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JAC Advance Access originally published online on June 23, 2004
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Journal of Antimicrobial Chemotherapy 2004 54(2):570-571; doi:10.1093/jac/dkh344
JAC vol.54 no.2 © The British Society for Antimicrobial Chemotherapy 2004; all rights reserved.

Correspondence

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E. Bertazzoni Minelli1,*, A. Benini1, B. Magnan2 and P. Bartolozzi2

1 Department of Medicine and Public Health, Unit of Pharmacology, Policlinico G. B. Rossi, 37134 Verona; 2 Department of Biomedical and Surgical Sciences, Orthopaedic Clinic, University of Verona, Verona, Italy

Keywords: antibiotic combinations , antibiotic-loaded cement , drug delivery systems , surgical prosthetic infections , topical administration

The first 10% of the full text of this article appears below.

Sir,

We appreciate the comments on our paper by Stallmann et al.1 as they raise a number of important questions relating to the clinical evaluation and the drug release patterns of spacers seen in our study. The primary aim of our study was to evaluate the antibiotic release kinetics for explanted spacers under controlled conditions in vitro. We presented additional data on patient clinical outcome as we felt this provided better information about the overall performance of the spacers. We agree that the . . . [Full Text of this Article]

* Corresponding author. Tel: +39-45-8027603/7611; Fax: +39-45-581111; Email: elisa.bertazzoni@univr.it


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