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JAC Advance Access originally published online on July 10, 2007
Journal of Antimicrobial Chemotherapy 2007 60(3):703-704; doi:10.1093/jac/dkm267
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© The Author 2007. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Correspondence

Detection of OXA-2 group extended-spectrum-ß-lactamase-producing clinical isolates of Escherichia coli from India

Amitabha Bhattacharjee, Malay Ranjan Sen*, Shampa Anupurba, Pradyot Prakash and Gopal Nath

Department of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221005, India

* Corresponding author. Tel: +91-9415820675; E-mail: mr_senbhu@yahoo.com

Keywords: E. coli , ESBLs , OXA-type

The first 10% of the full text of this article appears below.

Sir,

Since the first report of an extended-spectrum ß-lactamase (ESBL) in the early 1980s, several classes of ESBLs have been described, along with their respective genes in the chromosomal/plasmid DNA, among clinical bacterial isolates, particularly, Escherichia coli and Klebsiella species. OXA-type ß-lactamases, belonging to molecular class D and functional group 2d, are characterized by their high hydrolytic activity against oxacillin and cloxacillin and are poorly inhibited by clavulanic acid. Extension of the hydrolytic spectrum of oxacillinase to . . . [Full Text of this Article]

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