JAC Advance Access originally published online on July 26, 2005
Journal of Antimicrobial Chemotherapy 2005 56(3):598; doi:10.1093/jac/dki265
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© The Author 2005. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oupjournals.org
Correspondence |
Use of Etest MBL strips for the detection of carbapenemases in Acinetobacter baumannii
1 Division of Medical Microbiology, Institute of Infectious Diseases & Molecular Medicine, Medical School, University of Cape Town, Anzio Road, Observatory 7925, Cape Town; 2 National Health Laboratory Service, Groote Schuur Hospital, Cape Town, South Africa
* Corresponding author. Tel: +27-21-4066793; Fax: +27-21-4066796; E-mail: hsegal@curie.uct.ac.za
Keywords: blaOXA-23 , carbapenem resistance , ß-lactamases
| The first 10% of the full text of this article appears below. |
Sir,
In 2002, we saw the emergence of carbapenem resistance in clinical isolates of Acinetobacter baumannii isolated from patients at two local hospitals, Groote Schuur Hospital (GSH) and Tygerberg Hospital (TH), Western Cape, South Africa. The high levels of imipenem (16256 mg/L) and meropenem (>32 mg/L) resistance observed in these A. baumannii isolates suggested the presence of a metallo-ß-lactamase (MBL) or an oxacillinase, since these carbapenemases are considered
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