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JAC Advance Access originally published online on April 17, 2007
Journal of Antimicrobial Chemotherapy 2007 59(6):1280-1281; doi:10.1093/jac/dkm092
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© The Author 2007. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Correspondence

Low-level exposure of MRSA to octenidine dihydrochloride does not select for resistance

Z. Al-Doori1,*, P. Goroncy-Bermes2, C. G. Gemmell1,3 and D. Morrison1

1 Scottish MRSA Reference Laboratory, Stobhill Hospital, Glasgow, UK 2 Schuelke and Mayr GmbH, Germany 3 Glasgow University Division of Immunology, Infection and Inflammation, Glasgow, Scotland, UK

* Corresponding author. Tel: +44-1236734427; Fax: +44-1236730545; E-mail: zainab.aldoori@btopenworld.com

Keywords: antiseptics , mutagenesis , biocides

The first 10% of the full text of this article appears below.

Sir,

Methicillin-resistant Staphylococcus aureus (MRSA) is prevalent in hospitals and contributes significantly to morbidity and mortality in infected patients. Antiseptics are an important element in the prevention and treatment of MRSA infections.

Octenidine dihydrochloride {N, N'-(1,10 decanediyldi-1[4H]-pyridinyl-4-ylidene) bis-(1-octanamine)} is a new cationic antiseptic that belongs to the bispyridine class of chemicals. It has activity against Gram-positive and Gram-negative bacteria.1 It . . . [Full Text of this Article]

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Effect of Octenidine Hydrochloride on Planktonic Cells and Biofilms of Listeria monocytogenes
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[Abstract] [Full Text] [PDF]