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JAC Advance Access originally published online on July 24, 2006
Journal of Antimicrobial Chemotherapy 2006 58(3):705-706; doi:10.1093/jac/dkl285
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© The Author 2006. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Correspondence

Dissemination of nim-class genes, encoding nitroimidazole resistance, among different species of Gram-negative anaerobic bacteria isolated in Athens, Greece

Anastasia Katsandri1,2, Athina Avlamis1, Angeliki Pantazatou1, Dimitra P. Houhoula2 and Joseph Papaparaskevas2,*

1 Department of Microbiology, Laikon General Hospital Athens, Greece 2 Department of Microbiology, Medical School, National and Kapodistrian University of Athens Greece

*Corresponding author. Dr Joseph Papaparaskevas, Lecturer, Department of Microbiology, Medical School, National and Kapodistrian University of Athens, Mikras Asias 75, 11527, Athens, Greece. Tel: +30-210-7462142; Fax: +30-210-7462143; Email: ipapapar@med.uoa.gr

Keywords: Resistance mechanisms , anaerobes , resistance epidemiology

The first 10% of the full text of this article appears below.

Sir,

Metronidazole remains the cornerstone for treatment of anaerobic infections1 and, despite its widespread use, isolation of resistant strains is uncommon.1,2 Nevertheless, enzymatic modification mediated by nim-class genes is a well-characterized resistance mechanism, and a total of seven different nim genes have been described.3,4

The aim of the present study was to investigate the prevalence and to identify the nim gene types among Gram-negative anaerobic clinical strains belonging to different species, isolated from hospitalized patients, in Athens, Greece.

Since 2003, Gram-negative anaerobic . . . [Full Text of this Article]

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