy 2008 61(1):219-220; doi:10.1093/jac/dkm444
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© The Author 2007. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Research letters

Detection of blaVIM-2 carbapenemase in Pseudomonas aeruginosa in Ireland

F. Walsh* and T. R. Rogers

Department of Clinical Microbiology, Trinity College Dublin, St James's Hospital, Dublin 8, Ireland

* Corresponding author. Tel: +353-1-896-3620; E-mail: walshf1@tcd.ie

Keywords: P. aeruginosa , metallo-β-lactamases , MBLs

The first 10% of the full text of this article appears below.

Sir,

Pseudomonas aeruginosa is one of the most frequently isolated Gram-negative pathogens associated with hospital-acquired infections. The carbapenems, imipenem and meropenem, have a broad spectrum of activity and are considered the agents of choice for the treatment of P. aeruginosa infections. However, metallo-β-lactamases (MBLs), which readily hydrolyse most β-lactams, including carbapenems, are increasingly being identified among P. aeruginosa clinical isolates. The VIM-type MBLs have been widespread in Asia, Southern Europe and . . . [Full Text of this Article]


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