JAC Advance Access originally published online on April 16, 2007
Journal of Antimicrobial Chemotherapy 2007 59(5):1039-1040; doi:10.1093/jac/dkm046
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© The Author 2007. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org
Correspondence |
Comparison of Etest with agar dilution for testing the susceptibility of Pseudomonas aeruginosa and other multidrug-resistant bacteria to colistin
Hospital Saint-Joseph, 185 rue Raymond Losserand, 75014 Paris, France
* Corresponding author. Tel: +33-144123650; Fax: +33-144123685; E-mail: fgoldstein@hopital-saint-joseph.org
Keywords: P. aeruginosa , susceptibility testing , resistance
| The first 10% of the full text of this article appears below. |
Sir,
Colistin, introduced for clinical use > 45 years ago, has not been widely prescribed because of an alleged poor activity and high toxicity.1
The increasing prevalence of multidrug-resistant Gram-negative bacteria has stimulated the potential indication of colistin in life-threatening infections.
In recent studies, colistin has been considered as an effective and less toxic compound than in older studies, under the conditions of modern patient care and drug monitoring.1,2 Colistin is used parenterally as sodium colistin methanesulfonate,
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