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JAC Advance Access originally published online on August 8, 2005
Journal of Antimicrobial Chemotherapy 2005 56(3):601-602; doi:10.1093/jac/dki280
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© The Author 2005. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oupjournals.org

Correspondence

Bacterial prostatitis due to Pseudomonas aeruginosa harbouring the blaVIM-2 metallo-ß-lactamase gene from Saudi Arabia

François Guerin1, Corneliu Henegar2, Gabriella Spiridon2, Odile Launay2, Dominique Salmon-Ceron2 and Claire Poyart1,*

1 Service de Bactériologie, Groupe Hospitalier Cochin-Saint Vincent de Paul, Assistance Publique Hôpitaux de Paris, Faculté de Médecine René Descartes Université Paris 5, 27 rue du Faubourg Saint Jacques, 75679 Paris Cedex 14, France; 2 Service de Médecine Interne, Groupe Hospitalier Cochin-Saint Vincent de Paul, Assistance Publique Hôpitaux de Paris, Faculté de Médecine René Descartes Université Paris 5, Paris, France

* Corresponding author. Tel: +33-1-58-41-15-60; Fax: +33-1-58-41-15-48; E-mail: claire.poyart@cch.ap-hop-paris.fr

Keywords: P. aeruginosa , ß-lactams , MBLs

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The emergence of acquired metallo-ß-lactamases (MBLs) of the IMP and the VIM types among Gram-negative bacilli is increasing and becoming a life-threatening therapeutic problem. These enzymes are active against most ß-lactams including carbapenems and extended-spectrum cephalosporins except the monobactam aztreonam. Moreover, most of the clinical isolates harbouring such enzymes are also often resistant to other antibiotics such as aminoglycosides and fluoroquinolones. Therefore, antibiotic therapy for treating infections arising . . . [Full Text of this Article]


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