JAC Advance Access originally published online on March 16, 2005
Journal of Antimicrobial Chemotherapy 2005 55(5):810-811; doi:10.1093/jac/dki080
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© The Author 2005. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oupjournals.org
Correspondence |
Panresistance in VIM-1-producing Klebsiella pneumoniae
1 Laboratory of Bacteriology, Hellenic Pasteur Institute, Vas. Sofias 127, Athens 11521, 2 First Department of Propaedeutic Medicine and 3 Department of Microbiology, Medical School, University of Athens, Athens, Greece
* Corresponding author. Tel: +30-210-6478810; Fax: +30-210-6423498; Email: miriagou@mail.pasteur.gr
Keywords: K. pneumoniae , carbapenems , resistance , metallo-ß-lactamases , VIM-1
| The first 10% of the full text of this article appears below. |
Sir,
The term ‘panresistance’ usually refers to non-fermenting bacilli, such as Pseudomonas and Acinetobacter spp., resistant to all clinically available antimicrobials, except colistin. We report here on four Klebsiella pneumoniae clinical isolates exhibiting this pattern of resistance. The isolates, derived from patients treated in intensive care units in three teaching hospitals in Athens during 2002–2004, were positive for metallo-ß-lactamase (MBL) production. Determination of antibiotic susceptibility by the microdilution method showed high levels of resistance to carboxy- and
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