JAC Advance Access originally published online on September 23, 2005
Journal of Antimicrobial Chemotherapy 2005 56(5):986-988; doi:10.1093/jac/dki349
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© The Author 2005. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org
Correspondence |
Spread of multiresistance and extended-spectrum ß-lactamases amongst urinary Escherichia coli in Oxford, UK
1 Nuffield Department of Clinical Laboratory Sciences, University of Oxford, Oxford, UK; 2 Department of Microbiology, John Radcliffe Hospital, Headley Way, Oxford OX3 9DU, UK
* Corresponding author. Tel: +44-1865-221226; Fax: +44-1865-764192; E-mail: david.wyllie@ndcls.ox.ac.uk
Keywords: E. coli , epidemiology , ESBLs , ciprofloxacin
| The first 10% of the full text of this article appears below. |
Sir,
Escherichia coli is the commonest trigger for urinary tract infection, and is an important cause of bacteraemia. In the UK, two worrying trends in E. coli antimicrobial resistance have been described recently: the increase in ciprofloxacin resistance in bloodstream isolates,1 and the isolation in multiple areas of the UK of strains of E. coli expressing a recently emerged strain of ß-lactamase, designated CTX-M.2 The emergence of CTX-M enzymes, which can be missed by the laboratory tests formerly
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