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JAC Advance Access originally published online on December 30, 2005
Journal of Antimicrobial Chemotherapy 2006 57(2):366; doi:10.1093/jac/dki466
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© The Author 2005. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Correspondence

Invasive Haemophilus influenzae isolates with decreased levofloxacin susceptibility in Hong Kong

P. L. Ho1,*, Gannon C. Mak1, Cindy W. S. Tse2, K. H. Chow1 and Chris H. Y. Cheung3

1 Centre of Infection and Department of Microbiology, The University of Hong Kong, Hong Kong SAR, China; 2 Department of Clinical Pathology, Princess Margaret Hospital, Hong Kong SAR, China;3 Department of Clinical Pathology, Pamela Youde Hospital, Hong Kong SAR, China

* Corresponding author. Division of Infectious Diseases, Department of Microbiology, The University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Pokfulam, Hong Kong SAR, China. Tel: +852-2855-4897; Fax: +852-2855-1241; E-mail: plho@hkucc.hku.hk

Keywords: bacteraemia , fluoroquinolones , antimicrobial resistance , H. influenzae , molecular diagnostic techniques

The first 10% of the full text of this article appears below.

Sir,

Although Haemophilus influenzae with phenotypic resistance to fluoroquinolones remains rare, recent studies suggested that decreased susceptibility due to first-step mutations in gyrA or parC may be more common.1,2 First-step mutants with reduced susceptibility generally remain undetected when fluoroquinolone susceptibility tests are interpreted using current breakpoints. However, it is important . . . [Full Text of this Article]

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